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anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) Antibodies

NMNAT2 product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Additionally we are shipping NMNAT2 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NMNAT2 23057 Q9BZQ4
Anti-Mouse NMNAT2 NMNAT2 226518 Q8BNJ3
Anti-Rat NMNAT2 NMNAT2 289095 Q0HA29
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Top anti-NMNAT2 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB NMNAT2 monoclonal antibody (M02), clone 4E6. Western Blot analysis of NMNAT2 expression in MCF-7. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB NMNAT2 Antibody (N-term)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the NMNAT2 antibody detected the NMNAT2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged NMNAT2 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Western blot analysis using anti-NMNAT2 (human), mAb (Nady-1)  at 1:2'000 dilution. 1: Human NMNAT2 (His-tagged). 2: Human NMNAT3 (His-tagged). 3: Unrelated (His-tagged) (negative control). 100 μg Log in to see 5 to 8 Days
$299.25
Details
Human Guinea Pig Un-conjugated ELISA, WB Western blot analysis using anti-NMNAT2 (human), pAb  at 1:4'000 dilution. 1: Human NMNAT2 (His-tagged) (50ng). 2: Human mesenchymal stem cell lysate (V1T1) (50μg). 3: Unrelated Protein (His-tagged) (50ng). 100 μg Log in to see 5 to 8 Days
$299.25
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated IF, ELISA Detection limit for recombinant GST tagged NMNAT2 is 3 ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to NMNAT2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

NMNAT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NMNAT2 Antibodies

  1. Human Monoclonal NMNAT2 Primary Antibody for ELISA, WB - ABIN524943 : Yan, Feng, Zheng, Ge, Zhang, Wu, Zhao, Zhai: Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity. in Neurochemistry international 2010 (PubMed)

More Antibodies against NMNAT2 Interaction Partners

Human Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) interaction partners

  1. Knockdown of NMNAT-2 significantly reduces cellular NAD(+) levels and protects cells from p53 (show TP53 Antibodies)-dependent cell death upon DNA damage, suggesting an important functional role of NMNAT-2 in p53 (show TP53 Antibodies)-mediated signaling.

  2. Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is essential for axon growth and survival.

  3. Overexpression of NMNAT2 in colorectal cancer cells renders them sensitive to Tiazofurin antineoplastic action.

  4. affects tau phosphorylation by regulating PP2A (show PPP2R4 Antibodies) activity

  5. Decreased endogenous NMNAT2 function caused by reduced CREB (show CREB1 Antibodies) signaling during pathological insults may be one of underlying mechanisms for neuronal death in tauopathies

  6. that overexpression of Nmnat2 in M-cells significantly delayed axon degeneration in vivo

  7. Nmnat2 is a neuronal protein (show LRCH1 Antibodies) peripherally attached to membranes via palmitoylation and suggest that Nmnat2 is transported to synaptic terminals via an endosomal pathway.

  8. NMNAT1 (show NMNAT1 Antibodies) is a nuclear protein (show RDBP Antibodies), whereas NMNAT2 and -3 are localized to the Golgi complex and the mitochondria

  9. ATP binds before NMN (show NTS Antibodies) with Golgi apparatus NMNAT2. NMNH conversion to NADH by NMNAT1 (show NMNAT1 Antibodies) and NMNAT3 (show NMNAT3 Antibodies) occurs at similar rates, conversion by NMNAT2 is much slower.

Mouse (Murine) Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) interaction partners

  1. Active nerve degeneration requires SARM1 (show SARM1 Antibodies) and MAP kinases, including DLK (show DAPK3 Antibodies), while the NAD+ synthetic enzyme NMNAT2 prevents degeneration.

  2. nicotinamide mononucleotide adenylyltransferase 2-depletion-dependent degeneration of established axons and restricted extension of developing axons are thus both SARM1 (show SARM1 Antibodies) dependent

  3. Data indicate that thioesterases APT1 (show FAS Antibodies)/APT2 (show TAP2 Antibodies) depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) and zDHHC17 (show ZDHHC17 Antibodies) is the strongest candidate palmitoyltransferase for NMNAT2.

  4. Complete loss of Nmnat2 leads to a mature but distended bladder in utero and is not compatible with survival. Moderate loss of Nmnat2 has no effect on bladder development, survival, and has only modest effects on bladder function later in life.

  5. Together, our results establish Nmnat2 localisation and turnover as a valuable target for modulating axon degeneration in vivo.

  6. results suggest an essential role for NMNAT2 during axon growth

  7. Nmnat2 activity supports axon survival through a site of action distinct from Nmnat2 transport vesicles.

  8. Nmnat2 is involved in axon development or survival in a mammal.

  9. Decreased endogenous NMNAT2 function caused by reduced CREB (show CREB1 Antibodies) signaling during pathological insults may be one of underlying mechanisms for neuronal death in tauopathies

  10. Nmnat2 is a neuronal protein (show LRCH1 Antibodies) peripherally attached to membranes via palmitoylation and suggest that Nmnat2 is transported to synaptic terminals via an endosomal pathway.

NMNAT2 Antigen Profile

Protein Summary

This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed\; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NMNAT2

  • nicotinamide nucleotide adenylyltransferase 2 (nmnat2) antibody
  • nicotinamide nucleotide adenylyltransferase 2 (NMNAT2) antibody
  • nicotinamide nucleotide adenylyltransferase 2 (Nmnat2) antibody
  • AI843915 antibody
  • C1orf15 antibody
  • D030041I09Rik antibody
  • NMNAT2 antibody
  • PNAT1 antibody
  • PNAT2 antibody
  • wu:fj59g01 antibody
  • zgc:73048 antibody

Protein level used designations for NMNAT2

NMN adenylyltransferase 2 , naMN adenylyltransferase 1 , nicotinamide mononucleotide adenylyltransferase 2 , nicotinate-nucleotide adenylyltransferase 1 , nicotinamide nucleotide adenylyltransferase 2 , NaMN adenylyltransferase 2 , nicotinate-nucleotide adenylyltransferase 2 , pyridine nucleotide adenylyltransferase 2

GENE ID SPECIES
336257 Danio rerio
610576 Canis lupus familiaris
743583 Pan troglodytes
771393 Gallus gallus
100124800 Xenopus (Silurana) tropicalis
100172391 Pongo abelii
23057 Homo sapiens
226518 Mus musculus
289095 Rattus norvegicus
511042 Bos taurus
Selected quality suppliers for anti-NMNAT2 (NMNAT2) Antibodies
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