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NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Antibodies (308) and NAMPT Proteins (56) and many more products for this protein.
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Human NAMPT ELISA Kit for Competition ELISA - ABIN1979296
Revollo, Grimm, Imai: The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. in The Journal of biological chemistry 2004
Show all 6 references for ABIN1979296
Mouse (Murine) NAMPT ELISA Kit for Sandwich ELISA - ABIN956431
Kanda, Hau, Tada, Tatsuta, Sato, Watanabe: Visfatin enhances CXCL8, CXCL10, and CCL20 production in human keratinocytes. in Endocrinology 2011
Lower apelin (show APLN ELISA Kits) and higher visfatin plasma levels in high normal blood pressure subjects compared to normal or optimal BP individuals could partially explain the higher cardiovascular risk of the high normal BP group.
Studied levels of salivary visfatin, chemerin (show RARRES2 ELISA Kits), and progranulin (show GRN ELISA Kits) and in gingivitis, periodontitis, as well as healthy patients. Salivary progranulin (show GRN ELISA Kits) levels were similar in all groups; chemerin (show RARRES2 ELISA Kits) was detected at higher levels in the periodontitis group compared to the gingivitis and the healthy groups; visfatin levels were higher in patients with gingivitis and periodontitis compared to those of healthy subjects.
Administration of JNK (show MAPK8 ELISA Kits) inhibitor SP600125 or ROS (show ROS1 ELISA Kits) scavenger tocopherol with TMZ and NAMPT inhibitors substantially attenuated the sensitization of NAMPT inhibitor on TMZ antitumor action. Our data indicate a potential value of NAMPT inhibitors in combined use with TMZ for glioblastoma treatment
Increased circulating visfatin are associated with subsequent decline in renal function in nondiabetic hypertensive patients.
High NAMPT expression is associated with neoplasms.
There is an inverse relationship between the visfatin and undercarboxylated osteocalcin (show BGLAP ELISA Kits) in type 2 diabetes patients with diabetic kidney disease.
The results demonstrated that SAA (show SAA1 ELISA Kits) upregulated Visfatin expression in cultured RAW264.7 macrophages and in the primary monocytes.
These findings indicate that genetic variants in PBEF1 gene may modify individual susceptibility to osteoarthritis in the Chinese population.
An increased level of visfatin was a strong risk factor for both early and advanced colorectal cancer in Chinese patients
revealed increased likelihood of metabolic and dyslipidemic manifestations in obese compared to non-obese PCOS patients, while no significant difference was noted in visfatin and resistin (show RETN ELISA Kits) levels among PCOS patients in terms of co-morbid obesity and in comparison to controls
Visfatin upregulated CD36 (show CD36 ELISA Kits) and SRA (show MSR1 ELISA Kits) expression and downregulated ABCA1 (show ABCA1 ELISA Kits) and ABCG1 (show ABCG1 ELISA Kits) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 ELISA Kits)-dependent pathways.
results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (show GRIN2B ELISA Kits)-containing NMDARs
extracellular NAMPT can be actively released by melanoma cells in vitro.
We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (show TLR4 ELISA Kits)).
Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (show PRKAA1 ELISA Kits)-p38 MAPK (show MAPK14 ELISA Kits) pathway.
Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (show SIRT1 ELISA Kits) predisposes the protein to secretion in adipocytes.
Report retinal toxicity of NAMPT inhibitors.
intracellular NAMPT-NAD(+)-SIRT1 (show SIRT1 ELISA Kits) cascade improves post-ischaemic neovascularization
Data suggest that CTRP3 (cartducin) up-regulates expression and secretion of adipokines (adiponectin, leptin, visfatin, and apelin) in adipocytes; these responses to CTRP3 are down-regulated by insulin resistance or inhibition of AMPK signaling.
The Nampt activity of visfatin is involved in chondrocyte and osteoblast activation
In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.
cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.
The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A ELISA Kits) animals.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 ELISA Kits) and PTGS2 (show PTGS2 ELISA Kits), and decreased the expression of SOD2 (show SOD2 ELISA Kits), GPX3 (show GPX3 ELISA Kits), DAB2 (show DAB2 ELISA Kits), and NR3C1 (show NR3C1 ELISA Kits). TNF (show TNF ELISA Kits) and IL6 (show IL6 ELISA Kits) levels were also decreased while those of NAMPT were unaffected.
the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.
These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
pre-B-cell colony enhancing factor 1
, Nicotinamide phosphoribosyltransferase
, nicotinamide phosphoribosyltransferase
, pre-B cell-enhancing factor
, pre-B-cell colony-enhancing factor 1
, pre-B-cell colony-enhancing factor 1 homolog