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NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Kits (112) and NAMPT Proteins (59) and many more products for this protein.
Showing 10 out of 353 products:
Dog (Canine) Polyclonal NAMPT Primary Antibody for ICC, IF - ABIN152026
Ye, Simon, Maloney, Zambelli-Weiner, Gao, Grant, Easley, McVerry, Tuder, Standiford, Brower, Barnes, Garcia: Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. in American journal of respiratory and critical care medicine 2005
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Human Monoclonal NAMPT Primary Antibody for ICC, FACS - ABIN1169028
Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. in FEBS letters 2006
Show all 7 references for 1169028
Human Polyclonal NAMPT Primary Antibody for IP - ABIN250753
Krzysik-Walker, Ocón-Grove, Maddineni, Hendricks, Ramachandran: Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens. in Endocrinology 2008
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Human Polyclonal NAMPT Primary Antibody for IHC (p), WB - ABIN652958
Samal, Sun, Stearns, Xie, Suggs, McNiece: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. in Molecular and cellular biology 1994
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Human Polyclonal NAMPT Primary Antibody for IHC, ELISA - ABIN1169025
Nowell, Richards, Fielding, Ognjanovic, Topley, Williams, Bryant-Greenwood, Jones: Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. in Arthritis and rheumatism 2006
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Human Monoclonal NAMPT Primary Antibody for ELISA, WB - ABIN969344
Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. in European journal of immunology 2003
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Cow (Bovine) Polyclonal NAMPT Primary Antibody for IHC, WB - ABIN2775322
Chen, Chung, Chang, Tsai, Huang, Shin, Lee: Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2006
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Human Monoclonal NAMPT Primary Antibody for EIA, IHC (p) - ABIN336072
Stephens, Vidal-Puig: An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity. in Current opinion in lipidology 2006
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Human Polyclonal NAMPT Primary Antibody for WB - ABIN223662
Gesing, Masternak, Wang, Joseph, Leeuwenburgh, Westbrook, Lewinski, Karbownik-Lewinska, Bartke: Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. in The journals of gerontology. Series A, Biological sciences and medical sciences 2011
It focusing on NAMPT immunometabolic function as a metabokine, NAMPT secretion, NAMPT mechanism of action and possible roles in the cancer micro-environment.
Authors show the gene encoding nicotinic acid phosphoribosyltransferase (show NAPRT1 Antibodies) (NAPRT), a second NAD(+)-producing enzyme, is amplified and overexpressed in a subset of common types of cancer, including ovarian cancer.
This study shows that expression of SDF-1alpha, eNOS (show NOS3 Antibodies) and VEGF (show VEGFA Antibodies) were significantly higher in uterine leiomyoma than myometrium with a different expression pattern according to the size of uterine leiomyoma. However, expressions of visfatin and leptin (show LEP Antibodies) had no significant differences between the two groups.
Results indicate that increased serum visfatin levels are associated with poor prognosis of hepatocellular carcinoma (HCC (show FAM126A Antibodies)), and visfatin may be a potential therapeutic target of HCC (show FAM126A Antibodies).
Nampt expression is a reliable marker of progression in cervical dysplasia and squamous cell carcinoma.
Visfatin increases the nuclear translocation of Akt (show AKT1 Antibodies) and its binding with ABCC1 (show ABCC1 Antibodies). These data showed that visfatin can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (show AKT1 Antibodies)/MRP1 (show MDM4 Antibodies).
Results suggest a mechanism by which tumor cells protect themselves against glucose deprivation-induced oxidative stress by utilizing nicotinamide phosphoribosyltransferase (NAMPT) to maintain NADPH (show NQO1 Antibodies) levels.
The combination of upregulation of the NAD(+) de novo synthesis pathway through QPRT (show QPRT Antibodies) over-expression and NAMPT mutation confers resistance to GMX1778, but the cells are only partially resistant to next-generation NAMPT inhibitors. The resistance mechanisms uncovered herein provide a potential avenue to continue exploration of next generation NAMPT inhibitors to treat neoplasms in the clinic.
this study shows that upstream visfatin SNPs could potentially affect phenotypic outcome in obese children through alteration of circulating visfatin level.
Lack of changes in serum visfatin level despite the changes in visfatin mRNA expression of adipose tissue suggests paracrine effect of visfatin rather than endocrine
role of Nampt in regulating osteoblast differentiation in primary mouse bone marrow-derived mesenchymal stem cells (BM-MSCs); Nampt expression was progressively elevated during BM-MSCs osteogenic differentiation
The results suggest that NCOA6 (show NCOA6 Antibodies) stimulates insulin (show INS Antibodies) secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells.
the protein expression levels of TIMP-2 (show TIMP2 Antibodies) and PBEF in cloned placentae, were examined.
NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 (show SIRT1 Antibodies) AS lncRNA/miR (show MLXIP Antibodies)-22/SIRT1 (show SIRT1 Antibodies) pathway
Visfatin upregulated CD36 (show CD36 Antibodies) and SRA (show MSR1 Antibodies) expression and downregulated ABCA1 (show ABCA1 Antibodies) and ABCG1 (show ABCG1 Antibodies) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Antibodies)-dependent pathways.
results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (show GRIN2B Antibodies)-containing NMDARs
extracellular NAMPT can be actively released by melanoma cells in vitro.
We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)).
Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (show PRKAA1 Antibodies)-p38 MAPK (show MAPK14 Antibodies) pathway.
Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (show SIRT1 Antibodies) predisposes the protein to secretion in adipocytes.
In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.
cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.
The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A Antibodies) animals.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT were unaffected.
the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.
These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
pre-B-cell colony enhancing factor 1
, Nicotinamide phosphoribosyltransferase
, nicotinamide phosphoribosyltransferase
, pre-B cell-enhancing factor
, pre-B-cell colony-enhancing factor 1
, pre-B-cell colony-enhancing factor 1 homolog