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NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Kits (109) and NAMPT Proteins (57) and many more products for this protein.
Showing 10 out of 321 products:
Dog (Canine) Polyclonal NAMPT Primary Antibody for ICC, IF - ABIN152026
Ye, Simon, Maloney, Zambelli-Weiner, Gao, Grant, Easley, McVerry, Tuder, Standiford, Brower, Barnes, Garcia: Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. in American journal of respiratory and critical care medicine 2005
Show all 10 references for ABIN152026
Human Monoclonal NAMPT Primary Antibody for ICC, FACS - ABIN1169028
Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. in FEBS letters 2006
Show all 7 references for ABIN1169028
Human Polyclonal NAMPT Primary Antibody for IP - ABIN250753
Krzysik-Walker, Ocón-Grove, Maddineni, Hendricks, Ramachandran: Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens. in Endocrinology 2008
Show all 3 references for ABIN250753
Human Polyclonal NAMPT Primary Antibody for IHC (p), WB - ABIN652958
Samal, Sun, Stearns, Xie, Suggs, McNiece: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. in Molecular and cellular biology 1994
Show all 3 references for ABIN652958
Human Monoclonal NAMPT Primary Antibody for ELISA, WB - ABIN2869291
Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. in European journal of immunology 2003
Show all 2 references for ABIN2869291
Human Monoclonal NAMPT Primary Antibody for EIA, IHC (p) - ABIN336072
Stephens, Vidal-Puig: An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity. in Current opinion in lipidology 2006
Show all 2 references for ABIN336072
Chicken Polyclonal NAMPT Primary Antibody for WB - ABIN2775321
Chen, Chung, Chang, Tsai, Huang, Shin, Lee: Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2006
Human Polyclonal NAMPT Primary Antibody for WB - ABIN223662
Gesing, Masternak, Wang, Joseph, Leeuwenburgh, Westbrook, Lewinski, Karbownik-Lewinska, Bartke: Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. in The journals of gerontology. Series A, Biological sciences and medical sciences 2011
visfatin can increase the motility of osteosarcoma cells via up regulation of NF-kappaB (show NFKB1 Antibodies)/IL-6 (show IL6 Antibodies) signals
Serum NAMPT is up-regulated and can be considered as a novel surrogate marker of systemic inflammation associated with fat depot, especially visceral, in the elderly population with obesity.
We investigated the association between serum visfatin levels and single nucleotide polymorphisms (SNPs; rs61330082, rs2058539) in the visfatin gene and coronary artery calcification (CAC (show CA2 Antibodies)). The T allele of the rs61330082 SNP in the visfatin gene had a cardioprotective effect on patients with CAC (show CA2 Antibodies); the SNP at rs2058539 was not significantly associated with CAC (show CA2 Antibodies).
Lower level of adiponectin (show ADIPOQ Antibodies) and higher visfatin concentration seem to be related with a less beneficial oxidative stress profile and higher level of lipid peroxidation in neonates exposed and nonexposed in utero to tobacco smoke.
visfatin may represent a model for further study of bone metabolism, and could possibly explain the unknown mechanisms linking bone metabolism and cancer.
Elevated mRNA expression and circulating level of visfatin is associated with the pathogenesis and severity of coronary artery disease.
Data suggest that plasma levels of visfatin are up-regulated in patients with non-small cell lung cancer (NSCLC) as compared to controls; high plasma levels of visfatin correlate with neoplasm stage, lymph node metastasis, and distant metastasis; in vitro, visfatin triggers migration and invasion of NSCLC cells via up-regulation of matrix metalloproteinases 2/9 (MMP2 (show MMP2 Antibodies) and MMP9 (show MMP9 Antibodies)).
Increased serum visfatin, fetuin-A (show AHSG Antibodies), and PTX3 (show PITX3 Antibodies) levels, and the presence of positive correlation between visfatin, fetuin-A (show AHSG Antibodies), and Psoriasis area and severity index, probably reflect the inflammatory state and insulin (show INS Antibodies) resistance seen in psoriasis.
Lower apelin (show APLN Antibodies) and higher visfatin plasma levels in high normal blood pressure subjects compared to normal or optimal BP individuals could partially explain the higher cardiovascular risk of the high normal BP group.
Studied levels of salivary visfatin, chemerin (show RARRES2 Antibodies), and progranulin (show GRN Antibodies) and in gingivitis, periodontitis, as well as healthy patients. Salivary progranulin (show GRN Antibodies) levels were similar in all groups; chemerin (show RARRES2 Antibodies) was detected at higher levels in the periodontitis group compared to the gingivitis and the healthy groups; visfatin levels were higher in patients with gingivitis and periodontitis compared to those of healthy subjects.
Visfatin upregulated CD36 (show CD36 Antibodies) and SRA (show MSR1 Antibodies) expression and downregulated ABCA1 (show ABCA1 Antibodies) and ABCG1 (show ABCG1 Antibodies) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Antibodies)-dependent pathways.
results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (show GRIN2B Antibodies)-containing NMDARs
extracellular NAMPT can be actively released by melanoma cells in vitro.
We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)).
Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (show PRKAA1 Antibodies)-p38 MAPK (show MAPK14 Antibodies) pathway.
Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (show SIRT1 Antibodies) predisposes the protein to secretion in adipocytes.
Report retinal toxicity of NAMPT inhibitors.
intracellular NAMPT-NAD(+)-SIRT1 (show SIRT1 Antibodies) cascade improves post-ischaemic neovascularization
Data suggest that CTRP3 (cartducin) up-regulates expression and secretion of adipokines (adiponectin, leptin, visfatin, and apelin) in adipocytes; these responses to CTRP3 are down-regulated by insulin resistance or inhibition of AMPK signaling.
The Nampt activity of visfatin is involved in chondrocyte and osteoblast activation
In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.
cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.
The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A Antibodies) animals.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT were unaffected.
the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.
These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
pre-B-cell colony enhancing factor 1
, Nicotinamide phosphoribosyltransferase
, nicotinamide phosphoribosyltransferase
, pre-B cell-enhancing factor
, pre-B-cell colony-enhancing factor 1
, pre-B-cell colony-enhancing factor 1 homolog