Nicotinamide phosphoribosyltransferase Proteins (NAMPT)

NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Antibodies (365) and NAMPT Kits (123) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NAMPT 10135 P43490
NAMPT 59027 Q99KQ4
NAMPT 297508 Q80Z29
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Top NAMPT Proteins at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Escherichia coli (E. coli) Human His tag Dimer formation of recombinant Nampt (Visfatin, PBEF) . Purified Nampt (Visfatin, PBEF) was separated by SDS-PAGE and Western blot analysis was performed using rabbit anti-Nampt polyclonal antibody . In the absence of DTT, Nampt (visfatin, PBEF) formed a homodimer, a homomultimer. 50 μg Log in to see 5 to 8 Days
$451.50
Details
Escherichia coli (E. coli) Mouse Un-conjugated 50 μg Log in to see 2 to 3 Days
$345.00
Details
Escherichia coli (E. coli) Mouse His tag   50 μg Log in to see 5 to 8 Days
$451.50
Details
HEK-293 Cells Rat DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
$236.25
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$345.00
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
Escherichia coli (E. coli) Human Un-conjugated   0.025 mg Log in to see 2 to 6 Days
$324.50
Details

NAMPT Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
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Mouse (Murine) , ,
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Rat (Rattus) , ,
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Top referenced NAMPT Proteins

  1. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN1344091 : Yonezawa, Haga, Kobayashi, Takahashi, Obara: Visfatin is present in bovine mammary epithelial cells, lactating mammary gland and milk, and its expression is regulated by cAMP pathway. in FEBS letters 2006 (PubMed)
    Show all 2 Pubmed References

  2. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN413884 : Šenolt, Kuklová, Cerezo, Hulejová, Filková, Bošanská, Pecha, Pavelka, Haluzík, Vencovský: Adipokine profile is modulated in subcutaneous adipose tissue by TNFα inhibitors in patients with rheumatoid arthritis. in Annals of the rheumatic diseases 2011 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN1344090 : Brown, Onyango, Ramanjaneya, Conner, Patel, Dunmore, Randeva: Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells. in Journal of molecular endocrinology 2010 (PubMed)

  4. Rat (Rattus) NAMPT Protein expressed in HEK-293 Cells - ABIN1344283 : Spinnler, Gorski, Stolz, Schuster, Garten, Beck-Sickinger, Engelse, de Koning, Körner, Kiess, Maedler: The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. in PLoS ONE 2013 (PubMed)

  5. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN413887 : Kanda, Hau, Tada, Tatsuta, Sato, Watanabe: Visfatin enhances CXCL8, CXCL10, and CCL20 production in human keratinocytes. in Endocrinology 2011 (PubMed)

More Proteins for Nicotinamide phosphoribosyltransferase (NAMPT) Interaction Partners

Human Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. In summary, NAMPT is produced in human spermatozoa in a maturation-dependent manner.

  2. Non-surgical periodontal treatment resulted in a significant reduction in gingival crevicular fluid and serum visfatin levels. Furthermore, visfatin levels increased with inflammation and decreased following periodontal treatment. Our findings suggest that visfatin is an inflammatory biomarker of periodontal disease

  3. Accordingly, our results demonstrated that NAMPT is a prognostic marker in melanoma, and the identificationofNAMPT-E2F2 (show E2F2 Proteins)-SIRT1 (show SIRT1 Proteins) pathway establishes another link between NAMPT and apoptosis events in melanoma, with therapeutic implications for this deadly cancer.

  4. systemic circulating NAMPT levels were closely associated with NAMPT release from corresponding cultured PBMCs. In conclusion, NAMPT is selectively increased in states of acute but not chronic inflammation in children

  5. It focusing on NAMPT immunometabolic function as a metabokine, NAMPT secretion, NAMPT mechanism of action and possible roles in the cancer micro-environment.

  6. Authors show the gene encoding nicotinic acid phosphoribosyltransferase (show NAPRT1 Proteins) (NAPRT), a second NAD(+)-producing enzyme, is amplified and overexpressed in a subset of common types of cancer, including ovarian cancer.

  7. This study shows that expression of SDF-1alpha, eNOS (show NOS3 Proteins) and VEGF (show VEGFA Proteins) were significantly higher in uterine leiomyoma than myometrium with a different expression pattern according to the size of uterine leiomyoma. However, expressions of visfatin and leptin (show LEP Proteins) had no significant differences between the two groups.

  8. Results indicate that increased serum visfatin levels are associated with poor prognosis of hepatocellular carcinoma (HCC (show FAM126A Proteins)), and visfatin may be a potential therapeutic target of HCC (show FAM126A Proteins).

  9. Nampt expression is a reliable marker of progression in cervical dysplasia and squamous cell carcinoma.

  10. Visfatin increases the nuclear translocation of Akt (show AKT1 Proteins) and its binding with ABCC1 (show ABCC1 Proteins). These data showed that visfatin can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (show AKT1 Proteins)/MRP1 (show MDM4 Proteins).

Mouse (Murine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. NAMPT-mediated NAD(+) biosynthesis in adipocytes regulates adipose tissue function and multi-organ insulin (show INS Proteins) sensitivity in mice.

  2. NAMPT-mediated NAD(+) biosynthesis is essential for vision in mice.

  3. NAMPT is involved in key basic cellular functions.

  4. role of Nampt in regulating osteoblast differentiation in primary mouse bone marrow-derived mesenchymal stem cells (BM-MSCs); Nampt expression was progressively elevated during BM-MSCs osteogenic differentiation

  5. The results suggest that NCOA6 (show NCOA6 Proteins) stimulates insulin (show INS Proteins) secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells.

  6. the protein expression levels of TIMP-2 (show TIMP2 Proteins) and PBEF in cloned placentae, were examined.

  7. NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 (show SIRT1 Proteins) AS lncRNA/miR (show MLXIP Proteins)-22/SIRT1 (show SIRT1 Proteins) pathway

  8. Visfatin upregulated CD36 (show CD36 Proteins) and SRA (show MSR1 Proteins) expression and downregulated ABCA1 (show ABCA1 Proteins) and ABCG1 (show ABCG1 Proteins) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Proteins)-dependent pathways.

  9. results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (show GRIN2B Proteins)-containing NMDARs

  10. extracellular NAMPT can be actively released by melanoma cells in vitro.

Pig (Porcine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.

  2. cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.

  3. The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A Proteins) animals.

Cow (Bovine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Proteins) and PTGS2 (show PTGS2 Proteins), and decreased the expression of SOD2 (show SOD2 Proteins), GPX3 (show GPX3 Proteins), DAB2 (show DAB2 Proteins), and NR3C1 (show NR3C1 Proteins). TNF (show TNF Proteins) and IL6 (show IL6 Proteins) levels were also decreased while those of NAMPT were unaffected.

  2. the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.

  3. These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.

NAMPT Protein Profile

Protein Summary

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

Gene names and symbols associated with NAMPT

  • nicotinamide phosphoribosyltransferase (NAMPT)
  • nicotinamide phosphoribosyltransferase (Nampt)
  • nicotinamide phosphoribosyltransferase (nampt)
  • Nicotinamide phosphoribosyltransferase (Smon_0680)
  • Nicotinamide phosphoribosyltransferase (Mrub_2845)
  • nicotinamide phosphoribosyltransferase (Cseg_3704)
  • Nicotinamide phosphoribosyltransferase (BC1002_3997)
  • nicotinamide phosphoribosyltransferase (Ftrac_2686)
  • nicotinamide phosphoribosyltransferase (Varpa_5681)
  • nicotinamide phosphoribosyltransferase (Celal_3900)
  • Nicotinamide phosphoribosyltransferase (Deima_0880)
  • Nicotinamide phosphoribosyltransferase (BC1001_3724)
  • Nicotinamide phosphoribosyltransferase (Celly_1696)
  • Nicotinamide phosphoribosyltransferase (Clole_1542)
  • nicotinamide phosphoribosyltransferase (Tsp_05934)
  • nicotinamide phosphoribosyltransferase S homeolog (nampt.S)
  • 1110035O14Rik protein
  • AI314458 protein
  • AI480535 protein
  • NAmPRTase protein
  • pbef protein
  • pbef1 protein
  • VF protein
  • visfatin protein

Protein level used designations for NAMPT

NAmPRTase , pre-B cell-enhancing factor , pre-B-cell colony enhancing factor 1 , pre-B-cell colony-enhancing factor 1 , pre-B-cell colony-enhancing factor 1 homolog , visfatin , PBEF , Nicotinamide phosphoribosyltransferase , nicotinamide phosphoribosyltransferase , pre-B-cell colony-enhancing factor-like protein

GENE ID SPECIES
10135 Homo sapiens
59027 Mus musculus
417707 Gallus gallus
100223583 Taeniopygia guttata
595123 Sus scrofa
463648 Pan troglodytes
520472 Bos taurus
297508 Rattus norvegicus
496856 Xenopus (Silurana) tropicalis
8600403 Streptobacillus moniliformis DSM 12112
8880961 Meiothermus ruber DSM 1279
9105230 Caulobacter segnis ATCC 21756
9113310 Burkholderia sp. CCGE1002
10012838 Marivirga tractuosa DSM 4126
10132554 Variovorax paradoxus EPS
10146329 Cellulophaga algicola DSM 14237
10150218 Deinococcus maricopensis DSM 21211
10225315 Burkholderia sp. CCGE1001
10263712 Cellulophaga lytica DSM 7489
10331257 Clostridium lentocellum DSM 5427
10911088 Trichinella spiralis
398502 Xenopus laevis
100059684 Equus caballus
100856598 Canis lupus familiaris
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