Nicotinamide phosphoribosyltransferase Proteins (NAMPT)

NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Antibodies (353) and NAMPT Kits (112) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NAMPT 10135 P43490
NAMPT 59027 Q99KQ4
NAMPT 297508 Q80Z29
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Top NAMPT Proteins at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag Dimer formation of recombinant Nampt (Visfatin, PBEF) . Purified Nampt (Visfatin, PBEF) was separated by SDS-PAGE and Western blot analysis was performed using rabbit anti-Nampt polyclonal antibody . In the absence of DTT, Nampt (visfatin, PBEF) formed a homodimer, a homomultimer. 50 μg Log in to see 5 to 8 Days
$451.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 50 μg Log in to see 2 to 3 Days
$345.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag   50 μg Log in to see 5 to 8 Days
$451.50
Details
HOST_HEK-293 Cells Rat DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
$236.25
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$345.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 10 to 12 Days
$86.96
Details

NAMPT Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) , ,
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Rat (Rattus) , ,
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Top referenced NAMPT Proteins

  1. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN2667609 : Sommer, Garten, Petzold, Beck-Sickinger, Blüher, Stumvoll, Fasshauer: Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. in Clinical science (London, England : 1979) 2008 (PubMed)
    Show all 4 references for 2667609

  2. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN667699 : Hug, Lodish: Medicine. Visfatin: a new adipokine. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 2 references for 667699

  3. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN413884 : Šenolt, Kuklová, Cerezo, Hulejová, Filková, Bošanská, Pecha, Pavelka, Haluzík, Vencovský: Adipokine profile is modulated in subcutaneous adipose tissue by TNFα inhibitors in patients with rheumatoid arthritis. in Annals of the rheumatic diseases 2011 (PubMed)
    Show all 2 references for 413884

  4. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN1344091 : Yonezawa, Haga, Kobayashi, Takahashi, Obara: Visfatin is present in bovine mammary epithelial cells, lactating mammary gland and milk, and its expression is regulated by cAMP pathway. in FEBS letters 2006 (PubMed)
    Show all 2 references for 1344091

  5. Human NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN666706 : Stephens, Vidal-Puig: An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity. in Current opinion in lipidology 2006 (PubMed)

  6. Rat (Rattus) NAMPT Protein expressed in HEK-293 Cells - ABIN1344283 : Spinnler, Gorski, Stolz, Schuster, Garten, Beck-Sickinger, Engelse, de Koning, Körner, Kiess, Maedler: The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. in PLoS ONE 2013 (PubMed)

  7. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN413887 : Kanda, Hau, Tada, Tatsuta, Sato, Watanabe: Visfatin enhances CXCL8, CXCL10, and CCL20 production in human keratinocytes. in Endocrinology 2011 (PubMed)

  8. Mouse (Murine) NAMPT Protein expressed in Escherichia coli (E. coli) - ABIN1344090 : Brown, Onyango, Ramanjaneya, Conner, Patel, Dunmore, Randeva: Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells. in Journal of molecular endocrinology 2010 (PubMed)

More Proteins for Nicotinamide phosphoribosyltransferase (NAMPT) Interaction Partners

Human Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. Authors show the gene encoding nicotinic acid phosphoribosyltransferase (show NAPRT1 Proteins) (NAPRT), a second NAD(+)-producing enzyme, is amplified and overexpressed in a subset of common types of cancer, including ovarian cancer.

  2. This study shows that expression of SDF-1alpha, eNOS (show NOS3 Proteins) and VEGF (show VEGFA Proteins) were significantly higher in uterine leiomyoma than myometrium with a different expression pattern according to the size of uterine leiomyoma. However, expressions of visfatin and leptin (show LEP Proteins) had no significant differences between the two groups.

  3. Results indicate that increased serum visfatin levels are associated with poor prognosis of hepatocellular carcinoma (HCC (show FAM126A Proteins)), and visfatin may be a potential therapeutic target of HCC (show FAM126A Proteins).

  4. Nampt expression is a reliable marker of progression in cervical dysplasia and squamous cell carcinoma.

  5. Visfatin increases the nuclear translocation of Akt (show AKT1 Proteins) and its binding with ABCC1 (show ABCC1 Proteins). These data showed that visfatin can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (show AKT1 Proteins)/MRP1 (show MDM4 Proteins).

  6. Results suggest a mechanism by which tumor cells protect themselves against glucose deprivation-induced oxidative stress by utilizing nicotinamide phosphoribosyltransferase (NAMPT) to maintain NADPH (show NQO1 Proteins) levels.

  7. The combination of upregulation of the NAD(+) de novo synthesis pathway through QPRT (show QPRT Proteins) over-expression and NAMPT mutation confers resistance to GMX1778, but the cells are only partially resistant to next-generation NAMPT inhibitors. The resistance mechanisms uncovered herein provide a potential avenue to continue exploration of next generation NAMPT inhibitors to treat neoplasms in the clinic.

  8. this study shows that upstream visfatin SNPs could potentially affect phenotypic outcome in obese children through alteration of circulating visfatin level.

  9. Lack of changes in serum visfatin level despite the changes in visfatin mRNA expression of adipose tissue suggests paracrine effect of visfatin rather than endocrine

  10. Ascending aorta from aortic aneurysm patient,s revealed an inverse relationship between smooth muscle cell NAMPT content and aortic diameter.

Mouse (Murine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. role of Nampt in regulating osteoblast differentiation in primary mouse bone marrow-derived mesenchymal stem cells (BM-MSCs); Nampt expression was progressively elevated during BM-MSCs osteogenic differentiation

  2. The results suggest that NCOA6 (show NCOA6 Proteins) stimulates insulin (show INS Proteins) secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells.

  3. the protein expression levels of TIMP-2 (show TIMP2 Proteins) and PBEF in cloned placentae, were examined.

  4. NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 (show SIRT1 Proteins) AS lncRNA/miR (show MLXIP Proteins)-22/SIRT1 (show SIRT1 Proteins) pathway

  5. Visfatin upregulated CD36 (show CD36 Proteins) and SRA (show MSR1 Proteins) expression and downregulated ABCA1 (show ABCA1 Proteins) and ABCG1 (show ABCG1 Proteins) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Proteins)-dependent pathways.

  6. results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (show GRIN2B Proteins)-containing NMDARs

  7. extracellular NAMPT can be actively released by melanoma cells in vitro.

  8. We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (show TLR4 Proteins)).

  9. Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (show PRKAA1 Proteins)-p38 MAPK (show MAPK14 Proteins) pathway.

  10. Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (show SIRT1 Proteins) predisposes the protein to secretion in adipocytes.

Pig (Porcine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.

  2. cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.

  3. The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A Proteins) animals.

Cow (Bovine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Proteins) and PTGS2 (show PTGS2 Proteins), and decreased the expression of SOD2 (show SOD2 Proteins), GPX3 (show GPX3 Proteins), DAB2 (show DAB2 Proteins), and NR3C1 (show NR3C1 Proteins). TNF (show TNF Proteins) and IL6 (show IL6 Proteins) levels were also decreased while those of NAMPT were unaffected.

  2. the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.

  3. These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.

NAMPT Protein Profile

Protein Summary

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

Gene names and symbols associated with NAMPT

  • nicotinamide phosphoribosyltransferase (NAMPT)
  • nicotinamide phosphoribosyltransferase (nampt)
  • Nicotinamide phosphoribosyltransferase (Smon_0680)
  • Nicotinamide phosphoribosyltransferase (Mrub_2845)
  • nicotinamide phosphoribosyltransferase (Cseg_3704)
  • Nicotinamide phosphoribosyltransferase (BC1002_3997)
  • nicotinamide phosphoribosyltransferase (Ftrac_2686)
  • nicotinamide phosphoribosyltransferase (Varpa_5681)
  • nicotinamide phosphoribosyltransferase (Celal_3900)
  • Nicotinamide phosphoribosyltransferase (Deima_0880)
  • Nicotinamide phosphoribosyltransferase (BC1001_3724)
  • Nicotinamide phosphoribosyltransferase (Celly_1696)
  • Nicotinamide phosphoribosyltransferase (Clole_1542)
  • Nicotinamide phosphoribosyltransferase (Psed_2146)
  • Nicotinamide phosphoribosyltransferase (Psed_2158)
  • nicotinamide phosphoribosyltransferase (Tsp_05934)
  • nicotinamide phosphoribosyltransferase (Nampt)
  • 1110035O14Rik protein
  • AI314458 protein
  • AI480535 protein
  • NAmPRTase protein
  • Pbef protein
  • Pbef1 protein
  • VF protein
  • visfatin protein

Protein level used designations for NAMPT

pre-B-cell colony enhancing factor 1 , visfatin , Nicotinamide phosphoribosyltransferase , nicotinamide phosphoribosyltransferase , NAmPRTase , pre-B cell-enhancing factor , pre-B-cell colony-enhancing factor 1 , pre-B-cell colony-enhancing factor 1 homolog , PBEF

GENE ID SPECIES
463648 Pan troglodytes
100223583 Taeniopygia guttata
496856 Xenopus (Silurana) tropicalis
8600403 Streptobacillus moniliformis DSM 12112
8880961 Meiothermus ruber DSM 1279
9105230 Caulobacter segnis ATCC 21756
9113310 Burkholderia sp. CCGE1002
10012838 Marivirga tractuosa DSM 4126
10132554 Variovorax paradoxus EPS
10146329 Cellulophaga algicola DSM 14237
10150218 Deinococcus maricopensis DSM 21211
10225315 Burkholderia sp. CCGE1001
10263712 Cellulophaga lytica DSM 7489
10331257 Clostridium lentocellum DSM 5427
10363982 Pseudonocardia dioxanivorans CB1190
10363994 Pseudonocardia dioxanivorans CB1190
10911088 Trichinella spiralis
10135 Homo sapiens
59027 Mus musculus
398502 Xenopus laevis
417707 Gallus gallus
483267 Canis lupus familiaris
595123 Sus scrofa
297508 Rattus norvegicus
520472 Bos taurus
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