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The mouse ortholog of NRK encodes a protein kinase required for JNK activation. Additionally we are shipping Nik Related Kinase Antibodies (6) and Nik Related Kinase Kits (2) and many more products for this protein.
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The results suggest that Nrk suppresses the excessive proliferation of mammary epithelial cells during pregnancy, and the impairment of this regulatory system leads to frequent occurrence of breast tumor in Nrk mutant mice.
regulates trophoblast proliferation and placental development by modulating AKT (show AKT1 Proteins) phosphorylation
Nrk, an X-linked protein kinase (show CDK7 Proteins) in the germinal center kinase (show MAP4K2 Proteins) family, is required for placental development and fetoplacental induction of labor.
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.
nik-related protein kinase
, Nik related kinase
, nik-related protein kinase-like
, NIK-like embryo-specific kinase
, nck-interacting kinase-like embryo specific kinase