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Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. Additionally we are shipping NOSTRIN Kits (10) and NOSTRIN Proteins (9) and many more products for this protein.
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NOSTRIN expression is an important factor for the integrity of the glomerular filtration barrier. Disease-related alteration of NOSTRIN expression may affect the vascular endothelium and contribute to the development of podocyte disease and proteinuria.
NOSTRIN is crucial for the localization and function of the muscarinic M3 receptor at the plasma membrane in the aorta.
mouse NOSTRIN acts as a transcriptional repressor by binding to the cis (show CISH Antibodies)-element through its bZIP motif.
NOSTRIN participates in FGF signal transduction and vascular development.
Results reveal an elegant mechanism of eNOS (show NOS3 Antibodies) regulation by PECAM-1 (show PECAM1 Antibodies) through signal transducers and activators of transcription 3-mediated transcriptional control of NOSTRIN.
shares 82% identity with human NOSTRIN; functions in a different fashion from NOSTRIN and its function may be concerted with that of disabled 2(disabled 2 interacting protein 2)
This study showed that overexpression of NOSTRIN had a significant effect on eNOS (show NOS3 Antibodies) activity in HUVECs and resulted in significant cellular damage.
The expression of NOSTRIN is decreased, while the activity of eNOS and the level of NO2-/NO3- increased in the testis tissue of azoospermia patients.
NOSTRIN expression was increased in umbilical vessel of women with pre-eclampsia.
NOSTRIN modulates nitric oxide release and subcellular distribution of endothelial nitric oxide synthase (show NOS3 Antibodies).
NOSTRIN may facilitate endocytosis of endothelial nitric oxide synthase (show NOS3 Antibodies) by coordinating the function of dynamin (show DNM1 Antibodies) and the actin nucleation promoting factor N-WASP (show WASL Antibodies).
A ternary complex between NOSTRIN, caveolin-1 (show CAV1 Antibodies), and eNOS (show NOS3 Antibodies) mediates translocation of eNOS (show NOS3 Antibodies), with important implications for the activity and availability of eNOS (show NOS3 Antibodies) in the cell.
results suggest that nuclear NOSTRINbeta may negatively regulate transcription of the NOSTRIN gene
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS\; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
nitric oxide synthase trafficker
, nitric oxide synthase trafficking
, Dab2-interacting protein 2
, disabled homolog 2-interacting protein 2
, eNOS trafficking inducer
, eNOS-trafficking inducer
, probable ortholog of human nitric oxide synthase trafficker (NOSTRIN)
, BM247 homolog
, ENOS traffic inducer
, endothelial nitric oxide synthase traffic inducer
, nitric oxide synthase traffic inducer
, ortholog of mouse disabled 2 interacting proein 2