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Has a omega-amidase activity. Additionally we are shipping NIT2 Proteins (16) and many more products for this protein.
Showing 10 out of 33 products:
Chicken Polyclonal NIT2 Primary Antibody for WB - ABIN2782571
Lin, Chung, Chen, Chien: Growth inhibitory effect of the human NIT2 gene and its allelic imbalance in cancers. in The FEBS journal 2007
Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 (show CASP3 Antibodies) and PARP (show COL11A2 Antibodies) pathways
Human NIT1/2 (show NIT1 Antibodies) are not involved in the metabolism of vildagliptin.
The activity and substrate specificity of human Nit2 was determined with alpha-ketoglutaramate and succinamate as substrates.
Genotype analysis in 4 types of tumor tissue showed allelic imbalance surrounding NIT2 locus; results show that NIT2 plays an important role in cell growth inhibition & links to malignancies, suggesting Nit2 may be a potential tumor suppressor candidate
Data conclude that mammalian nitrilase 2 is omega-amidase (show GATA1 Antibodies).
Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively (By similarity).
Nit protein 2
, Nitrilase homolog 2-A
, nitrilase homolog 2
, omega-amidase NIT2-A
, nitrilase family, member 2
, omega-amidase NIT2
, Nitrilase homolog 2