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Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) ELISA Kits

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Additionally we are shipping NPRL2 Antibodies (79) and NPRL2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NPRL2 NPRL2 56032 Q9WUE4
Anti-Human NPRL2 NPRL2 10641 Q8WTW4
Anti-Rat NPRL2 NPRL2 363138  
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More ELISA Kits for NPRL2 Interaction Partners

Human Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) interaction partners

  1. NPRL2 mutations are significant cause of focal epilepsy.

  2. NPRL2 acts as a functional tumor suppressor in colorectal cancer cell lines.

  3. NPRL2 enhances sensitivity to oxaliplatin in colon cancer cells.

  4. Decreased expression of NPRL2 is associated with renal cancer.

  5. NPRL2 mRNA blood levels could be a potentially useful marker for the detection of early stage adenomas and colorectal cancers.

  6. Results provide a set of genetic and biologic proofs that TUSC4 functions as a bona fide tumor suppressor by regulating the protein stability and function of BRCA1 in breast cancer.

  7. NPRL2 expression is negatively related with the survival of osteosarcoma patients, indicating its value as a prognosis factor of osteosarcoma.

  8. Lower NPRL2 expression was observed significantly more frequently in poorly differentiated tumor samples than in highly or moderately differentiated colon tumors.

  9. tumor suppressor genes RBSP3/CTDSPL (show CTDSPL ELISA Kits), NPRL2/G21 and RASSF1A (show RASSF1 ELISA Kits) are downregulated in primary non-small cell lung cancer

  10. Data indicate that Npr2, a homolog of human NPRL2, is a phosphorylation-dependent target of the SCF(Grr1) E3 ubiquitin ligase that plays a role in cell growth on some nitrogen sources.

NPRL2 Antigen Profile

Antigen Summary

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.

Gene names and symbols associated with NPRL2

  • nitrogen permease regulator-like 2 (Nprl2) antibody
  • nitrogen permease regulator-like 2 (nprl2) antibody
  • nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) antibody
  • nitrogen permease regulator-like 2 (S. cerevisiae) (Nprl2) antibody
  • nitrogen permease regulator-like 2 (S. cerevisiae) (nprl2) antibody
  • 2810446G01Rik antibody
  • G21 antibody
  • im:6900399 antibody
  • NPR2 antibody
  • npr2l antibody
  • TUSC4 antibody
  • zgc:153630 antibody

Protein level used designations for NPRL2

NPR2-like protein , gene 21 protein , nitrogen permase homolog , nitrogen permease regulator 2-like protein , tumor suppressor candidate 4 , 2810446G01Rik , G21 protein , homologous to yeast nitrogen permease (candidate tumor suppressor)

GENE ID SPECIES
56032 Mus musculus
379794 Xenopus laevis
10641 Homo sapiens
476614 Canis lupus familiaris
508487 Bos taurus
363138 Rattus norvegicus
559391 Danio rerio
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