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NmrA-Like Family Domain Containing 1 Proteins (NMRAL1)

Redox sensor protein. Additionally we are shipping NMRAL1 Antibodies (13) and NMRAL1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NMRAL1 57407 Q9HBL8
NMRAL1 67824 Q8K2T1
NMRAL1 287063  
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Top NMRAL1 Proteins at

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

NMRAL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

Top referenced NMRAL1 Proteins

  1. Human NMRAL1 Protein expressed in Escherichia coli (E. coli) - ABIN1098305 : Gan, Li, Hu, Lian, Zheng: HSCARG inhibits activation of NF-kappaB by interacting with IkappaB kinase-beta. in Journal of cell science 2009 (PubMed)
    Show all 2 references for ABIN1098305

More Proteins for NmrA-Like Family Domain Containing 1 (NMRAL1) Interaction Partners

Human NmrA-Like Family Domain Containing 1 (NMRAL1) interaction partners

  1. After viral infection, HSCARG interacted with tumor necrosis receptor-associated factor 3 (TRAF3 (show TRAF3 Proteins)) and inhibited its ubiquitination by promoting the recruitment of OTUB1 (show OTUB1 Proteins) to TRAF3 (show TRAF3 Proteins).

  2. Data indicate that HSCARG and USP7 (show USP7 Proteins) function in concert in inhibiting polyubiquination of NEMO (show IKBKG Proteins), thus inhibiting NF-kappaB (show NFKB1 Proteins) activity.

  3. HSCARG is involved in DNA damage response through affecting the level of H2A ubiquitination and localization of RAP80 (show UIMC1 Proteins) at lesion points.

  4. HSCARG regulated reactive-oxygen-species homeostasis through inhibition of NADPH oxidase activity via regulation of the expression of p47phox.

  5. CRM1 dependent nucleocytoplasmic translocation of HSCARG plays an important role in fine-tuning NF-kappaB (show NFKB1 Proteins) signaling

  6. HSCARG is involved in the NF-kappaB (show NFKB1 Proteins) signaling pathway, and negatively regulates NF-kappaB (show NFKB1 Proteins) activation.

  7. expression, crystallization and preliminary X-ray crystallographic studies of HSCARG at a resolution of 2.4 A; crystals belong to F23 (show CISH Proteins) space group, with unit cell parameters a=b=c=223.30A, alpha=beta=gamma=90 degrees

  8. One of the functions regulated by HSCARG may be argininosuccinate synthetase that is involved in NO synthesis

  9. HSCARG regulation of argininosuccinate synthetase activity is crucial for maintaining the intracellular balance between redox state and nitric oxide levels

  10. In response to the changes in the NADPH (show NQO1 Proteins)/NADP(+) ratio within cells, HSCARG, as a redox sensor, associates and dissociates with NADPH (show NQO1 Proteins) to form a new dynamic equilibrium.

NMRAL1 Protein Profile

Protein Summary

Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer (By similarity).

Gene names and symbols associated with NMRAL1

  • NmrA-like family domain containing 1 (NMRAL1)
  • NmrA-like family domain containing 1 (Nmral1)
  • 1110025F24Rik protein
  • AI256624 protein
  • HSCARG protein
  • RGD1311451 protein
  • SDR48A1 protein

Protein level used designations for NMRAL1

nmrA-like family domain-containing protein 1 , short chain dehydrogenase/reductase family 48A, member 1

416672 Gallus gallus
57407 Homo sapiens
490026 Canis lupus familiaris
534628 Bos taurus
67824 Mus musculus
287063 Rattus norvegicus
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