You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) Antibodies

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Additionally we are shipping NSMCE2 Proteins (8) and NSMCE2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NSMCE2 111648  
NSMCE2 286053 Q96MF7
NSMCE2 299957 Q4V8A0
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-NSMCE2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MMS21 in 293 cell lysate with MMS21 antibody at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NSMCE2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of NSMCE2 expression in transfected 293T cell line by NSMCE2 MaxPab polyclonal antibody.Lane 1: C8orf36 transfected lysate(27.17 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to NSMCE2 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC207639 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-NSMCE2 antibody (ABIN2453380), and then analyzed by flow cytometry. Anti-NSMCE2 mouse monoclonal antibody (ABIN2453380) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NSMCE2 (RC207639). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated WB NSMCE2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of MMS21 in 293 cell lysate with MMS21 antibody at (A) 0.5 and (B) 1 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 11 to 16 Days
$509.14
Details

NSMCE2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , , ,
,
,
, , , , , , , , , , , , , , , , ,
Rat (Rattus)


Top referenced anti-NSMCE2 Antibodies

  1. Human Polyclonal NSMCE2 Primary Antibody for EIA, WB - ABIN783606 : Behlke-Steinert, Touat-Todeschini, Skoufias, Margolis: SMC5 and MMS21 are required for chromosome cohesion and mitotic progression. in Cell cycle (Georgetown, Tex.) 2009 (PubMed)
    Show all 3 references for ABIN783606

  2. Human Polyclonal NSMCE2 Primary Antibody for IF, WB - ABIN531598 : Chung, Leonhardt, Rippe: De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation. in Journal of cell science 2011 (PubMed)
    Show all 2 references for ABIN531598

More Antibodies against NSMCE2 Interaction Partners

Mouse (Murine) Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) interaction partners

  1. SUMO- and BLM-independent activities of NSMCE2 limit recombination and facilitate chromosome segregation.

Human Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) interaction partners

  1. our study identified novel PVT1-NSMCE2 and CCDC26-NSMCE2 fusion genes that may play functional roles in leukemia.

  2. support a role for NSMCE2 in recovery from DNA damage and raise the possibility that loss of its function produces dwarfism through reduced tolerance of replicative stress

  3. show that the Smc5 (show SMC5 Antibodies)/6 subunit Mms21 sumoylates multiple lysines of the cohesin subunit Scc1 (show PTPRJ Antibodies)

  4. Studies indicate that Nse1 (show FAM84A Antibodies) may function as a ubiquitin ligase, and is targeted to chromatin through its interaction with the Smc5 (show SMC5 Antibodies)/6 complex.

  5. the human SMC5 (show SMC5 Antibodies)/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair in human cells

  6. MMS21 dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression and that this function appears to be independent of SMC6 (show SMC6 Antibodies).

NSMCE2 Antigen Profile

Protein Summary

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).

Gene names and symbols associated with NSMCE2

  • E3 SUMO-protein ligase NSE2 (nsmce2) antibody
  • minisatellites detected by probe MMS21 (Ms21) antibody
  • non-SMC element 2 homolog (MMS21, S. cerevisiae) (Nsmce2) antibody
  • non-SMC element 2, MMS21 homolog (S. cerevisiae) (NSMCE2) antibody
  • non-SMC element 2, MMS21 homolog (S. cerevisiae) (Nsmce2) antibody
  • 1110014D18Rik antibody
  • AI661537 antibody
  • C8orf36 antibody
  • MMS21 antibody
  • NSE2 antibody
  • RGD1305156 antibody
  • ZMIZ7 antibody

Protein level used designations for NSMCE2

MMS21 homolog , non-SMC element 2 homolog , non-structural maintenance of chromosomes element 2 homolog , E3 SUMO-protein ligase NSE2 , hMMS21 , methyl methanesulfonate sensitivity gene 21 , zinc finger, MIZ-type containing 7 , non-SMC element 2 homolog (MMS21, S. cerevisiae)

GENE ID SPECIES
379272 Xenopus laevis
111648 Mus musculus
68501 Mus musculus
286053 Homo sapiens
519974 Bos taurus
299957 Rattus norvegicus
Selected quality suppliers for anti-NSMCE2 (NSMCE2) Antibodies
Did you look for something else?