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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) ELISA Kits

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Additionally we are shipping NSMCE2 Antibodies (42) and NSMCE2 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NSMCE2 NSMCE2 111648  
NSMCE2 286053 Q96MF7
Anti-Rat NSMCE2 NSMCE2 299957 Q4V8A0
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Top NSMCE2 ELISA Kits at antibodies-online.com

Showing 1 out of 1 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 7 pg/ml 28-1800 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

Top referenced NSMCE2 ELISA Kits

  1. Human NSMCE2 ELISA Kit for Sandwich ELISA - ABIN819150 : Yusof, Mehde, Mehdi, Raus, Ghazali, Rahman: Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals. in Biomedical and environmental sciences : BES 2015 (PubMed)

More ELISA Kits for NSMCE2 Interaction Partners

Mouse (Murine) Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) interaction partners

  1. SUMO- and BLM-independent activities of NSMCE2 limit recombination and facilitate chromosome segregation.

Human Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) interaction partners

  1. our study identified novel PVT1-NSMCE2 and CCDC26-NSMCE2 fusion genes that may play functional roles in leukemia.

  2. support a role for NSMCE2 in recovery from DNA damage and raise the possibility that loss of its function produces dwarfism through reduced tolerance of replicative stress

  3. show that the Smc5 (show SMC5 ELISA Kits)/6 subunit Mms21 sumoylates multiple lysines of the cohesin subunit Scc1 (show PTPRJ ELISA Kits)

  4. Studies indicate that Nse1 (show FAM84A ELISA Kits) may function as a ubiquitin ligase, and is targeted to chromatin through its interaction with the Smc5 (show SMC5 ELISA Kits)/6 complex.

  5. the human SMC5 (show SMC5 ELISA Kits)/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair in human cells

  6. MMS21 dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression and that this function appears to be independent of SMC6.

NSMCE2 Antigen Profile

Antigen Summary

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).

Gene names and symbols associated with NSMCE2

  • E3 SUMO-protein ligase NSE2 (nsmce2) antibody
  • minisatellites detected by probe MMS21 (Ms21) antibody
  • non-SMC element 2 homolog (MMS21, S. cerevisiae) (Nsmce2) antibody
  • non-SMC element 2, MMS21 homolog (S. cerevisiae) (NSMCE2) antibody
  • non-SMC element 2, MMS21 homolog (S. cerevisiae) (Nsmce2) antibody
  • 1110014D18Rik antibody
  • AI661537 antibody
  • C8orf36 antibody
  • MMS21 antibody
  • NSE2 antibody
  • RGD1305156 antibody
  • ZMIZ7 antibody

Protein level used designations for NSMCE2

MMS21 homolog , non-SMC element 2 homolog , non-structural maintenance of chromosomes element 2 homolog , E3 SUMO-protein ligase NSE2 , hMMS21 , methyl methanesulfonate sensitivity gene 21 , zinc finger, MIZ-type containing 7 , non-SMC element 2 homolog (MMS21, S. cerevisiae)

GENE ID SPECIES
379272 Xenopus laevis
111648 Mus musculus
68501 Mus musculus
286053 Homo sapiens
519974 Bos taurus
299957 Rattus norvegicus
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