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Expression of interleukin-3 (IL3\; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Additionally we are shipping NFIL3 Kits (21) and NFIL3 Proteins (5) and many more products for this protein.
Showing 10 out of 92 products:
Human Polyclonal NFIL3 Primary Antibody for EIA, WB - ABIN953692
Lavebratt, Sjöholm, Partonen, Schalling, Forsell: PER2 variantion is associated with depression vulnerability. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010
Show all 2 references for ABIN953692
Chicken Polyclonal NFIL3 Primary Antibody for WB - ABIN2777219
Priceman, Kirzner, Nary, Morris, Shankar, Sakamoto, Medh: Calcium-dependent upregulation of E4BP4 expression correlates with glucocorticoid-evoked apoptosis of human leukemic CEM cells. in Biochemical and biophysical research communications 2006
Human Polyclonal NFIL3 Primary Antibody for ELISA, WB - ABIN1533931
Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: DNA sequence and analysis of human chromosome 9. ... in Nature 2004
Human Polyclonal NFIL3 Primary Antibody for ELISA, WB - ABIN184644
Zhang, Zhang, Kornuc, Kwan, Frank, Nimer: Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter. in Molecular and cellular biology 1995
Cow (Bovine) Polyclonal NFIL3 Primary Antibody for WB - ABIN2780681
Ozkurt, Tetradis: Parathyroid hormone-induced E4BP4/NFIL3 down-regulates transcription in osteoblasts. in The Journal of biological chemistry 2003
glucocorticoid-mediated transactivating pathway may support eosinophil viability in IL-5 (show IL5 Antibodies)-stimulated cells through synergistic upregulation of NFIL3
E4BP4 and BIM (show BCL2L11 Antibodies) regulation correlated with that of RCAN1 (show RCAN1 Antibodies)-1. A putative GRE and four EBPREs were identified within 1500bp upstream from the transcription start site of RCAN1 (show RCAN1 Antibodies)-1
Results conclude that the transcriptional repressor E4BP4 plays a role in repressing epigenetically regulated SOSTDC1 (show SOSTDC1 Antibodies) expression in breast cancer cells, which can be reverted by E4BP4 silencing.
NFIL3 plays a neuroprotective role in neurons and constitutes a potential therapeutic target for neurodegeneration.
Data indicate that E4BP4 can inhibit CD40L (show CD40LG Antibodies) expression through epigenetic modifications in the promoter region of CD40L (show CD40LG Antibodies).
NFIL3 alters cancer cell behavior and FOXO (show FOXO3 Antibodies) function by acting on chromatin to restrict the menu of FOXO (show FOXO3 Antibodies) target genes
The clock-regulated and immune system modulator transcription factor E4BP4/ NFIL3 likely regulates the expression of both appb in zebrafish and APP (show APP Antibodies) in humans.
G9a (show EHMT2 Antibodies) mediates E4BP4-dependent suppression of hepatic Fgf21 (show FGF21 Antibodies) by enhancing histone methylation (H3K9me2) of the Fgf21 (show FGF21 Antibodies) promoter
Conclude that E4BP4 plays as a survival factor in heart and E4BP4 is essential for proper embryonic heart development.
This report demonstrates that GC-mediated upregulation of the bZIP transcriptional repressor gene, E4BP4, is dependent on [Ca2 (show CA2 Antibodies)+]i levels, and correlates with GC-evoked apoptosis of GC-sensitive CEM-C7-14 cells.
Study shows that Nfil3 is enriched in the myeloid compartment of adult zebrafish including eosinophils.
conclude that E4BP4/NIFL3 plays as a survival factor in heart and E4BP4 is essential for proper embryonic heart development.
removal of NFIL3 in vivo does not recapitulate the regeneration-promoting effects that were previously observed in vitro.
These findings establish that NFIL3 directs the differentiation of a committed innate lymphoid cell precursor.
These data identify an IL-27 (show IL27 Antibodies)/NFIL3 signalling axis as a key regulator of effector T-cell responses via induction of Tim-3 (show HAVCR2 Antibodies), IL-10 (show IL10 Antibodies) and T-cell dysfunction.
establish NFIL3 as a key regulator of common helper-like innate lymphoid cells progenitors as they emerge during early lymphopoiesis
Iso-mediated induction of Nfil3 in osteoblasts regulates the expression of Ptgs2 (show PTGS2 Antibodies) by driving the expression of circadian clock genes
E4BP4 plays a crucial role in glucocorticoid -evoked apoptosis of osteoblasts by enabling induction of Bim (show BCL2L11 Antibodies)
Nfil3 is a key regulator of the development of innate lymphoid cell subsets essential for immune protection in the lung and gut (show GUSB Antibodies).
Nfil3 is critical for normal development of gut (show GUSB Antibodies)-associated type 3 innate lymphoid cells. Nfil3 deficiency severely compromises intestinal innate immune defense against acute bacterial infection with Citrobacter rodentium and Clostridium difficile.
signals transmitted by Ly49H (show KLRA8 Antibodies) and proinflammatory cytokines are sufficient to promote NK cell differentiation in the absence of Nfil3.
E4bp4 is required for commitment to the natural killer (NK) lineage and promotes NK development by directly regulating the expression of the downstream transcription factors Eomes and Id2.
Expression of interleukin-3 (IL3\; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995
nuclear factor, interleukin 3 regulated
, nuclear factor interleukin-3-regulated protein-like
, E4 promoter-binding protein 4
, interleukin-3 promoter transcriptional activator
, interleukin-3-binding protein 1
, nuclear factor interleukin 3 regulated protein
, nuclear factor interleukin-3-regulated protein
, transcriptional activator NF-IL3A
, E4 promoter binding-protein 4
, E4 binding protein 4-1
, bZIP protein E4BP4
, cE4BP4 protein
, embryo implantation-related NFIL3/E4BP4-like transcription factor