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anti-Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) Antibodies

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Additionally we are shipping NFE2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFE2 4778 Q16621
NFE2 18022 Q07279
NFE2 366998 Q6AYT2
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Top anti-NFE2 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NFE2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB NFE2 Antibody (C-term) (ABIN657484) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the NFE2 antibody detected the NFE2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NFE2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-NFE2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB Western Blot analysis of NFE2 expression in transfected 293T cell line by NFE2 monoclonal antibody (M01), clone 2C6. Lane 1: NFE2 transfected lysate(41.5 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

NFE2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-NFE2 Antibodies

  1. Human Polyclonal NFE2 Primary Antibody for WB - ABIN657484 : Wang, Schwemmers, Hexner, Pahl: AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2. in Blood 2010 (PubMed)
    Show all 5 references for ABIN657484

  2. Cow (Bovine) Polyclonal NFE2 Primary Antibody for WB - ABIN2787523 : McCormack, Hall, Schoenwaelder, Zhao, Ellis, Prentice, Clarke, Slater, Salmon, Jackson, Jane, Curtis: A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis. in Blood 2006 (PubMed)

More Antibodies against NFE2 Interaction Partners

Human Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) interaction partners

  1. assessment of NF-E2 and NGFR (show NGFR Antibodies) expression may provide additional support in reaching a correct diagnosis in discriminating polycythemia vera (show IGF2BP3 Antibodies) from prefibrotic/fibrotic primary myelofibrosis and essential thrombocythemia

  2. The genes BCL6 (show BCL6 Antibodies), NFE2, POU4F2 (show POU4F2 Antibodies) and ELF4 are primary 1,25(OH)2D3 targets in THP-1 (show GLI2 Antibodies) cells

  3. the RUNX1 (show RUNX1 Antibodies) target NF-E2 is part of the molecular network by which RUNX1 (show RUNX1 Antibodies) regulates platelet biogenesis and function in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia

  4. A functional link among the erythroid transcription factors GATA-1 (show GATA1 Antibodies)/NF-E2, miR (show MLXIP Antibodies)-199b-5p in erythropoiesis.

  5. NF-E2 immunohistochemistry and analysis of the proportion of nuclear positive erythroblasts of all erythroid precursor cells can help to distinguish between ET and PMF even in early stages of the diseases.

  6. NFE-2 transgene mediates the expression of interleukin 8 (show IL8 Antibodies) in myeloproliferative neoplasms, thereby contributing to myeloproliferative neoplasm pathology.

  7. Findings suggest a model whereby ROCK inhibition drives polyploidization, DMS growth and proplatelet formation late in megakaryocyte maturation through downregulation of MYC (show MYC Antibodies) and NFE2 expression.

  8. IFN-gamma modulates NF-kappaB/c-Jun to antagonize activin A-mediated NF-E2 transcriptional activity on erythroid cell globin gene expression.

  9. RUNX1 (show RUNX1 Antibodies) and NF-E2 are overexpressed in polycythemic patients of diverse phenotypes and molecular causes

  10. Here we demonstrate that NF-E2 is mislocalized in prefibrotic primary myelofibrosis cells and that aberrant NF-E2 localization discriminates statistically highly significantly between essential thrombocytthemia and that disease.

Mouse (Murine) Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) interaction partners

  1. A novel murine model may excellently describe the deleterious impact of sustained chronic NF-E2 overexpression during uncontrolled chronic inflammation upon the hematopoietic system--the development of clonal myeloproliferation.

  2. Although none of the parameters measured were different between the NF-E2 deficient and control mice, an increase in calcium (21%) and an increase in the mineral/matrix ratio (32%) was observed in GATA-1 (show GATA1 Antibodies) deficient mice.

  3. By activating genes in megakaryocytes that mediate platelet production and function, NF-E2 p45 determines the quantity and quality of platelets.

  4. maintaining expression of intestinal epithelial cell prohibitin (show PHB Antibodies) reduces the severity of inflammation and increases colonic levels of the antioxidants HO-1 (show HMOX1 Antibodies) and NQO-1 (show NQO1 Antibodies) via a mechanism independent of Nfe2

  5. These findings demonstrate that a combination of p45NF-E2, Maf (show MAF Antibodies) G, and Maf (show MAF Antibodies) K is a key determinant of both megakaryopoiesis and thrombopoiesis.

  6. Loss of p45 NF-E2 leads to a 2-fold increase in serum erythropoietin (show EPO Antibodies) & increased splenic erythropoiesis. Erythroid cells were arrested at the G(1) stage of cell cycle.

  7. Nfe2 modulates JunD (show JUND Antibodies) binding to the Gcm1 (show GCM1 Antibodies) promoter via acetylation

  8. studies identify a novel function of p45NF-E2 during placental development: in trophoblast cells, p45NF-E2 represses Gcm1 (show GCM1 Antibodies) and syncytiotrophoblast formation via acetylation

  9. NLS (show ALDH1A2 Antibodies)-dependent nuclear import of p45 NF-E2 is important for platelet development

  10. USF and NF-E2 cooperate to regulate the recruitment and activity of RNA polymerase II in the beta-globin (show HBB Antibodies) gene locus.

NFE2 Antigen Profile

Protein Summary

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Gene names and symbols associated with NFE2

  • nuclear factor (erythroid-derived 2), 45kDa (NFE2) antibody
  • nuclear factor, erythroid 2 (NFE2) antibody
  • nuclear factor, erythroid derived 2 (Nfe2) antibody
  • 45kDa antibody
  • NF-E2 antibody
  • p45 antibody
  • p45nf-e2 antibody
  • p45NFE2 antibody

Protein level used designations for NFE2

leucine zipper protein NF-E2 , nuclear factor, erythroid derived 2 , nuclear factor, erythroid-derived 2 45 kDa subunit , p45 NF-E2 , transcription factor NF-E2 45 kDa subunit , nuclear factor (erythroid-derived 2), 45kD , nuclear factor (erythroid-derived 2), 45kDa , nuclear factor, erythroid derived 2, 45 kDa

GENE ID SPECIES
486495 Canis lupus familiaris
514006 Bos taurus
4778 Homo sapiens
18022 Mus musculus
366998 Rattus norvegicus
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