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NFE2L3 encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. Additionally we are shipping NFE2L3 Antibodies (36) and many more products for this protein.
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findings reveal FBW7 (show FBXW7 Proteins) and GSK3 as novel regulators of the NFE2L3 transcription factor and a potential mechanism by which FBW7 (show FBXW7 Proteins) might regulate detoxification and the cellular response to stress
17beta-Estradiol treatment significantly increased but VC or Res decreased Nrf3 mRNA and protein expression levels.
Nrf3 is a negative regulator of ARE-mediated gene expression of NQO1 (show NQO1 Proteins)
NRF3 is highly expressed in primary placental cytotrophoblasts
Nrf3 is an N-glycosylated protein associated with the endoplasmic reticulum
Pla2g7 (show Lp-PLA2 Proteins) plays a crucial physiological role in smooth muscle cell differentiation from stem cells, and interactions between Nrf3 and Pla2g7 (show Lp-PLA2 Proteins) are essential.
Contrary to wild-type mice, Nrf3-null animals are highly susceptible to B (show TDO2 Proteins)[a]P, exhibiting significantly increased mortality. Pathology analysis revealed a high incidence of T-cell lymphoblastic lymphoma in B[a]P-treated Nrf3(-/-) mice.
Demonstrate that Nrf3 has a crucial role in smooth muscle cell differentiation from embryonic stem cells.
Data show that Nrf3 null mice develop normally with no obvious phenotypic differences compared to wild-type animals, that they are fertile, and that gross anatomy as well as behavior appear normal.
data are presented suggesting that the NHB2 sequence in mouse Nrf3 may regulate the topology of the transcription factor within the ER membrane
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
nuclear factor erythroid 2-related factor 3
, NF-E2-related factor 3
, NFE2-related factor 3
, nuclear factor (erythroid-derived 2)-like 3
, nuclear factor, erythroid derived 2, like 3
, nuclear factor-erythroid 2 p45-related factor 3
, nuclear factor-erythroid 2-related factor 3
, nuclear factor erythroid 2-like 3