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Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein Proteins (NFATC2IP)

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Additionally we are shipping Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NFATC2IP 18020 O09130
NFATC2IP 84901 Q8NCF5
NFATC2IP 308983 Q6AYG7
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Top Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,131.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,151.50
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,213.83
Details

NFATC2IP Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP) Interaction Partners

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP) interaction partners

  1. results indicate that RANKL (show TNFSF11 Proteins) signaling down regulates NIP45 expression and that NIP45 is a negative regulator of osteoclast differentiation

  2. This finding highlights a possible role of the RENi proteins in the modulation of Ubc9-mediated poly-SUMO formation.

  3. NIP45 promotes robust cytokine expression in vivo, which is required for the efficient handling of parasites, acting as a molecular rheostat serving to amplify the type-2 immune response.

  4. Data report a role for arginine methylation of NIP45 in regulating cytokine gene transcription in the T helper lymphocyte.

  5. TRAF1 (show TRAF1 Proteins) limit the induction of Th2 responses by decreasing NIP45 concentration to the nucleus down-regulating the expression of NIP45-dependent IL-4 (show IL4 Proteins) gene transcription.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP) interaction partners

  1. ZBTB25 (show ZBTB25 Proteins) functions as a negative regulator of nuclear factor of activated T cells (NF-AT (show NFATC3 Proteins)) activation, such that RNA interference mediated knockdown resulted in enhanced activation of target genes.

Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP) Protein Profile

Protein Summary

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter\; this leads to enhancement of histone H4 'Arg-3'- methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down- regulates formation of poly-SUMO chains by UBE2I/UBC9.

Gene names and symbols associated with NFATC2IP

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein (nfatc2ip)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein (NFATC2IP)
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein (Nfatc2ip)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein (Nfatc2ip)
  • D7Ertd304e protein
  • ESC2 protein
  • NFATC2IP protein
  • NIP45 protein
  • RAD60 protein
  • wu:fj84d09 protein

Protein level used designations for NFATC2IP

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein , NFATC2-interacting protein , 45 kDa NF-AT-interacting protein , 45 kDa NFAT-interacting protein , nuclear factor of activated T-cells, cytoplasmic 2 interacting protein , nuclear factor of activated T-cells, cytoplasmic 2-interacting protein

GENE ID SPECIES
337574 Danio rerio
505998 Bos taurus
607936 Canis lupus familiaris
704878 Macaca mulatta
743214 Pan troglodytes
18020 Mus musculus
84901 Homo sapiens
308983 Rattus norvegicus
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