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Nuclear Protein 1 Proteins (NUPR1)

Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. Additionally we are shipping Nuclear Protein 1 Antibodies (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse NUPR1 NUPR1 56312 Q9WTK0
Human NUPR1 NUPR1 26471 O60356
NUPR1 113900  
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Top Nuclear Protein 1 Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Rat His tag 1 mg Log in to see 56 to 66 Days
$2,113.83
Details

NUPR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

More Proteins for Nuclear Protein 1 (NUPR1) Interaction Partners

Mouse (Murine) Nuclear Protein 1 (NUPR1) interaction partners

  1. Nupr1 acts as a gene modifier of the effect of Kras(G12D)-induced senescence by regulating Dnmt1 (show DNMT1 Proteins) expression and consequently genome-wide levels of DNA methylation (show HELLS Proteins).

  2. Hepatitis B virus X (HBx) protein can modulate NUPR1 expression through the Smad4 (show SMAD4 Proteins) pathway and NUPR1 has a role in hepatocellular carcinoma progression.

  3. Data indicate that heat shock protein 70 (Hsp70 (show HSP70 Proteins)) is higher in nuclear protein 1 (Nupr1+/-) haplodeficient mice, concomitant with improved insulin (show INS Proteins) sensitivity.

  4. Nupr1 aids oncogenic Kras to bypass senescence in a manner that cooperatively promotes pancreas intraepithelial neoplasia formation.

  5. data shows that p8 deficiency increases ROS (show ROS1 Proteins) and subsequently the expression of anti-oxidative enzymes, such as HO-1 (show HMOX1 Proteins), suggesting an involvement in the anti-oxidative defense.

  6. According to Nupr1 status, KIC mice develop tumours that phenocopy human classical or QM-PDAC, respectively, and present differential drug sensitivity, thus becoming attractive models for preclinical drug trials.

  7. Nupr1 expression is required for IL-1beta-mediated expression of MMP-13. (show MMP13 Proteins)

  8. Inhibition of NUPR1 expression or activity has the potential to protect against the metabolic defects associated with obesity and type 2 diabetes.

  9. a NUPR1/RELB/IER3 stress-related pathway that is required for oncogenic Kras(G12D)-dependent transformation of the pancreas.

  10. progressive PPARalpha (show PPARA Proteins)- and p8-mediated ER stress contribute to the hepatocarcinogenesis in ACOX1 (show ACOX1 Proteins)(-/-) mice

Human Nuclear Protein 1 (NUPR1) interaction partners

  1. Nupr1 acts as a gene modifier of the effect of Kras(G12D)-induced senescence by regulating Dnmt1 (show DNMT1 Proteins) expression and consequently genome-wide levels of DNA methylation (show HELLS Proteins).

  2. Hepatitis B virus X (HBx) protein can modulate NUPR1 expression through the Smad4 (show SMAD4 Proteins) pathway and NUPR1 has a role in hepatocellular carcinoma progression.

  3. Mitochondrial respiratory defects and subsequent retrograde signaling, particularly the NUPR1-granulin (show GRN Proteins) pathway, play pivotal roles in liver cancer progression

  4. Functional characterization of NUPR1L as a new p53 (show TP53 Proteins)-induced gene, which negatively regulates the protumoral factor NUPR1.

  5. Knockdown of Nupr1 inhibited the proliferation and migration of HepG2 hepatocellular carcinoma cells

  6. NUPR1 has been conserved throughout evolution, and over time it has undergone duplications and transpositions to form other transcriptional regulators.

  7. Increase of NUPR1 protein expression is associated with endometrial cancer invasion.

  8. P8 and MEG3 mRNA levels were significantly lower in nonfunctioning and corticotroph adenomas compared with normal pituitary.

  9. The Nupr1 protein bound to chemically-damaged-DNA with a slightly larger affinity (0.4 microM), but in an enthalpically-driven process. Nupr1 showed different interacting regions in the formed complexes with Nupr1 or DNA

  10. Stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 (show MMP13 Proteins) expression in human articular chondrocytes.

Nuclear Protein 1 (NUPR1) Protein Profile

Protein Summary

Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype.

Gene names and symbols associated with Nuclear Protein 1 Proteins (NUPR1)

  • nuclear protein, transcriptional regulator, 1 (NUPR1)
  • nuclear protein transcription regulator 1 (Nupr1)
  • nuclear proten 1 (P8)
  • 2310032H04Rik protein
  • COM1 protein
  • Nupr1 protein
  • P8 protein

Protein level used designations for Nuclear Protein 1 Proteins (NUPR1)

p8 protein , nuclear protein 1 , protein p8 , candidate of metastasis 1 , nuclear protein, transcriptional regulator, 1

GENE ID SPECIES
736758 Pan troglodytes
56312 Mus musculus
26471 Homo sapiens
113900 Rattus norvegicus
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