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NXF2 is one of a family of nuclear RNA export factor genes. Additionally we are shipping Nuclear RNA Export Factor 2 Antibodies (15) and Nuclear RNA Export Factor 2 Proteins (3) and many more products for this protein.
Low NXF2 expression is associated with leukemia.
Data do not support role for NXF2 in male infertility.
Exhibits mRNA export activity similar to that of Tip-associated protein/NXF1 (show NXF1 ELISA Kits).
The NXF2 protein is found in the nucleus, the nuclear envelope and cytoplasm, and is an active mRNA export receptor.
Results suggest that NXF2, a nucleo-cytoplasmic mRNA transporter, plays additional roles in the cytoplasmic localization of mRNAs through interactions with cytoplasmic motor proteins.
FMRP (show FMR1 ELISA Kits) and Nxf2 associate with and destabilize Nxf1 (show NXF1 ELISA Kits) mRNA in neuronal cells.
These studies demonstrate that Nxf2 plays a dual function in spermatogenesis: regulation of meiosis and maintenance of spermatogonial stem cells.
Involved in the export of mRNA from the nucleus to the cytoplasm.
TAP-like protein 2
, cancer/testis antigen 39
, t-complex protein 11 homolog
, nuclear RNA export factor 2B
, nuclear RNA export factor 2