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anti-Nuclear Receptor Coactivator 2 (NCOA2) Antibodies

The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Additionally we are shipping NCOA2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NCOA2 2268 P09769
NCOA2 17978 Q61026
NCOA2 83724 Q9WUI9
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Top anti-NCOA2 Antibodies at

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with TSA 400... Immunohistochemistry analysis of paraffin-embedded human breast carcin... 100 μg Log in to see 2 to 3 Days
Dog Mouse Un-conjugated IF, WB Western blot analysis of TIF2 on a Jurkat cell lysate (Human T-cell le... Immunofluorescence staining of C3H/10T1/2 cells (Mouse embryonic fibro... 50 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated IHC, ELISA   100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
Human Goat Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated DB, WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
Human Mouse Un-conjugated DB, WB   50 μg Log in to see 8 to 10 Days

NCOA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NCOA2 Antibodies

  1. Human Polyclonal NCOA2 Primary Antibody for EIA, WB - ABIN493179 : Mukherjee, Soyal, Fernandez-Valdivia, Gehin, Chambon, Demayo, Lydon, OMalley: Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. in Molecular and cellular biology 2006 (PubMed)
    Show all 5 references for ABIN493179

  2. Dog (Canine) Monoclonal NCOA2 Primary Antibody for IF, WB - ABIN968296 : Heery, Kalkhoven, Hoare, Parker: A signature motif in transcriptional co-activators mediates binding to nuclear receptors. in Nature 1997 (PubMed)
    Show all 4 references for ABIN968296

  3. Chicken Polyclonal NCOA2 Primary Antibody for WB - ABIN2780788 : Strehl, Nebral, König, Harbott, Strobl, Ratei, Struski, Bielorai, Lessard, Zimmermann, Haas, Izraeli: ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

  4. Human Polyclonal NCOA2 Primary Antibody for IHC, ELISA - ABIN1450725 : Carapeti, Aguiar, Goldman, Cross: A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia. in Blood 1998 (PubMed)

More Antibodies against NCOA2 Interaction Partners

Human Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. Report NcoA2-regulation of the AhR (show AHR Antibodies)-ARNT (show ARNT Antibodies)-HIF-1a (show HIF1A Antibodies) interaction.

  2. Data suggest that LRH1/NR5A2 (show NR5A2 Antibodies) (liver receptor homologue-1) exhibits phospholipid-mediated allosteric control of protein-protein binding interface in interactions with TIF2 and SHP (show LAMC1 Antibodies) (co-repressor; small heterodimer partner (show NR0B2 Antibodies) protein).

  3. NCOA2 is a novel negative growth regulatory gene repressing the Wnt/beta-catenin pathway in colorectal cancer, where recurrent fusion with LACTB2 contributes to its disruption.

  4. Suggest a possible association between NCOA2 rs10504473 polymorphism and obesity in Chinese Han population.

  5. miR (show MLXIP Antibodies)-137 has a role in targeting p160 (show MSH6 Antibodies) steroid receptor (show ESR2 Antibodies) coactivators SRC1 (show SRC Antibodies), SRC2, and SRC3 (show NCOA3 Antibodies) and inhibits cell proliferation

  6. results suggest that CCNC (show CCNC Antibodies) temporarily protects SRC-2 against degradation and this event is involved in the transcriptional regulation of SRC-2 cell cycle target genes.

  7. Data suggest that over-stimulating the steroid seceptor coactivators SRC-1 (show SRC Antibodies), SRC-2, and SRC-3 (show NCOA3 Antibodies) oncogenic program can be an effective strategy to kill cancer cells.

  8. we provide evidence for involvement of HCK (show HCK Antibodies) and FGR (show FGR Antibodies) in FCRL4 (show FCRL4 Antibodies)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (show FCRL4 Antibodies) molecule.

  9. SRC-2 is a prominent metabolic coordinator of cancer metastasis.

  10. Because deregulation of endometrial SRC-2 expression has been associated with common gynecological disorders of reproductive-age women, this signaling pathway, involving SRC-2 and PFKFB3 (show PFKFB3 Antibodies).

Mouse (Murine) Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. the expression of MOZ (show MYST3 Antibodies)-TIF2 fusion protein represses the transcription of p16INK4a (show CDKN2A Antibodies) and p19ARF (show CDKN2A Antibodies) and blocks senescence.

  2. findings position SRC-2 as a major regulator of polygenic inputs to metabolic gene regulation and perhaps identify a previously unappreciated model that helps to explain the clinical spectrum of glucose dysregulation

  3. fetal lungs produce signals to initiate labor when mature, and SRC-1 (show NCOA1 Antibodies)/-2-dependent production of SP-A (show SFTPA1 Antibodies) and PAF (show KIAA0101 Antibodies) is crucial for this process

  4. In a murine model, overexpression of NCoA2 in the prostate epithelium resulted in neoplasia.

  5. the PAX3 (show PAX3 Antibodies)-NCOA2 fusion gene has a dual role in the tumorigenesis of rhabdomyosarcoma

  6. Transcription factor 23 (Tcf23 (show TCF23 Antibodies)), a basic-helix-loop-helix transcription factor (show HEY1 Antibodies), is a new progesterone-induced target gene that requires SRC-2 for full induction.

  7. SRC-2 is a transcriptional coactivator for BMAL1 (show ARNTL Antibodies):CLOCK. Ablation of SRC-2 disrupts the central clock.

  8. SRC-2 is critical to transcriptional control modulated by MEF2 (show MEF2C Antibodies), GATA-4 (show GATA4 Antibodies), and Tbx5 (show TBX5 Antibodies), thereby enhancing gene expression associated with cardiac growth.

  9. SRC2 regulates anxiety response with SRC2(-/-) females showing decreased anxiety in novel environments.

  10. Our results indicate that SRC-2 is involved in maintenance of the steady-state adult heart transcriptional profile, with its ablation inducing transcriptional changes that mimic a stressed heart.

Zebrafish Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. The tif2 is involved in embryogenesis and in primitive hematopoiesis. tif2-knockdown zebrafish embryos are smaller than controls.

NCOA2 Antigen Profile

Protein Summary

The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997

Gene names and symbols associated with NCOA2

  • nuclear receptor coactivator 2 (NCOA2) antibody
  • nuclear receptor coactivator 2 (ncoa2) antibody
  • feline Gardner-Rasheed sarcoma viral oncogene homolog (FGR) antibody
  • nuclear receptor coactivator 2 (Ncoa2) antibody
  • 9530095N19 antibody
  • bHLHe75 antibody
  • c-fgr antibody
  • c-src2 antibody
  • D1Ertd433e antibody
  • GRIP-1 antibody
  • Grip1 antibody
  • KAT13C antibody
  • NCoA-2 antibody
  • NCOA2 antibody
  • ncoa2-A antibody
  • p55-Fgr antibody
  • p55c-fgr antibody
  • p58-Fgr antibody
  • p58c-fgr antibody
  • SRC-2 antibody
  • SRC2 antibody
  • TIF-2 antibody
  • Tif2 antibody
  • wu:fc41a10 antibody
  • wu:fe26a11 antibody
  • XTIF2 antibody

Protein level used designations for NCOA2

nuclear receptor coactivator 2 , Transcriptional intermediary factor 2 , nuclear receptor coactivator 2-like , Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog , c-fgr protooncogene , c-src-2 proto-oncogene , p55-c-fgr protein , proto-oncogene c-Fgr , proto-oncogene tyrosine-protein kinase FGR , tyrosine-protein kinase Fgr , v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog , class E basic helix-loop-helix protein 75 , glucocorticoid receptor-interacting protein-1 , hTIF2 , transcriptional intermediary factor 2 , NCoA-2 , TIF2/GRIP-1 , glucocorticoid receptor interacting protein 1 , glucocorticoid receptor-interacting protein 1 , transcriptional intermediary factor-2 , grip1 , src2 , steroid receptor coactivator 2

464226 Pan troglodytes
693455 Macaca mulatta
100028678 Monodelphis domestica
100051656 Equus caballus
100089041 Ornithorhynchus anatinus
100216190 Xenopus (Silurana) tropicalis
100220180 Taeniopygia guttata
100409563 Callithrix jacchus
100458310 Pongo abelii
100468579 Ailuropoda melanoleuca
100567715 Anolis carolinensis
100594525 Nomascus leucogenys
2268 Homo sapiens
10499 Homo sapiens
17978 Mus musculus
83724 Rattus norvegicus
394405 Xenopus laevis
420176 Gallus gallus
486989 Canis lupus familiaris
100135658 Sus scrofa
508162 Bos taurus
81884 Danio rerio
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