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Nuclear Receptor Coactivator 2 (NCOA2) ELISA Kits

The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Additionally we are shipping NCOA2 Antibodies (60) and NCOA2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human NCOA2 NCOA2 2268 P09769
Anti-Mouse NCOA2 NCOA2 17978 Q61026
Anti-Rat NCOA2 NCOA2 83724 Q9WUI9
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More ELISA Kits for NCOA2 Interaction Partners

Human Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. Report NcoA2-regulation of the AhR (show AHR ELISA Kits)-ARNT (show ARNT ELISA Kits)-HIF-1a (show HIF1A ELISA Kits) interaction.

  2. Data suggest that LRH1/NR5A2 (show NR5A2 ELISA Kits) (liver receptor homologue-1) exhibits phospholipid-mediated allosteric control of protein-protein binding interface in interactions with TIF2 and SHP (show LAMC1 ELISA Kits) (co-repressor; small heterodimer partner (show NR0B2 ELISA Kits) protein).

  3. NCOA2 is a novel negative growth regulatory gene repressing the Wnt/beta-catenin pathway in colorectal cancer, where recurrent fusion with LACTB2 contributes to its disruption.

  4. Suggest a possible association between NCOA2 rs10504473 polymorphism and obesity in Chinese Han population.

  5. miR (show MLXIP ELISA Kits)-137 has a role in targeting p160 (show MSH6 ELISA Kits) steroid receptor (show ESR2 ELISA Kits) coactivators SRC1 (show SRC ELISA Kits), SRC2, and SRC3 (show NCOA3 ELISA Kits) and inhibits cell proliferation

  6. results suggest that CCNC (show CCNC ELISA Kits) temporarily protects SRC-2 against degradation and this event is involved in the transcriptional regulation of SRC-2 cell cycle target genes.

  7. Data suggest that over-stimulating the steroid seceptor coactivators SRC-1 (show SRC ELISA Kits), SRC-2, and SRC-3 (show NCOA3 ELISA Kits) oncogenic program can be an effective strategy to kill cancer cells.

  8. we provide evidence for involvement of HCK (show HCK ELISA Kits) and FGR (show FGR ELISA Kits) in FCRL4 (show FCRL4 ELISA Kits)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (show FCRL4 ELISA Kits) molecule.

  9. SRC-2 is a prominent metabolic coordinator of cancer metastasis.

  10. Because deregulation of endometrial SRC-2 expression has been associated with common gynecological disorders of reproductive-age women, this signaling pathway, involving SRC-2 and PFKFB3 (show PFKFB3 ELISA Kits).

Mouse (Murine) Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. the expression of MOZ-TIF2 fusion protein represses the transcription of p16INK4a and p19ARF and blocks senescence.

  2. findings position SRC-2 as a major regulator of polygenic inputs to metabolic gene regulation and perhaps identify a previously unappreciated model that helps to explain the clinical spectrum of glucose dysregulation

  3. fetal lungs produce signals to initiate labor when mature, and SRC-1 (show NCOA1 ELISA Kits)/-2-dependent production of SP-A (show SFTPA1 ELISA Kits) and PAF (show KIAA0101 ELISA Kits) is crucial for this process

  4. In a murine model, overexpression of NCoA2 in the prostate epithelium resulted in neoplasia.

  5. the PAX3 (show PAX3 ELISA Kits)-NCOA2 fusion gene has a dual role in the tumorigenesis of rhabdomyosarcoma

  6. Transcription factor 23 (Tcf23 (show TCF23 ELISA Kits)), a basic-helix-loop-helix transcription factor (show HEY1 ELISA Kits), is a new progesterone-induced target gene that requires SRC-2 for full induction.

  7. SRC-2 is a transcriptional coactivator for BMAL1 (show ARNTL ELISA Kits):CLOCK. Ablation of SRC-2 disrupts the central clock.

  8. SRC-2 is critical to transcriptional control modulated by MEF2 (show MEF2C ELISA Kits), GATA-4 (show GATA4 ELISA Kits), and Tbx5 (show TBX5 ELISA Kits), thereby enhancing gene expression associated with cardiac growth.

  9. SRC2 regulates anxiety response with SRC2(-/-) females showing decreased anxiety in novel environments.

  10. Our results indicate that SRC-2 is involved in maintenance of the steady-state adult heart transcriptional profile, with its ablation inducing transcriptional changes that mimic a stressed heart.

Zebrafish Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. The tif2 is involved in embryogenesis and in primitive hematopoiesis. tif2-knockdown zebrafish embryos are smaller than controls.

NCOA2 Antigen Profile

Antigen Summary

The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997

Gene names and symbols associated with NCOA2

  • nuclear receptor coactivator 2 (NCOA2) antibody
  • nuclear receptor coactivator 2 (ncoa2) antibody
  • feline Gardner-Rasheed sarcoma viral oncogene homolog (FGR) antibody
  • nuclear receptor coactivator 2 (Ncoa2) antibody
  • 9530095N19 antibody
  • bHLHe75 antibody
  • c-fgr antibody
  • c-src2 antibody
  • D1Ertd433e antibody
  • GRIP-1 antibody
  • Grip1 antibody
  • KAT13C antibody
  • NCoA-2 antibody
  • NCOA2 antibody
  • ncoa2-A antibody
  • p55-Fgr antibody
  • p55c-fgr antibody
  • p58-Fgr antibody
  • p58c-fgr antibody
  • SRC-2 antibody
  • SRC2 antibody
  • TIF-2 antibody
  • Tif2 antibody
  • wu:fc41a10 antibody
  • wu:fe26a11 antibody
  • XTIF2 antibody

Protein level used designations for NCOA2

nuclear receptor coactivator 2 , Transcriptional intermediary factor 2 , nuclear receptor coactivator 2-like , Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog , c-fgr protooncogene , c-src-2 proto-oncogene , p55-c-fgr protein , proto-oncogene c-Fgr , proto-oncogene tyrosine-protein kinase FGR , tyrosine-protein kinase Fgr , v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog , class E basic helix-loop-helix protein 75 , glucocorticoid receptor-interacting protein-1 , hTIF2 , transcriptional intermediary factor 2 , NCoA-2 , TIF2/GRIP-1 , glucocorticoid receptor interacting protein 1 , glucocorticoid receptor-interacting protein 1 , transcriptional intermediary factor-2 , grip1 , src2 , steroid receptor coactivator 2

464226 Pan troglodytes
693455 Macaca mulatta
100028678 Monodelphis domestica
100051656 Equus caballus
100089041 Ornithorhynchus anatinus
100216190 Xenopus (Silurana) tropicalis
100220180 Taeniopygia guttata
100409563 Callithrix jacchus
100458310 Pongo abelii
100468579 Ailuropoda melanoleuca
100567715 Anolis carolinensis
100594525 Nomascus leucogenys
2268 Homo sapiens
10499 Homo sapiens
17978 Mus musculus
83724 Rattus norvegicus
394405 Xenopus laevis
420176 Gallus gallus
486989 Canis lupus familiaris
100135658 Sus scrofa
508162 Bos taurus
81884 Danio rerio
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