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The protein encoded by NCOA3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. Additionally we are shipping Nuclear Receptor Coactivator 3 Kits (9) and Nuclear Receptor Coactivator 3 Proteins (3) and many more products for this protein.
Showing 10 out of 156 products:
Human Polyclonal NCOA3 Primary Antibody for EIA, WB - ABIN401409
Naeem, Cheng, Zhao, Underhill, Tini, Bedford, Torchia: The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation. in Molecular and cellular biology 2006
Show all 6 references for ABIN401409
Human Monoclonal NCOA3 Primary Antibody for IF, WB - ABIN968367
Anzick, Kononen, Walker, Azorsa, Tanner, Guan, Sauter, Kallioniemi, Trent, Meltzer: AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. in Science (New York, N.Y.) 1997
Show all 5 references for ABIN968367
Human Polyclonal NCOA3 Primary Antibody for WB - ABIN1881566
Cai, Shames, Raso, Xie, Kim, Pollack, Girard, Sullivan, Gao, Peyton, Nanjundan, Byers, Heymach, Mills, Gazdar, Wistuba, Kodadek, Minna: Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. in Cancer research 2010
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Human Monoclonal NCOA3 Primary Antibody for WB - ABIN2869357
Zheng, Wu, Smith, OMalley: Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. in Molecular and cellular biology 2005
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Human Monoclonal NCOA3 Primary Antibody for ELISA, WB - ABIN968949
Pu, Ye, Spitz, Wang, Gu, Lippman, Hildebrandt, Hong, Minna, Roth, Yang, Wu: Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012
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Human Monoclonal NCOA3 Primary Antibody for ELISA, WB - ABIN969309
Rangel, Torabian, Shaikh, Nosrati, Baehner, Haqq, Leong, Miller, Sagebiel, Kashani-Sabet: Prognostic significance of nuclear receptor coactivator-3 overexpression in primary cutaneous melanoma. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006
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Human Polyclonal NCOA3 Primary Antibody for IHC, WB - ABIN2779677
Luo, Xie, Liu, Chen, Liu, Wu, Kung, Zeng, Guan: Protein expression and amplification of AIB1 in human urothelial carcinoma of the bladder and overexpression of AIB1 is a new independent prognostic marker of patient survival. in International journal of cancer. Journal international du cancer 2008
Total SRC3 is selectively found at enhancer regions.
The transcriptional coactivator SRC-3.
The aim of this study was to investigate the expression of AIB1 in human esophageal squamous cell carcinoma and its correlation with Ki67 (show MKI67 Antibodies) expression.
NCOA3 polymorphisms might influence the risk of dyslipidemia and serum lipid levels in Chinese Han population.
miR (show MLXIP Antibodies)-137 has a role in targeting p160 (show MSH6 Antibodies) steroid receptor (show ESR2 Antibodies) coactivators SRC1 (show SRC Antibodies), SRC2 (show NCOA2 Antibodies), and SRC3 and inhibits cell proliferation
AIB1 promotes gastric cancer cell proliferation, survival and invasiveness through modulating major signaling pathways such as ErbB (show EGFR Antibodies) and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathways. Findings suggest that AIB1 plays an important role in the pathogenesis of gastric cancer.
ER-alpha (show ESR1 Antibodies), SRC-3, and p300 (show EP300 Antibodies) form an active protein complex on estrogen response element-DNA.
NCOA3 is subject to a cis (show CISH Antibodies)-acting expression quantitative trait locus in articular cartilage, which correlates with the osteoarthritis association signal and with the OA-associated allele of the SNP rs116855380, which is located 10.3 kb upstream of NCOA3.
we describe a TR-FRET assay that monitors the interaction of the estrogen receptor (ER) alpha (show ESR1 Antibodies) ligand binding domain (labeled with a terbium chelate via a streptavidin-biotin interaction) with a sequence of coactivator protein SRC3
NCOA3 upregulates mucin 1 (show MUC1 Antibodies) and 4 via transcriptional and post-translational changes in pancreatic cancer.
SRC-1 (show NCOA1 Antibodies)/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (show SLC12A3 Antibodies)-like abnormalities in the hearts of newborn and adult mice.
SRC-3 is a target for inhibiting aggressive prostate cancer containing neuroendocrine tumor cells.
Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC3 knockout mice.
The p/CIP gene regulatory network identifies various feed-forward modules including one in which p/CIP activates members of the extended pluripotency network, demonstrating that p/CIP is a component of this extended network.
Loss of SRC3 also shows sex differences in anxiety and exploratory behaviors.
IRS1 (show IRS1 Antibodies) levels are significantly increased in mouse cell lines representing fat and muscle lineages with p/CIP and SRC-1 (show NCOA1 Antibodies) deletions and in white adipose tissue and skeletal muscle of knockout mice.
Data show that knockdown of nuclear receptor coactivator 3 (Ncoa3) not only compromises the expression of pluripotency markers but also impairs in vitro and in vivo differentiation potential of embryonic stem cells.
Ncoa3, an essential coactivator, is required to mediate Esrrb function in embryonic stem cells.
A previously unknown function of SRC-3 in the control of endothelial cell phenotypes in vitro and neogenesis and physiologic wound healing in vivo is shown.
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
nuclear receptor coactivator 3
, CBP-interacting protein
, amplified in breast cancer 1 protein
, class E basic helix-loop-helix protein 42
, receptor-associated coactivator 3
, steroid receptor coactivator protein 3
, thyroid hormone receptor activator molecule 1
, steroid receptor coactivator 3
, amplified in breast cancer-1 protein homolog
, retinoid X receptor-interacting coactivator xSRC-3