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anti-Nuclear Receptor Coactivator 6 (NCOA6) Antibodies

The protein encoded by NCOA6 is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. Additionally we are shipping NCOA6 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NCOA6 23054 Q14686
Anti-Mouse NCOA6 NCOA6 56406  
Anti-Rat NCOA6 NCOA6 116464  
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Top anti-NCOA6 Antibodies at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to NCOA6 on HeLa cell (antibody concentration 10 µg/mL). NCOA6 monoclonal antibody (M01), clone 2D7 Western Blot analysis of NCOA6 expression in HeLa NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to NCOA6 on HeLa cell. [antibody concentration 10 ug/ml] NCOA6 monoclonal antibody (M01), clone 2D7 Western Blot analysis of NCOA6 expression in Hela S3 NE . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, IP, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated IF, ELISA, WB   100 μg Log in to see 11 to 16 Days
$553.14
Details
Human Mouse Un-conjugated ELISA   50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$815.83
Details
Human Rabbit Un-conjugated IP, WB   100 μg Log in to see 8 to 10 Days
$815.83
Details
Human Mouse Un-conjugated IF, ELISA, WB   100 μg Log in to see 6 to 8 Days
$487.30
Details

NCOA6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-NCOA6 Antibodies

  1. Human Monoclonal NCOA6 Primary Antibody for IF, WB - ABIN393600 : Kim, Choi, Jin, Kang, Choi, Jeon, Lee, Kim, Kim, Kim, Son, Jung, Park: Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study. in Molecular carcinogenesis 2010 (PubMed)
    Show all 5 references for ABIN393600

More Antibodies against NCOA6 Interaction Partners

Human Nuclear Receptor Coactivator 6 (NCOA6) interaction partners

  1. The retinoid x receptor (show RXRB Antibodies) does not interact with the NR box-1 of ASC-2, but functions as an allosteric activator of LXR (show NR1H3 Antibodies) binding to NR box-2 of ASC-2.

  2. diverse physiological function of NCOA6 may be mediated by multiple isoforms expressed in different tissues and localized in different subcellular compartments

  3. NCOA6 is responsible for the synergistic activation of CYP2C9 (show CYP2C9 Antibodies) by HNF4alpha (show HNF4A Antibodies) and pregnane X receptor (show NR1I2 Antibodies) and NCOA6 differentially regulates CYP2C9 (show CYP2C9 Antibodies) and CYP3A4 (show CYP3A4 Antibodies) gene expression though both the genes are regulated by the same nuclear receptors.

  4. we show that ASC-2 belongs to a steady-state complex of approximately 2 MDa (ASC-2 complex [ASCOM]) in HeLa nuclei. ASCOM contains retinoblastoma-binding protein RBQ-3 (show RBBP5 Antibodies), alpha/beta-tubulins, and trithorax (show MLLT1 Antibodies) group proteins ALR-1, ALR-2 (show AKR1B1 Antibodies), HALR, and ASH2 (show ASCL2 Antibodies).

  5. The activation of DNA-PK in the absence of DNA ends by the coactivator TRBP (show TARBP2 Antibodies) suggests a novel mechanism of coactivator-stimulated DNA-PK phosphorylation in transcriptional regulation.

  6. ASC-2 is a physiologically important transcriptional coactivator of LXRs and demonstrate its pivotal role in the liver lipid metabolism

  7. ASC-2 appears to contain at least three distinct nuclear receptor interaction domains; also, Rb and ASC-2 have roles in androgen receptor (show AR Antibodies) transactivation

  8. ASC-2 has a role in inducing target gene transcription during granulocytic differentiation through binding to ATF2 (show ATF2 Antibodies)

  9. results suggest that ASC-2 is a novel coactivator for HSF1 (show HSF1 Antibodies) and heat shock stress may contribute to the strong active transcription complex through sequential recruitment of HSF1 (show HSF1 Antibodies) and ASC-2.

  10. ASC-2 is a bona fide coactivator of the xenobiotic nuclear receptor CAR and mediate the specific xenobiotic response by CAR in vivo.

Mouse (Murine) Nuclear Receptor Coactivator 6 (NCOA6) interaction partners

  1. These results indicate that PRIP is implicated in BMP-induced osteoblast differentiation by the negative regulation of Smad (show SMAD1 Antibodies) phosphorylation, through the methylation of inhibitory Smad6 (show SMAD6 Antibodies).

  2. The results indicate that PRIP negatively regulates UCP1 (show UCP1 Antibodies)-mediated thermogenesis in brown adipocytes.

  3. Two independent mouse models of NCOA6 dysfunction develop severe dilated cardiomyopathy with impaired mitochondrial function and reduced activity of peroxisome proliferator-activated receptor delta (show PPARD Antibodies).

  4. The NCOA6 controls E(2) sensitivity and uterine receptivity by regulating multiple E(2)-signaling components.

  5. ASC-2 negatively affects hepatic insulin (show INS Antibodies) sensitivity, at least in part, through induction of the insulin (show INS Antibodies) signalling inhibitors SOCS1 (show SOCS1 Antibodies) and SOCS3 (show SOCS3 Antibodies).

  6. PRIP is implicated in the negative regulation of bone formation

  7. diverse physiological function of NCOA6 may be mediated by multiple isoforms expressed in different tissues and localized in different subcellular compartments

  8. methylation of transporter promoters by MLL3 as part of activating signal cointegrator-2 -containing complex is essential for activation of bile salt export pump (show ABCB11 Antibodies)

  9. The apoptotic-like processes in the transgenic lens were both p53 (show TP53 Antibodies)-dependent and p53 (show TP53 Antibodies)-independent. Lens-specific deletion of Ncoa6 also resulted in disrupted lens fiber cell differentiation.

  10. These results suggest that AIB3 is required for PPARgamma (show PPARG Antibodies) function in placental development and for normal heart development.

NCOA6 Antigen Profile

Protein Summary

The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with NCOA6

  • nuclear receptor coactivator 6 (NCOA6) antibody
  • nuclear receptor coactivator 6 (Tsp_14219) antibody
  • nuclear receptor coactivator 6 (Tsp_13372) antibody
  • nuclear receptor coactivator 6 (ncoa6) antibody
  • Nuclear receptor coactivator 6 (ncoa6) antibody
  • nuclear receptor coactivator 6 (Ncoa6) antibody
  • Aib3 antibody
  • ASC-2 antibody
  • ASC2 antibody
  • gb:dq017635 antibody
  • mKIAA0181 antibody
  • ncoa6 antibody
  • Ncoa7 antibody
  • NRC antibody
  • PRIP antibody
  • RAP250 antibody
  • Trbp antibody
  • wu:fb25d11 antibody

Protein level used designations for NCOA6

nuclear receptor coactivator 6 , Nuclear receptor coactivator 6 , NRC RAP250 , PPAR-interacting protein , activating signal cointegrator 2 , activating signal cointegrator-2 , amplified in breast cancer protein 3 , amplified in breast cancer-3 protein , cancer-amplified transcriptional coactivator ASC-2 , nuclear receptor coactivator RAP250 , nuclear receptor-activating protein, 250 kDa , peroxisome proliferator-activated receptor interacting protein , peroxisome proliferator-activated receptor-interacting protein , thyroid hormone receptor binding protein , thyroid hormone receptor-binding protein , PPAR interacting protein PRIP , nuclear receptor-activating protein 250 , peroxisome proliferator-activated receptor interacting protein,PRIP

GENE ID SPECIES
419122 Gallus gallus
10908202 Trichinella spiralis
10910561 Trichinella spiralis
100144559 Danio rerio
100196047 Salmo salar
23054 Homo sapiens
56406 Mus musculus
116464 Rattus norvegicus
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