You are viewing an incomplete version of our website. Please click to reload the website as full version.

Nuclear Receptor Coactivator 6 (NCOA6) ELISA Kits

The protein encoded by NCOA6 is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. Additionally we are shipping NCOA6 Antibodies (10) and NCOA6 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human NCOA6 NCOA6 23054 Q14686
Anti-Mouse NCOA6 NCOA6 56406  
Anti-Rat NCOA6 NCOA6 116464  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

More ELISA Kits for NCOA6 Interaction Partners

Human Nuclear Receptor Coactivator 6 (NCOA6) interaction partners

  1. The retinoid x receptor does not interact with the NR box-1 of ASC-2, but functions as an allosteric activator of LXR binding to NR box-2 of ASC-2.

  2. diverse physiological function of NCOA6 may be mediated by multiple isoforms expressed in different tissues and localized in different subcellular compartments

  3. NCOA6 is responsible for the synergistic activation of CYP2C9 (show CYP2C9 ELISA Kits) by HNF4alpha (show HNF4A ELISA Kits) and pregnane X receptor (show NR1I2 ELISA Kits) and NCOA6 differentially regulates CYP2C9 (show CYP2C9 ELISA Kits) and CYP3A4 (show CYP3A4 ELISA Kits) gene expression though both the genes are regulated by the same nuclear receptors.

  4. we show that ASC-2 belongs to a steady-state complex of approximately 2 MDa (ASC-2 complex [ASCOM]) in HeLa nuclei. ASCOM contains retinoblastoma-binding protein RBQ-3, alpha/beta-tubulins, and trithorax group proteins ALR-1, ALR-2, HALR, and ASH2.

  5. The activation of DNA-PK in the absence of DNA ends by the coactivator TRBP suggests a novel mechanism of coactivator-stimulated DNA-PK phosphorylation in transcriptional regulation.

  6. ASC-2 is a physiologically important transcriptional coactivator of LXRs and demonstrate its pivotal role in the liver lipid metabolism

  7. ASC-2 appears to contain at least three distinct nuclear receptor interaction domains; also, Rb and ASC-2 have roles in androgen receptor (show AR ELISA Kits) transactivation

  8. ASC-2 has a role in inducing target gene transcription during granulocytic differentiation through binding to ATF2 (show ATF2 ELISA Kits)

  9. results suggest that ASC-2 is a novel coactivator for HSF1 and heat shock stress may contribute to the strong active transcription complex through sequential recruitment of HSF1 and ASC-2.

  10. ASC-2 is a bona fide coactivator of the xenobiotic nuclear receptor CAR and mediate the specific xenobiotic response by CAR in vivo.

Mouse (Murine) Nuclear Receptor Coactivator 6 (NCOA6) interaction partners

  1. These results indicate that PRIP is implicated in BMP-induced osteoblast differentiation by the negative regulation of Smad (show SMAD1 ELISA Kits) phosphorylation, through the methylation of inhibitory Smad6 (show SMAD6 ELISA Kits).

  2. The results indicate that PRIP negatively regulates UCP1 (show UCP1 ELISA Kits)-mediated thermogenesis in brown adipocytes.

  3. Two independent mouse models of NCOA6 dysfunction develop severe dilated cardiomyopathy with impaired mitochondrial function and reduced activity of peroxisome proliferator-activated receptor delta (show PPARD ELISA Kits).

  4. The NCOA6 controls E(2) sensitivity and uterine receptivity by regulating multiple E(2)-signaling components.

  5. ASC-2 negatively affects hepatic insulin (show INS ELISA Kits) sensitivity, at least in part, through induction of the insulin (show INS ELISA Kits) signalling inhibitors SOCS1 (show SOCS1 ELISA Kits) and SOCS3 (show SOCS3 ELISA Kits).

  6. PRIP is implicated in the negative regulation of bone formation

  7. diverse physiological function of NCOA6 may be mediated by multiple isoforms expressed in different tissues and localized in different subcellular compartments

  8. methylation of transporter promoters by MLL3 as part of activating signal cointegrator-2 -containing complex is essential for activation of bile salt export pump (show ABCB11 ELISA Kits)

  9. The apoptotic-like processes in the transgenic lens were both p53 (show TP53 ELISA Kits)-dependent and p53 (show TP53 ELISA Kits)-independent. Lens-specific deletion of Ncoa6 also resulted in disrupted lens fiber cell differentiation.

  10. These results suggest that AIB3 is required for PPARgamma (show PPARG ELISA Kits) function in placental development and for normal heart development.

NCOA6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with NCOA6

  • nuclear receptor coactivator 6 (NCOA6) antibody
  • nuclear receptor coactivator 6 (Tsp_14219) antibody
  • nuclear receptor coactivator 6 (Tsp_13372) antibody
  • nuclear receptor coactivator 6 (ncoa6) antibody
  • Nuclear receptor coactivator 6 (ncoa6) antibody
  • nuclear receptor coactivator 6 (Ncoa6) antibody
  • Aib3 antibody
  • ASC-2 antibody
  • ASC2 antibody
  • gb:dq017635 antibody
  • mKIAA0181 antibody
  • ncoa6 antibody
  • Ncoa7 antibody
  • NRC antibody
  • PRIP antibody
  • RAP250 antibody
  • Trbp antibody
  • wu:fb25d11 antibody

Protein level used designations for NCOA6

nuclear receptor coactivator 6 , Nuclear receptor coactivator 6 , NRC RAP250 , PPAR-interacting protein , activating signal cointegrator 2 , activating signal cointegrator-2 , amplified in breast cancer protein 3 , amplified in breast cancer-3 protein , cancer-amplified transcriptional coactivator ASC-2 , nuclear receptor coactivator RAP250 , nuclear receptor-activating protein, 250 kDa , peroxisome proliferator-activated receptor interacting protein , peroxisome proliferator-activated receptor-interacting protein , thyroid hormone receptor binding protein , thyroid hormone receptor-binding protein , PPAR interacting protein PRIP , nuclear receptor-activating protein 250 , peroxisome proliferator-activated receptor interacting protein,PRIP

GENE ID SPECIES
419122 Gallus gallus
10908202 Trichinella spiralis
10910561 Trichinella spiralis
100144559 Danio rerio
100196047 Salmo salar
23054 Homo sapiens
56406 Mus musculus
116464 Rattus norvegicus
Did you look for something else?