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Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. Additionally we are shipping Nucleolar Complex Associated 2 Homolog (S. Cerevisiae) Proteins (3) and many more products for this protein.
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Human Polyclonal NOC2L Primary Antibody for ELISA, WB - ABIN1451409
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
A transcriptional repressor NIR functions in the rRNA biogenesis of both the 40S and 60S subunits.
Aurora B (show AURKB Antibodies) interacts with NIR-p53 (show TP53 Antibodies), leading to p53 (show TP53 Antibodies) phosphorylation in its DNA-binding domain and subsequent functional suppression.
Upon recruitment by p53 (show TP53 Antibodies), NIR represses transcription of both p53 (show TP53 Antibodies)-dependent reporters and endogenous target genes
results show that NIR cooperate with p53 (show TP53 Antibodies) to impose checkpoint for the generation of mature B and T lymphocytes.
Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005
, novel INHAT (inhibitor of histone acetyltransferase) repressor
, novel INHAT repressor
, nucleolar complex protein 2 homolog
, protein NOC2 homolog