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Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and\\/or MA3 domains, such as NOM1, function in protein translation. Additionally we are shipping and many more products for this protein.
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Human Polyclonal NOM1 Primary Antibody for IHC, ELISA - ABIN1535129
Simmons, Ruis, Kapoor, Hudacek, Conklin: Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. in Gene 2005
Show all 2 references for ABIN1535129
demonstrate direct physical interactions between yeast Sgd1p and Fal1p, and between their human orthologs (NOM1 and eIF4AIII (show EIF4A3 Antibodies)) in vitro and in vivo, identifying human NOM1 as a missing eIF4G (show EIF4G1 Antibodies)-like interacting partner of eIF4AIII (show EIF4A3 Antibodies)
Data demonstrate that NOM1 can target PP1 (show PPA1 Antibodies) to the nucleolus and show NOM1 nucleolar localization sequence are required for this targeting activity and conclude that NOM1 is a PP1 (show PPA1 Antibodies) nucleolar targeting subunit, the first identified in eukaryotic cells.
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1\; MIM 602641) (Simmons et al., 2005
, nucleolar MIF4G domain-containing protein 1