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Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and\\/or MA3 domains, such as NOM1, function in protein translation. Additionally we are shipping Nucleolar Protein with MIF4G Domain 1 Antibodies (9) and and many more products for this protein.
demonstrate direct physical interactions between yeast Sgd1p and Fal1p, and between their human orthologs (NOM1 and eIF4AIII (show EIF4A3 ELISA Kits)) in vitro and in vivo, identifying human NOM1 as a missing eIF4G (show EIF4G1 ELISA Kits)-like interacting partner of eIF4AIII (show EIF4A3 ELISA Kits)
Data demonstrate that NOM1 can target PP1 (show PPA1 ELISA Kits) to the nucleolus and show NOM1 nucleolar localization sequence are required for this targeting activity and conclude that NOM1 is a PP1 (show PPA1 ELISA Kits) nucleolar targeting subunit, the first identified in eukaryotic cells.
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1\; MIM 602641) (Simmons et al., 2005
, nucleolar MIF4G domain-containing protein 1