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Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. Additionally we are shipping Nucleolin Antibodies (140) and Nucleolin Kits (5) and many more products for this protein.
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Human Nucleolin Protein expressed in Wheat germ - ABIN1312119
Tsoi, Lau, Tsang, Lau, Chan: CAG expansion induces nucleolar stress in polyglutamine diseases. in Proceedings of the National Academy of Sciences of the United States of America 2012
Show all 3 references for ABIN1312119
Suggest that during heart disease nucleolin is reactivated to mobilize conserved aspects of chromatin remodeling and gene expression.
Disruption of the AtNUC-L1 gene induces loss of symmetrical DNA methylation (show HELLS Proteins) without affecting histone epigenetic marks at rRNA genes.
PARL1 protein has roles similar to those of the yeast nucleolin in nuclear signal recognition, ribosomal processing, and ribosomal subunit accumulation.
In U87 glioma cells, C23 plays a crucial role in activation of SDF-1 (show CXCL12 Proteins)-induced ERK (show EPHB2 Proteins) and PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathways via interacting with CXCR4 (show CXCR4 Proteins). C23 interacted with CXCR4 (show CXCR4 Proteins) once U87 was exposed to SDF-1 (show CXCL12 Proteins) treatment.
HAUSP (show USP7 Proteins)-nucleolin interaction is regulated by p53 (show TP53 Proteins)-Mdm2 (show MDM2 Proteins) complex in response to DNA damage.
These results suggested a clear link between nucleolin expression (including cell membrane nucleolin) and the stem cell-like phenotype in breast cancer, namely in the triple negative molecular subtype.
Identification of NCL (show CLN5 Proteins) as a prominent host factor capable of binding with high affinity to the G4 structures present in the LTR promoter of HIV-1.
NCL (show CLN5 Proteins) overexpression is involved in liver carcinogenesis.
NCL (show CLN5 Proteins) is implicated in the initiation and transduction of EGFR (show EGFR Proteins) and CXCR4 (show CXCR4 Proteins) signaling in the esophageal squamous cell carcinomas.NCL is expressed in the esophageal squamous cell carcinoma tissues with metastasis in the cell membrane, cytoplasm and nucleus.
Data suggest that NCL (nucleolin) is re-localized during lytic KSHV (Kaposi sarcoma-associated herpesvirus) infection and protects IL6 (interleukin-6 (show IL6 Proteins)) mRNA from SOX (show PIPOX Proteins) (KSHV cytoplasmic mRNA-specific endonuclease) degradation in cytoplasm.
The involvement of cell surface nucleolin in the initiation of CCR6 (show CCR6 Proteins) signaling in human hepatocellular carcinoma.Expression of nucleolin and CCR6 (show CCR6 Proteins) correlates with overall survival in hepatocellular carcinoma patients.
C23 protein meditates bone morphogenetic protein-2 (show BMP2 Proteins)-mediated epithelial-to-mesenchymal transition via up-regulation of Erk1 (show MAPK3 Proteins)/Erk2 (show MAPK1 Proteins) and Akt (show AKT1 Proteins) in gastric cancer.Correlations between C23, BMPRII (show BMPR2 Proteins) expression and prognosis of gastric cancer patients.
study dissects nucleolin-mediated activation of surface AC133 and its cognate gene CD133, via specific interaction of nucleolin with the tissue-dependent CD133 promoter P1
Nucleolin Acts as a Scavenger Receptor for Acetylated Low-Density Lipoprotein on Macrophages
Nucleolin is a receptor for maleylated-bovine serum albumin (show ALB Proteins) on macrophages
Lrrc34, a novel nucleolar protein (show MCRS1 Proteins), interacts with npm1 (show GJA1 Proteins) and ncl and has an impact on pluripotent stem cells
results indicate that nucleolin is a receptor that allows macrophages to recognize toxic Advanced glycosylation end-products.
results for the first time demonstrate that nucleolin-SUMO at K294R plays a critical role in its nucleus sequestration and gadd45alpha (show GADD45A Proteins) mRNA binding activity.
Nucleolin-FGF1 interaction is critical for the intranuclear phosphorylation of FGF1 by PKCdelta and thereby the regulation of nuclear export of FGF1.
ANKRD1 (show ANKRD1 Proteins), in association with factors such as nucleolin, represses MMP13 (show MMP13 Proteins) transcription. Ankrd1 (show ANKRD1 Proteins) deletion additionally relieved MMP10 (show MMP10 Proteins) transcriptional repression
Nucleolin is involved in the regulation of ischemia reperfusion-induced cardiac injury and dysfunction via the regulation of Hsp32 (show HMOX1 Proteins).
Data indicate that increased expression of interleukin-9 receptor (Il9R (show IL9R Proteins)) is associated with an increased binding of nucleolin.
Data show that si-RNA induced down-regulation of FUT1 (show FUT1 Proteins) and FUT2 (show FUT2 Proteins) reduced expression of fucosylated nucleolin glycoforms and their exposure at the cell surface.
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
, eukaryotic translation initiation factor 3 subunit A
, Eukaryotic translation initiation factor 3 subunit 10
, nucleolin-like protein
, protein C23