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Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) ELISA Kits

NOD2 is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). Additionally we are shipping NOD2 Antibodies (110) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NOD2 64127 Q9HC29
NOD2 257632  
Anti-Rat NOD2 NOD2 291912  
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Top NOD2 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 6.25 pg/ml 25-1600 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 3.9 pg/ml 15.6-1000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for NOD2 Interaction Partners

Human Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Significant associations were found between Crohn's disease (CD) and minor NOD2 variants, as well as TLR4 (show TLR4 ELISA Kits) 299Gly, TNF-alpha (show TNF ELISA Kits) G-308A, IL-6 (show IL6 ELISA Kits) G-174C and IL-1RN (show IL1RN ELISA Kits) VNTR A2 variants, while ulcerative colitis (UC) was associated only with IL-1RN (show IL1RN ELISA Kits) VNTR A2 variants.

  2. CaSR (show CASR ELISA Kits)-induced constitutive macropinocytosis facilitates the sentinel function of macrophages, promoting the efficient delivery of ligands to cytosolic pattern-recognition receptors.

  3. The INCA (show CARD17 ELISA Kits) trial (impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver cirrhosis and ascites): precision medicine for patients with liver cirrhosis and ascites

  4. This is the first description of gonosomal NOD2 mosaicism as the cause of intrafamilial recurrence of Blau syndrome.

  5. the rs2066847 variant of the NOD2/CARD15 gene is not associated with lung cancer risk in the Turkish population

  6. data describe donor NOD2 SNP13 as a significant risk factor for the development of septic shock after allogeneic stem cell transplantation

  7. NOD1 (show NOD1 ELISA Kits) and NOD2, two members of the NOD-like receptor family of pattern recognition receptors, are important mediators of ER-stress-induced inflammation in mouse and human cells

  8. Blau syndrome has been strongly associated with mutations in the NOD2 gene. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201507-1344LE#.VrgfNNL2byA

  9. None of the NOD2/CARD15 variants was statistically associated to CRC (show CALR ELISA Kits) susceptibility in our Malaysian population.

  10. data demonstrate that in Crohn's disease patients the IVS4+10 A>C NOD2 variant is strongly associated with the development of perianal fistulas

Mouse (Murine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. CD44 (show CD44 ELISA Kits), NOD2, and Fas (show FAS ELISA Kits) have distinct functions in regulating changes in trabecular and cortical bone indices during unloading.

  2. The results indicate that Nod1 (show NOD1 ELISA Kits) cooperates with Nod2 or TLRs to produce cytokines in macrophages in response to M. tuberculosis infection.

  3. Myocardial ischemia reperfusion injury markedly up-regulated NOD2 expression in heart tissue.

  4. A novel crosstalk between TLR4 (show TLR4 ELISA Kits)- and NOD2-mediated signaling in the regulation of intestinal inflammation

  5. Nod2-/- alveolar macrophages and blood neutrophils displayed a reduced capacity to internalize pneumococci in vitro.

  6. NOD1 (show NOD1 ELISA Kits) and NOD2, play a collaborative role in T cell activation by alloantigen and that their blockade in vitro can inhibit T cell responses.

  7. NOD2 and its downstream adaptor protein IPS-1 (show ISYNA1 ELISA Kits) have been found to be essential for LTB4 (show PTGR1 ELISA Kits)-mediated effects against IAV infection.

  8. helminth infection protects mice deficient in the Crohn's disease susceptibility gene Nod2 from intestinal abnormalities by inhibiting colonization by an inflammatory Bacteroides species.

  9. NOD1 (show NOD1 ELISA Kits) and NOD2, two members of the NOD-like receptor family of pattern recognition receptors, are important mediators of ER-stress-induced inflammation in mouse and human cells

  10. Macrophages from nod2 mutant R314Q mice and from patients from Blau syndrome showed reduced cytokine production and intracellular signaling of pathways normally activated by muramyl dipeptide

Cow (Bovine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows.

  2. Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields.

  3. Genetic variation and putative regulatory regions in bovine CARD15.

  4. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.

NOD2 Antigen Profile

Antigen Summary

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Gene names and symbols associated with NOD2

  • caspase recruitment domain 15 protein (TTHERM_01951320) antibody
  • nucleotide-binding oligomerization domain containing 2 (NOD2) antibody
  • nucleotide-binding oligomerization domain containing 2 (Nod2) antibody
  • ACUG antibody
  • BLAU antibody
  • Card15 antibody
  • CD antibody
  • CLR16.3 antibody
  • F830032C23Rik antibody
  • IBD1 antibody
  • Nlrc2 antibody
  • NOD2B antibody
  • PSORAS1 antibody

Protein level used designations for NOD2

caspase recruitment domain 15 protein , NLR family, CARD domain containing 2 , NOD-like receptor C2 , caspase recruitment domain family, member 15 , caspase recruitment domain protein 15 , caspase recruitment domain-containing protein 15 , inflammatory bowel disease protein 1 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2 , nucleotide-binding oligomerization domain-containing protein 2

GENE ID SPECIES
7828465 Tetrahymena thermophila
64127 Homo sapiens
257632 Mus musculus
291912 Rattus norvegicus
444867 Bos taurus
454083 Pan troglodytes
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