You are viewing an incomplete version of our website. Please click to reload the website as full version.

Numb Homolog Proteins (NUMB)

The protein encoded by NUMB plays a role in the determination of cell fates during development. Additionally we are shipping NUMB Antibodies (154) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NUMB 18222 Q9QZS3
NUMB 8650 P49757
NUMB 29419  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top NUMB Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,890.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details
HOST_Sf-9 Cells Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$460.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

NUMB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human , , ,
, ,
Rat (Rattus)

More Proteins for Numb Homolog (NUMB) Interaction Partners

Mouse (Murine) Numb Homolog (NUMB) interaction partners

  1. Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4 (show TLR4 Proteins).

  2. Loss of Numb induces a p53 (show TP53 Proteins)-dependent senescence following skeletal muscle injury.

  3. Numb is a regulator for constitutive expression and dynamic transport of mGlu1 (show GRM1 Proteins).

  4. we observed a glial reaction and an activity-dependent modification of Shh (show SHH Proteins), Noggin (show NOG Proteins), and Numb proteins. we found that Shh (show SHH Proteins) and Noggin (show NOG Proteins) could affect motor performance and that these proteins could be associated with both TDP-43 (show TARDBP Proteins) and Numb

  5. Numb ensures the asymmetric outcome of self-renewing divisions by partitioning into the progeny that retains the stem cell identity, where it sustains high p53 (show TP53 Proteins) activity.

  6. findings demonstrate that Nb and Nbl are intrinsic factors crucial for the renewal of CPCs in the PA2 and that the PA2 serves as a microenvironment for their expansion

  7. Numb/Numbl (show NUMBL Proteins) control VEGF receptor (show FLT1 Proteins) endocytosis, signaling, and recycling in endothelial cells, which promotes the angiogenic growth of blood vessels.

  8. Nuclear localization of Numb in early thymocyte precursors favors p53 (show TP53 Proteins) nuclear stabilization, whereas pre-T-cell receptor (show PTCRA Proteins)-dependent Numb nuclear exclusion promotes the p53 (show TP53 Proteins) downmodulation essential for further differentiation.

  9. Numb promotes the trafficking of Cnga1 (show CNGA1 Proteins) in rod photoreceptor cilia.

  10. The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1 (show NPC1L1 Proteins).

Human Numb Homolog (NUMB) interaction partners

  1. Dominant negative NUMB expression confers a high proliferative phenotype to chronic myeloid leukemia (show BCL11A Proteins) cells.

  2. Alternative splicing of APP (show APP Proteins), VEGFA (show VEGFA Proteins) and NUMB may play an important role in pathogenesis of pancreatic ductal adenocarcinoma.

  3. Notch1 (show NOTCH1 Proteins)/Numb/Snail (show SNAI1 Proteins) signal pathway plays an important role in the pathogenesis of adenomyosis.

  4. Numb polymorphisms are associated with coronary artery disease among Han Chinese and Uighur Chinese in Xinjiang, China.

  5. Methylation of the Numb promoter contributed to hepatocarcinogenesis.

  6. results indicated that both rs2108552 and rs17781919 in the Numb gene were associated with total cholesterol level and density lipoprotein-cholesterol level in Chinese subjects.

  7. Report alternative splicing of NUMB in colorectal cancer.

  8. NANOG-NUMB-p53 signaling axis is an important regulatory pathway for tumor-initiating cells events in TIC self-renewal and liver tumorigenesis

  9. Alternative splicing of Numb may provide a useful prognostic biomarker in HCC (show FAM126A Proteins) and is pharmacologically tractable

  10. The ability of RBM10v1 to regulate alternative splicing depends, at least in part, on a structural alteration within the second RNA recognition motif domain, and correlates with preferential expression of the NUMB exon 11 inclusion variant.

NUMB Protein Profile

Protein Summary

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Numb Homolog Proteins (NUMB)

  • numb gene homolog (Drosophila) (Numb)
  • numb homolog (Drosophila) (NUMB)
  • numb homolog (Drosophila) (Numb)
  • C14orf41 protein
  • c14_5527 protein
  • Nb protein
  • S171 protein

Protein level used designations for Numb Homolog Proteins (NUMB)

protein numb homolog , h-Numb , numb gene homolog

GENE ID SPECIES
18222 Mus musculus
480381 Canis lupus familiaris
395639 Gallus gallus
8650 Homo sapiens
29419 Rattus norvegicus
512187 Bos taurus
100522019 Sus scrofa
Selected quality suppliers for NUMB Proteins (NUMB)
Did you look for something else?