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NUMBL Proteins

(Numb Homolog (Drosophila)-Like (NUMBL))
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
NUMBL Protein (AA 1-609) (Strep Tag) NUMBL Protein (AA 1-609) (Strep Tag) NUMBL Protein (AA 1-609) (Strep Tag) (ABIN3094283)

Crystallography grade NUMBL Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

NUMBL Protein (AA 1-604) (Strep Tag) NUMBL Protein (AA 1-604) (Strep Tag) NUMBL Protein (AA 1-604) (Strep Tag) (ABIN3131350)

Crystallography grade NUMBL Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

NUMBL Protein (Myc-DYKDDDDK Tag) NUMBL Protein (Myc-DYKDDDDK Tag) NUMBL Protein (Myc-DYKDDDDK Tag) (ABIN2727806)

NUMBL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

NUMBL Proteins by Grade

Find NUMBL Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NUMBL Proteins by Origin

Find NUMBL Proteins for a variety of species such as anti-Human NUMBL, anti-Mouse NUMBL, anti-Rat NUMBL. The species listed below are among those available. Click on a link to go to the corresponding products.

NUMBL Proteins by Source

Here you will find NUMBL Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

NUMBL Proteins by Protein Type

Here you can find NUMBL Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

NUMBL Proteins by Application

Find NUMBL Proteins validated for a specific application such as ELISA, SDS, WB, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular NUMBL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094283
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3131350
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727806
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475268
Quantity 1 mg
Datasheet Datasheet

Aliases for NUMBL Proteins

NUMB like, endocytic adaptor protein (NUMBL) Proteins
numb homolog-like L homeolog (numbl.L) Proteins
NUMB-like, endocytic adaptor protein (Numbl) Proteins
numb-like (Numbl) Proteins
cag3a Proteins
CAG3A Proteins
ctg3a Proteins
CTG3a Proteins
nbl Proteins
NBL Proteins
numb Proteins
numb-r Proteins
NUMB-R Proteins
numblike Proteins
NUMBLIKE Proteins
numbr Proteins
NUMBR Proteins
tnrc23 Proteins
TNRC23 Proteins
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