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ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) ELISA Kits

The protein encoded by ORAI1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Additionally we are shipping ORAI1 Antibodies (123) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ORAI1 84876 Q96D31
ORAI1 109305 Q8BWG9
ORAI1 304496 Q5M848
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Top ORAI1 ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Human
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$875.60
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Rat
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$875.60
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Chicken
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$1,095.60
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More ELISA Kits for ORAI1 Interaction Partners

Zebrafish ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. The findings identify ORAI1 as an important regulator of cardiac and skeletal muscle function and provide evidence linking ORAI1-mediated calcium signaling to sarcomere integrity and cardiomyocyte function.

Xenopus laevis ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. The Orai1 actively recycles between an endosomal compartment and the cell membrane through a Rho-dependent endocytic pathway.

Silk Worm ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. STIM1 (show STIM1 ELISA Kits) and Orai1 are essential components of the signal transduction cascade that regulates sex pheromone production.

Human ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. Coupling of the endoplasmic reticulum (ER) Ca(2 (show CA2 ELISA Kits)+)sensor, stromal interaction molecule 1 (STIM1 (show STIM1 ELISA Kits)), to the Ca(2 (show CA2 ELISA Kits)+)-selective channel, Orai1, is regulated by these elements and depends on membrane organization, both at the plasma membrane and at the ER

  2. Decreased Orai1 expression was observed in human term-pregnant laboring myometrium compared with non-pregnant myometrium.

  3. identified a Ca(2 (show CA2 ELISA Kits)+)-accumulating region (CAR) in the extracellular opening of Orai1, which explains how concentrating Ca(2 (show CA2 ELISA Kits)+) at the mouth of Orai1 facilitates channel permeation and contributes to selectivity.

  4. These data suggest that cell type-specific glycosylation influences the interaction of Orai1 with specific lectins, such as Siglecs, which then attenuates SOCE. In summary, the glycosylation state of Orai1 influences SOCE-mediated Ca(2 (show CA2 ELISA Kits)+) signaling and, thus, may contribute to pathophysiological Ca(2 (show CA2 ELISA Kits)+) signaling observed in immune disease and cancer

  5. results identified the ORAI-NOX2 (show CYBB ELISA Kits) feedback loop as a determinant of monocyte immune responses.

  6. Orai1 senses the amount of cholesterol in the plasma membrane and the interaction of Orai1 with cholesterol inhibits its activity, thereby limiting store-operated Ca(2 (show CA2 ELISA Kits)+) entry

  7. The crystal structure of Ca(2 (show CA2 ELISA Kits)+)-CaM (show CALM1 ELISA Kits) bound to an Orai1 N-terminal peptide.

  8. STIM11-469 and Orai1 W76A mutants do not reduce channel open probability.

  9. T Cell Receptor-induced Nuclear Factor kappaB (NF-kappaB (show NFKB1 ELISA Kits)) Signaling and Transcriptional Activation Are Regulated by STIM1 (show STIM1 ELISA Kits)- and Orai1-mediated Calcium Entry.

  10. We demonstrate that the Orai1/STIM1 (show STIM1 ELISA Kits) channel is regulated by changes of both intracellular and extracellular pH.

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. In Dicer (show DICER1 ELISA Kits)-deficient mice Orai1 (show TMEM132A ELISA Kits) was down-regulated at mRNA and protein level in CD4 (show CD4 ELISA Kits)+ T cells.

  2. results identified the ORAI-NOX2 (show CYBB ELISA Kits) feedback loop as a determinant of monocyte immune responses.

  3. Orai1 (show TMEM132A ELISA Kits)-dependent Ca(2 (show CA2 ELISA Kits)+) entry promotes atherogenesis possibly by promoting foam cell formation and vascular inflammation, rendering orai1 (show TMEM132A ELISA Kits) Ca(2 (show CA2 ELISA Kits)+) channel a potential therapeutic target against atherosclerosis.

  4. alternative translation initiation of the Orai1 (show TMEM132A ELISA Kits) message produces at least three types of Ca(2 (show CA2 ELISA Kits)+) channels with distinct signaling and regulatory properties.

  5. Orai1 (show TMEM132A ELISA Kits) and STIM1 (show STIM1 ELISA Kits) have roles in inhibiting matrix protein expression

  6. SOCE blockers or ablation of STIM1 (show STIM1 ELISA Kits), STIM2 (show Stim2 ELISA Kits), or Orai1 (show TMEM132A ELISA Kits) severely impaired nucleotide-induced migration and phagocytosis in microglia.

  7. Our data establish Orai1 (show TMEM132A ELISA Kits) as key signal mediator of C5aR (show C5AR1 ELISA Kits) activation, contributing to inflammation

  8. Orai1 (show TMEM132A ELISA Kits) store-operated calcium channels have an essential role in lactation

  9. TRPC6 (show TRPC6 ELISA Kits) activity can occur independently of the physical interaction with Orai1 (show TMEM132A ELISA Kits)

  10. Data show that increased activity of STIM1 (show STIM1 ELISA Kits)-Orai1 (show TMEM132A ELISA Kits) complex inducing enhanced Ca(2 (show CA2 ELISA Kits)+) influx is a disease determinant in muscular dystrophy.

ORAI1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).

Gene names and symbols associated with ORAI1

  • ORAI calcium release-activated calcium modulator 1b (orai1b) antibody
  • ORAI calcium release-activated calcium modulator 1 (orai1) antibody
  • ORAI calcium release-activated calcium modulator 1 (ORAI1) antibody
  • ORAI calcium release-activated calcium modulator 1 (Orai1) antibody
  • ORAI calcium release-activated calcium modulator 1 (LOC100218031) antibody
  • ORAI calcium release-activated calcium modulator 2 (orai2) antibody
  • CRACM1 antibody
  • D730049H07Rik antibody
  • im:7146264 antibody
  • LOC100218031 antibody
  • orai-1 antibody
  • ORAI1 antibody
  • orai2 antibody
  • ORAT1 antibody
  • RGD1311873 antibody
  • Tmem142a antibody
  • tmem142b antibody
  • zgc:109721 antibody

Protein level used designations for ORAI1

ORAI calcium release-activated calcium modulator 1 , calcium release-activated calcium channel protein 1 , protein orai-1 , transmembrane protein 142A , protein orai-2 , transmembrane protein 142B , calcium release-activated calcium modulator 1 , calcium release-activated calcium channel 1

GENE ID SPECIES
402892 Danio rerio
403390 Xenopus laevis
473293 Pan troglodytes
700190 Macaca mulatta
100125061 Xenopus (Silurana) tropicalis
100188931 Bombyx mori
100218031 Taeniopygia guttata
84876 Homo sapiens
486261 Canis lupus familiaris
100154923 Sus scrofa
517688 Bos taurus
109305 Mus musculus
304496 Rattus norvegicus
416845 Gallus gallus
734537 Xenopus laevis
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