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ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) ELISA Kits

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity). Additionally we are shipping ORAI2 Antibodies (32) and ORAI2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat ORAI2 ORAI2 304592  
Anti-Mouse ORAI2 ORAI2 100043803  
Anti-Human ORAI2 ORAI2 80228 Q96SN7
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More ELISA Kits for ORAI2 Interaction Partners

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) interaction partners

  1. The data from this study indicate that upregulation of STIM2 (show Stim2 ELISA Kits) and Orai2 is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.

  2. Data indicate that the Ca(2 (show CA2 ELISA Kits)+) release-activated Ca(2 (show CA2 ELISA Kits)+) channels (CRAC) blocker GSK-7975A inhibited store-operated Ca(2 (show CA2 ELISA Kits)+) entry in a concentration-dependent manner.

Human ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) interaction partners

  1. Orai1 (show ORAI1 ELISA Kits), Orai2 and STIM1 (show STIM1 ELISA Kits) form functional Ca(2 (show CA2 ELISA Kits)+) release-activated Ca(2 (show CA2 ELISA Kits)+) channels in OUMS-27 cells (chondrocytes) and that these complexes are responsible for sustained Ca(2 (show CA2 ELISA Kits)+) entry in response to agonist stimulation.

  2. The higher amplitude of store-operated Ca2 (show CA2 ELISA Kits)+ entry was associated to the over-expression for Stim2 (show Stim2 ELISA Kits), Orai2-3, and TRPC1 (show TRPC1 ELISA Kits) while Stim2 (show Stim2 ELISA Kits) levels remained constant and Stim1 (show STIM1 ELISA Kits), Orai1 (show ORAI1 ELISA Kits), Orai3 (show ORAI3 ELISA Kits), TRPC1 (show TRPC1 ELISA Kits) and TRPC4 (show TRPC4 ELISA Kits) proteins were over-expressed in primary myelofibrosis.

  3. Orai1 (show ORAI1 ELISA Kits) but not Orai2 plays a major role in the influx of extracellular Ca2 (show CA2 ELISA Kits)+ into and mediator release from HLMCs following their activation

  4. Orai1 (show ORAI1 ELISA Kits) and Orai2 operate in a STIM-dependent manner, Orai3 (show ORAI3 ELISA Kits) does not interact with STIM isoforms upon calcium store depletion in platelets.

  5. With these data we show a new Ca(2)(+) entry pathway linked to the Ca(2)(+)/inositolphosphate second-messenger system in RPE cells which help to further understand regulatory pathways of agonists.

  6. Results suggest that Orai1 (show ORAI1 ELISA Kits), -2, and -3 channels are similarly inhibited by extracellular calcium, indicating similar affinities for Ca(2 (show CA2 ELISA Kits)+) within the selectivity filter.

  7. The effects of 2-aminoethoxydiphenyl borate on orai1 (show ORAI1 ELISA Kits), orai2, orai3 (show ORAI3 ELISA Kits) metabolism in HEK293 cells with and without STIM1 (show STIM1 ELISA Kits) are reported.

  8. analysis of activation of Orai1 (show ORAI1 ELISA Kits)-3 channels by a STIM1 (show STIM1 ELISA Kits) coiled-coil mutant

  9. Data show that the fast Ca(2 (show CA2 ELISA Kits)+)-dependent inactivation is mediated by three conserved glutamates in the C termini (CT) of Orai2 and Orai3 (show ORAI3 ELISA Kits), which show prominent fast Ca(2 (show CA2 ELISA Kits)+)-dependent inactivation compared with Orai1 (show ORAI1 ELISA Kits).

Cow (Bovine) ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) interaction partners

  1. Orai2 is specifically up-regulated during the G2/M phase, negatively modulates the store-operated Ca(2 (show CA2 ELISA Kits)+) entry activity, and may contribute to the regulation of cell cycle progression in brain capillary endothelial cells.

ORAI2 Antigen Profile

Antigen Summary

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity).

Gene names and symbols associated with ORAI2

  • ORAI calcium release-activated calcium modulator 2 (Orai2) antibody
  • ORAI calcium release-activated calcium modulator 2 (ORAI2) antibody
  • predicted gene 4659 (Gm4659) antibody
  • ORAI calcium release-activated calcium modulator 2 (LOC100230993) antibody
  • ORAI calcium release-activated calcium modulator 2 (LOC100349347) antibody
  • ORAI calcium release-activated calcium modulator 2 (LOC100358487) antibody
  • ORAI calcium release-activated calcium modulator 2 (LOC100359269) antibody
  • ORAI calcium release-activated calcium modulator 2 (orai2) antibody
  • A730041O15Rik antibody
  • C7orf19 antibody
  • CBCIP2 antibody
  • LOC100230993 antibody
  • MEM142B antibody
  • Orai2 antibody
  • RGD1310213 antibody
  • Tmem142b antibody

Protein level used designations for ORAI2

CAP-binding protein complex interacting protein 2 , calcium release-activated calcium modulator 2 protein , ORAI calcium release-activated calcium modulator 2 , calcium release-activated calcium channel 2 , CAP-binding protein complex-interacting protein 2 , H_NH0514P08.8 , protein orai-2 , putative protein ORAI2-2 , transmembrane protein 142B

GENE ID SPECIES
304592 Rattus norvegicus
463930 Pan troglodytes
100043803 Mus musculus
100230993 Taeniopygia guttata
100349347 Oryctolagus cuniculus
100358487 Oryctolagus cuniculus
100359269 Oryctolagus cuniculus
100380109 Xenopus (Silurana) tropicalis
80228 Homo sapiens
269717 Mus musculus
608106 Canis lupus familiaris
511233 Bos taurus
417509 Gallus gallus
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