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ORM1-Like 3 (S. Cerevisiae) Proteins (ORMDL3)

Negative regulator of sphingolipid synthesis. Additionally we are shipping ORMDL3 Antibodies (25) and ORMDL3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ORMDL3 94103 Q8N138
ORMDL3 66612 Q9CPZ6
Rat ORMDL3 ORMDL3 360618 Q6QI25
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Top ORMDL3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

ORMDL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for ORM1-Like 3 (S. Cerevisiae) (ORMDL3) Interaction Partners

Human ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. The TT homozygote and the T allele of rs7216389 in ORMDL3 increased bronchiolitis risk. The rs7216389 polymorphism may be a predictor for identifying infants with predisposition to virus-induced wheezing to persistent asthma.

  2. Two single nucleotide polymorphisms regulating ORMDL3 expression (rs7216389 and rs9303277) significantly associated with atherosclerosis risk and the evidence of increased ORMDL3 expression in AS cases compared to controls.

  3. The SNP (rs7216389) of ORMDL3 does not influence the expression of OPN (show SPP1 Proteins) and TGF-beta1 (show TGFB1 Proteins), suggesting that it may not be associated with airway remodeling.

  4. ORMDL3 variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.

  5. The meta-analysis indicates that ORMDL3 rs7216389 may contribute to increasing susceptibility to asthma. (Meta-analysis)

  6. the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism

  7. results show that Cbl-b suppresses human ORMDL3 expression through STAT6 (show STAT6 Proteins)

  8. Pro-inflammatory gene ORMDL3 SNP rs12603332 may be associated with high LysoPC and apoB (show APOB Proteins) levels, which leads to the occurrence of childhood asthma.

  9. Results confirmed the genetic association between GSDMB (show GSDMB Proteins)/ ORMDL3 and childhood asthma and show significant differences in the DNA methylation (show HELLS Proteins) levels of ORMDL3 promoter of asthmatic children.

  10. Studies indicate that genetic variation of the ORMDL3 rs7216389 polymorphism may be a major independent predisposing factor for asthma in ethnically diverse populations.

Mouse (Murine) ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. Downregulation of ORMDL3 expression in mast cells enhances AKT (show AKT1 Proteins) and NF-kappaB (show NFKB1 Proteins)-directed signaling pathways and chemotaxis and contributes to the development of mast cell-mediated local inflammation in vivo.

  2. overexpression of ORMDL3 regulates ceramide homeostasis in cells in a complex manner and suggest that local FTY720 administration might be a useful therapeutic intervention for the control of allergic asthma.

  3. the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism

  4. These studies provide evidence that ORMDL3 plays an important role in vivo in airway remodeling potentially through ATF6 (show ATF6 Proteins) target genes.

  5. ORMDL3 promotes eosinophil trafficking and activation via regulation of CD18 (show ITGB2 Proteins), CD49d, and CD48 (show CD48 Proteins).

  6. signaling pathway cAMP/PKA/CREB (show CREB1 Proteins) plays an important role in regulating ORMDL3 expression

ORMDL3 Protein Profile

Protein Summary

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).

Gene names and symbols associated with ORMDL3

  • ORM1-like 3 (S. cerevisiae) (ORMDL3)
  • ORM1-like 3 (S. cerevisiae) (Ormdl3)
  • 2810011N17Rik protein
  • AI315223 protein
  • LRRGT00183 protein

Protein level used designations for ORMDL3

ORM1-like protein 3 , liver regeneration-related protein LRRGT00183

GENE ID SPECIES
94103 Homo sapiens
66612 Mus musculus
360618 Rattus norvegicus
615368 Bos taurus
100479284 Ailuropoda melanoleuca
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