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Negative regulator of sphingolipid synthesis (By similarity). Additionally we are shipping ORMDL1 Antibodies (12) and and many more products for this protein.
ORMDL1 downregulation modestly increased levels of sphingosine, S1P (show MBTPS1 ELISA Kits), and ceramide in HepG2 cells.
ORMDL1, ORMDL2 (show ORMDL2 ELISA Kits) and ORMDL3 (show ORMDL3 ELISA Kits) mediate the feedback response in ceramide biosynthesis.
Adoplin-1/ORMDL-1 displays reduced expression in association with presenilin mutations; Adoplin-1 & two highly homologous genes (adoplin-2 (show ORMDL2 ELISA Kits), -3) are a gene family that encodes transmembrane proteins that may play roles in gamma-secretase complex maturation
free-cholesterol accumulation diminishes ORMDL1 expression
Negative regulator of sphingolipid synthesis (By similarity).
ORM1-like protein 1
, uncharacterized protein LOC100188936