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anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Antibodies

The product of OTUB1 is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. Additionally we are shipping OTU Domain, Ubiquitin Aldehyde Binding 1 Proteins (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OTUB1 107260 Q7TQI3
OTUB1 55611 Q96FW1
OTUB1 293705 B2RYG6
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Top anti-OTU Domain, Ubiquitin Aldehyde Binding 1 Antibodies at antibodies-online.com

Showing 10 out of 109 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-OTUB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... Host: Rabbit  Target Name: OTUB1  Sample Tissue: 293T  Antibody Diluti... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB OTUB1 monoclonal antibody (M09), clone 1C12. Western Blot analysis of ... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-OTUB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC210648 overexpress plasmid (Re... HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$482.90
Details
Mouse Goat Un-conjugated ELISA, WB ABIN302152 (0.05µg/ml) staining of Mouse Brain lysate (35µg protein in... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Sample (50 ug of whole cell lysate) A: Mouse liver 12% SDS PA... ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, WB OTUB1 monoclonal antibody (M09), clone 1C12. Western Blot analysis of ... Detection limit for recombinant GST tagged OTUB1 is 1 ng/ml as a captu... 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

OTUB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Rat (Rattus) , , , ,
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Top referenced anti-OTU Domain, Ubiquitin Aldehyde Binding 1 Antibodies

  1. Human Monoclonal OTUB1 Primary Antibody for WB - ABIN393473 : Edelmann, Kramer, Altun, Kessler: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion. in The FEBS journal 2010 (PubMed)
    Show all 5 references for ABIN393473

  2. Human Polyclonal OTUB1 Primary Antibody for WB - ABIN2787016 : Juris, Shah, Shokat, Dixon, Vacratsis: Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. in FEBS letters 2006 (PubMed)

More Antibodies against OTU Domain, Ubiquitin Aldehyde Binding 1 Interaction Partners

Pig (Porcine) OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) interaction partners

  1. OTUB1 localizes predominantly in the nucleus and is highly expressed in the brain, liver, spleen, lung, kidney, large intestine, small intestine, stomach, ovary, uterus and thym (show PTMA Antibodies)

Human OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) interaction partners

  1. the data suggest that OTUB1 limits the ubiquitination and degradation of FOXM1 (show FOXM1 Antibodies) in breast cancer and has a key role in genotoxic agent resistance.

  2. substrate for hydroxylation by FIH (show CASR Antibodies) on N22

  3. Data show that casein kinase 2 (CK2 (show CSNK2A1 Antibodies))-mediated phosphorylation of deubiquitylating enzyme OTUB1 at Ser16 causes nuclear accumulation of OTUB1.

  4. OTUB1 promoted the metastasis of CRC (show CALR Antibodies) cell lines.

  5. After viral infection, HSCARG (show NMRAL1 Antibodies) interacted with tumor necrosis receptor-associated factor 3 (TRAF3 (show TRAF3 Antibodies)) and inhibited its ubiquitination by promoting the recruitment of OTUB1 to TRAF3 (show TRAF3 Antibodies).

  6. These data reveal novel insights into the Otub1 inhibition of E2 wherein monoubiquitination promotes the interaction of Otub1 with UbcH5 (show UBE2D1 Antibodies) and the function to suppress it.

  7. OTUB1 enhances TGF-beta (show TGFB1 Antibodies) signaling by inhibiting the ubiquitylation and degradation of active SMAD2 (show SMAD2 Antibodies) and SMAD3 (show SMAD3 Antibodies).

  8. A second role of OTUB1-E2 interactions is to stimulate OTUB1 cleavage of Lys48 polyubiquitin. This stimulation is regulated by the ratio of charged to uncharged E2 and by the concentration of Lys48-linked polyubiquitin and free ubiquitin.

  9. These results suggest that OTUB1 regulates NF-kappaB (show NFKB1 Antibodies) and MAPK (show MAPK1 Antibodies) signalling pathways and TNF (show TNF Antibodies)-dependent cell death by modulating c-IAP1 (show BIRC2 Antibodies) stability.

  10. the crystal structure of human OTUB1 in complex with human UBC13 (show UBE2N Antibodies) and MMS2 (show UBE2V2 Antibodies)

OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Antigen Profile

Protein Summary

The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with OTUB1

  • OTU domain, ubiquitin aldehyde binding 1 (OTUB1) antibody
  • OTU domain, ubiquitin aldehyde binding 1b (otub1b) antibody
  • OTU domain, ubiquitin aldehyde binding 1 (otub1) antibody
  • OTU domain, ubiquitin aldehyde binding 1 (Otub1) antibody
  • similar to HSPC263 (RGD1565010) antibody
  • AI850305 antibody
  • fa19h07 antibody
  • MGC131231 antibody
  • OTB1 antibody
  • OTU1 antibody
  • otub1 antibody
  • wu:fa19h07 antibody
  • zgc:92839 antibody

Protein level used designations for OTUB1

ubiquitin thioesterase OTUB1 , OTU domain, ubiquitin aldehyde binding 1 , otubain 1 , Ubiquitin thioesterase OTUB1 , ubiquitin thioesterase otub1 , OTU domain-containing ubiquitin aldehyde-binding protein 1 , deubiquitinating enzyme OTUB1 , otubain-1 , ubiquitin-specific-processing protease OTUB1 , OTU-domain Ubal-binding 1 , ubiquitin-specific protease otubain 1

GENE ID SPECIES
100302092 Sus scrofa
436773 Danio rerio
476039 Canis lupus familiaris
717989 Macaca mulatta
734823 Xenopus laevis
742797 Pan troglodytes
100286700 Salmo salar
100529028 Ictalurus punctatus
107260 Mus musculus
55611 Homo sapiens
540984 Bos taurus
293705 Rattus norvegicus
611228 Canis lupus familiaris
314660 Rattus norvegicus
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