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OTU Domain, Ubiquitin Aldehyde Binding 2 Proteins (OTUB2)

OTUB2 encodes one of several deubiquitylating enzymes. Additionally we are shipping OTU Domain, Ubiquitin Aldehyde Binding 2 Antibodies (85) and OTU Domain, Ubiquitin Aldehyde Binding 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OTUB2 78990 Q96DC9
OTUB2 68149 Q9CQX0
Rat OTUB2 OTUB2 314405  
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Top OTU Domain, Ubiquitin Aldehyde Binding 2 Proteins at antibodies-online.com

Showing 7 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$140.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

OTUB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced OTU Domain, Ubiquitin Aldehyde Binding 2 Proteins

  1. Human OTUB2 Protein expressed in Escherichia coli (E. coli) - ABIN2005521 : Balakirev, Tcherniuk, Jaquinod, Chroboczek: Otubains: a new family of cysteine proteases in the ubiquitin pathway. in EMBO reports 2003 (PubMed)
    Show all 2 references for ABIN2005521

  2. Human OTUB2 Protein expressed in Escherichia coli (E. coli) - ABIN667440 : Edelmann, Iphöfer, Akutsu, Altun, di Gleria, Kramer, Fiebiger, Dhe-Paganon, Kessler: Structural basis and specificity of human otubain 1-mediated deubiquitination. in The Biochemical journal 2009 (PubMed)
    Show all 2 references for ABIN667440

More Proteins for OTU Domain, Ubiquitin Aldehyde Binding 2 (OTUB2) Interaction Partners

Human OTU Domain, Ubiquitin Aldehyde Binding 2 (OTUB2) interaction partners

  1. OTUB2 fine-tunes the speed of double-strand break-induced ubiquitination so that the appropriate DNA repair pathway is chosen

  2. OTUB2 is a novel promoter of via (show INS Proteins)bility and insulin secretion in human beta cells. OTUB2 acts through the inhibition of NF-kappaB signalling.

  3. Findings suggest that OTUB1 (show OTUB1 Proteins) and OTUB2 negatively regulate virus-triggered type I IFN induction and cellular antiviral response by deubiquitinating TRAF3 (show TRAF3 Proteins) and -6.

  4. Data report the first crystal structure of an OTU superfamily protein, otubain 2, at 2.1 A resolution and propose a model for otubain-ubiquitin binding.

Mouse (Murine) OTU Domain, Ubiquitin Aldehyde Binding 2 (OTUB2) interaction partners

  1. siRNAs of OTUB2 impaired insulin (show INS Proteins) secretion both under basal conditions and in cytokine-treated MIN6 cells

OTU Domain, Ubiquitin Aldehyde Binding 2 (OTUB2) Protein Profile

Protein Summary

This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function\; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde)\; an active cysteine protease site is present in the OTU domain.

Gene names and symbols associated with OTUB2

  • OTU domain, ubiquitin aldehyde binding 2 (OTUB2)
  • OTU domain, ubiquitin aldehyde binding 2 (otub2)
  • OTU domain, ubiquitin aldehyde binding 2 (Otub2)
  • 2010015L18Rik protein
  • 4930586I02Rik protein
  • AI413508 protein
  • AW557219 protein
  • C14orf137 protein
  • OTB2 protein
  • OTU2 protein
  • OTUB2 protein

Protein level used designations for OTUB2

OTU domain, ubiquitin aldehyde binding 2 , OTU domain-containing ubiquitin aldehyde-binding protein 2 , deubiquitinating enzyme OTUB2 , otubain-2 , ubiquitin thioesterase OTUB2 , ubiquitin-specific protease otubain 2 , ubiquitin-specific-processing protease OTUB2

GENE ID SPECIES
467539 Pan troglodytes
495334 Xenopus laevis
706795 Macaca mulatta
100124322 Xenopus (Silurana) tropicalis
78990 Homo sapiens
504880 Bos taurus
68149 Mus musculus
314405 Rattus norvegicus
480420 Canis lupus familiaris
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