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OTU Domain Containing 5 (OTUD5) ELISA Kits

OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. Additionally we are shipping OTUD5 Antibodies (50) and OTUD5 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human OTUD5 OTUD5 55593 Q96G74
Anti-Mouse OTUD5 OTUD5 54644 Q3U2S4
Anti-Rat OTUD5 OTUD5 363452 Q2YDU3
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More ELISA Kits for OTUD5 Interaction Partners

Human OTU Domain Containing 5 (OTUD5) interaction partners

  1. Findings have uncovered an apoptotic signaling cascade linking PDCD5 (show PDCD5 ELISA Kits), OTUD5, and p53 (show TP53 ELISA Kits) during genotoxic stress responses.

  2. OTUD5 is required for the stabilization and the activation of a p53 (show TP53 ELISA Kits) response

  3. Here the authors show that phosphorylation of the human deubiquitinase DUBA (OTUD5) at a single residue, Ser177, is both necessary and sufficient to activate the enzyme.

  4. data identify DUBA as a negative regulator of innate immune responses

Mouse (Murine) OTU Domain Containing 5 (OTUD5) interaction partners

  1. data identify DUBA as a cell-intrinsic suppressor of IL-17 (show IL17A ELISA Kits) production

OTUD5 Antigen Profile

Antigen Summary

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with OTUD5

  • OTU domain containing 5 (OTUD5) antibody
  • OTU domain containing 5a (otud5a) antibody
  • OTU domain containing 5 (Otud5) antibody
  • AA407879 antibody
  • AI553596 antibody
  • BB114028 antibody
  • DUBA antibody
  • DXImx46e antibody
  • otud5 antibody
  • Sfc7 antibody
  • si:bz30i22.1 antibody
  • si:rp71-30i22.1 antibody
  • zgc:154072 antibody

Protein level used designations for OTUD5

OTU domain containing 5 , OTU domain-containing protein 5 , OTU domain-containing protein 5-A , deubiquitinating enzyme A , deubiquinating enzyme A , DUBA

GENE ID SPECIES
480911 Canis lupus familiaris
539145 Bos taurus
555459 Danio rerio
737927 Pan troglodytes
55593 Homo sapiens
54644 Mus musculus
363452 Rattus norvegicus
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