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OCLN encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Additionally we are shipping Occludin Kits (42) and Occludin Proteins (9) and many more products for this protein.
Showing 10 out of 111 products:
Human Monoclonal Occludin Primary Antibody for IF, WB - ABIN395206
Raikwar, Vandewalle, Thomas: Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia. in American journal of physiology. Renal physiology 2010
Show all 5 references for ABIN395206
Human Polyclonal Occludin Primary Antibody for IF (p), IHC (p) - ABIN687337
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. in Neuroscience letters 2011
Show all 4 references for ABIN687337
Human Polyclonal Occludin Primary Antibody for EIA, IF - ABIN500409
Tsukita, Furuse, Itoh: Multifunctional strands in tight junctions. in Nature reviews. Molecular cell biology 2001
Show all 4 references for ABIN500409
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, WB - ABIN968360
Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. in The Journal of cell biology 1996
Show all 3 references for ABIN968360
Human Polyclonal Occludin Primary Antibody for WB - ABIN657822
Michta, Hopcraft, Narbus, Kratovac, Israelow, Sourisseau, Evans: Species-specific regions of occludin required by hepatitis C virus for cell entry. in Journal of virology 2010
Show all 2 references for ABIN657822
Dog (Canine) Polyclonal Occludin Primary Antibody for IHC (fro), IF - ABIN1108503
Van Itallie, Anderson: Occludin confers adhesiveness when expressed in fibroblasts. in Journal of cell science 1997
Human Monoclonal Occludin Primary Antibody for IF, IHC (p) - ABIN337048
Krueger, Härtig, Reichenbach, Bechmann, Michalski: Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions. in PLoS ONE 2013
Cow (Bovine) Polyclonal Occludin Primary Antibody for WB - ABIN2775619
Shen, Weber, Turner: The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. in The Journal of cell biology 2008
This is report of a family of Indian origin with two affected sibs and segregation of a homozygous novel OCLN mutation in the exon 3(NG_028291.1(OCLN_v001):c.252delC).
Data show that estrogen mediates control of hepatitis C virus through the G-protein-coupled estrogen receptor (show ESR1 Antibodies) 30 (GPR30 (show GPER Antibodies)) pathway leading to cleavage of occludin by Matrix Metalloproteinase-9 (MMP-9 (show MMP9 Antibodies)).
In hepatitis C virus -infected human livers, occludin and ADRP (show PLIN2 Antibodies) mRNA expression levels correlated with each other. Hepatitis C virus increases occludin expression via the upregulation of ADRP (show PLIN2 Antibodies).
Data show that claudin-6 (CLDN6 (show CLDN6 Antibodies)) R209Q and occludin (OCLN) P24A mutations do not affect HCV pseudoparticles (HCVpp) entry.
resistance to HCV in HIV+ patients may be related to genetic variation in SCARB1 (show SCARB1 Antibodies) or OCLN
Angiopoietin-1 (show ANGPT1 Antibodies) Regulates Brain Endothelial Permeability through PTPN-2 (show PTPN2 Antibodies) Mediated Tyrosine Dephosphorylation of Occludin
TIMP1 (show TIMP1 Antibodies) downregulates MMP-2 (show MMP2 Antibodies) activity and inhibits the degradation of occluding in Caco-2 intestinal cells
Study uncovers a novel antiviral effect of miR (show MLXIP Antibodies)-122 on human liver cells and shows that over-expression of miR (show MLXIP Antibodies)-122 can decrease HCV entry into hepatocytes through down-regulation of OCLN.
Lipid raft-associated processes, such as PP2A (show PPP2R4 Antibodies) and MMP-2 (show MMP2 Antibodies) activation, participate in PCB153-induced disruption of occludin function in brain endothelial barrier.
miR (show MLXIP Antibodies)-18a and RUNX1 (show RUNX1 Antibodies) could reversely regulate the permeability of blood-tumor barrier as well as the expressions and distributions of ZO-1 (show TJP1 Antibodies), occludin and claudin-5 (show CLDN5 Antibodies).
ADMA has potent adverse effects on cell proliferation, intracellular ROS (show ROS1 Antibodies) generation, cell permeability, levels of ICAM-1 (show ICAM1 Antibodies), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (show TJP1 Antibodies) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (show VEGFA Antibodies)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
Tricellulin (show MARVELD2 Antibodies) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
PHD3 (show EGLN3 Antibodies) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (show EGLN3 Antibodies) in stabilizing occludin
Zonula occludens-1 (show TJP1 Antibodies), occludin and E-cadherin (show CDH1 Antibodies) expression and organization in salivary glands
Our study demonstrates spatiotemporal alterations in occludin mRNA- and protein-expression, indicating that Cx43 (show GJA1 Antibodies) might act as a regulator for blood-testis-barrier
Occludin and Claudin-1 (show CLDN1 Antibodies) expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
Hypoxic induction of CAV1 (show CAV1 Antibodies) in the colon was essential for intestinal barrier integrity by regulating occludin expression.
Activation of RhoA (show RHOA Antibodies)/ROCK1 (show ROCK1 Antibodies) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin/ZO-1 (show TJP1 Antibodies), which can be corrected by simvastatin.
Similar levels of occludin gene expression were detected.
ZO-1 (show TJP1 Antibodies) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight junction protein occludin TM4 minus
, thiopurine methyltransferase
, tight junction protein occludin
, tight-junction protein
, occludin b