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Occludin Proteins (OCLN)

OCLN encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Additionally we are shipping Occludin Antibodies (105) and Occludin Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OCLN 4950  
OCLN 18260 Q61146
Rat OCLN OCLN 83497 Q6P6T5
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Top Occludin Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

OCLN Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Occludin (OCLN) Interaction Partners

Human Occludin (OCLN) interaction partners

  1. This is report of a family of Indian origin with two affected sibs and segregation of a homozygous novel OCLN mutation in the exon 3(NG_028291.1(OCLN_v001):c.252delC).

  2. Data show that estrogen mediates control of hepatitis C virus through the G-protein-coupled estrogen receptor (show ESR1 Proteins) 30 (GPR30) pathway leading to cleavage of occludin by Matrix Metalloproteinase-9 (MMP-9 (show MMP9 Proteins)).

  3. In hepatitis C virus -infected human livers, occludin and ADRP (show PLIN2 Proteins) mRNA expression levels correlated with each other. Hepatitis C virus increases occludin expression via the upregulation of ADRP (show PLIN2 Proteins).

  4. Data show that claudin-6 (CLDN6 (show CLDN6 Proteins)) R209Q and occludin (OCLN) P24A mutations do not affect HCV pseudoparticles (HCVpp) entry.

  5. resistance to HCV in HIV+ patients may be related to genetic variation in SCARB1 (show SCARB1 Proteins) or OCLN

  6. Angiopoietin-1 (show ANGPT1 Proteins) Regulates Brain Endothelial Permeability through PTPN-2 (show PTPN2 Proteins) Mediated Tyrosine Dephosphorylation of Occludin

  7. TIMP1 (show TIMP1 Proteins) downregulates MMP-2 (show MMP2 Proteins) activity and inhibits the degradation of occluding in Caco-2 intestinal cells

  8. Study uncovers a novel antiviral effect of miR (show MLXIP Proteins)-122 on human liver cells and shows that over-expression of miR (show MLXIP Proteins)-122 can decrease HCV entry into hepatocytes through down-regulation of OCLN.

  9. Lipid raft-associated processes, such as PP2A (show PPP2R4 Proteins) and MMP-2 (show MMP2 Proteins) activation, participate in PCB153-induced disruption of occludin function in brain endothelial barrier.

  10. miR (show MLXIP Proteins)-18a and RUNX1 (show RUNX1 Proteins) could reversely regulate the permeability of blood-tumor barrier as well as the expressions and distributions of ZO-1 (show TJP1 Proteins), occludin and claudin-5 (show CLDN5 Proteins).

Cow (Bovine) Occludin (OCLN) interaction partners

  1. ADMA has potent adverse effects on cell proliferation, intracellular ROS (show ROS1 Proteins) generation, cell permeability, levels of ICAM-1 (show ICAM1 Proteins), and the tight-junction protein occludin

  2. the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades

  3. cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (show TJP1 Proteins) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity

  4. These data demonstrate a novel mechanism of VEGF (show VEGFA Proteins)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.

Mouse (Murine) Occludin (OCLN) interaction partners

  1. Tricellulin (show MARVELD2 Proteins) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.

  2. These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.

  3. occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.

  4. PHD3 (show EGLN3 Proteins) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (show EGLN3 Proteins) in stabilizing occludin

  5. Zonula occludens-1 (show TJP1 Proteins), occludin and E-cadherin (show CDH1 Proteins) expression and organization in salivary glands

  6. Our study demonstrates spatiotemporal alterations in occludin mRNA- and protein-expression, indicating that Cx43 (show GJA1 Proteins) might act as a regulator for blood-testis-barrier

  7. Occludin and Claudin-1 (show CLDN1 Proteins) expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.

  8. Hypoxic induction of CAV1 (show CAV1 Proteins) in the colon was essential for intestinal barrier integrity by regulating occludin expression.

  9. Activation of RhoA (show RHOA Proteins)/ROCK1 (show ROCK1 Proteins) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin/ZO-1 (show TJP1 Proteins), which can be corrected by simvastatin.

  10. Similar levels of occludin gene expression were detected.

Pig (Porcine) Occludin (OCLN) interaction partners

  1. ZO-1 (show TJP1 Proteins) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.

Rabbit Occludin (OCLN) interaction partners

Occludin (OCLN) Protein Profile

Protein Summary

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Gene names and symbols associated with Occludin Proteins (OCLN)

  • occludin (OCLN)
  • occludin (ocln)
  • occludin (Ocln)
  • occludin (ocln-b)
  • occludin a (oclna)
  • AI503564 protein
  • BLCPMG protein
  • Ocl protein
  • ocln protein
  • oclnb protein
  • tpmt protein
  • wu:fd23h10 protein
  • wu:fi13c01 protein
  • zgc:56359 protein
  • zgc:113992 protein

Protein level used designations for Occludin Proteins (OCLN)

occludin , tight junction protein occludin TM4 minus , thiopurine methyltransferase , occludin-like , tight junction protein occludin , tight-junction protein , occludin b

GENE ID SPECIES
100073306 Equus caballus
4950 Homo sapiens
548702 Xenopus (Silurana) tropicalis
700504 Macaca mulatta
741925 Pan troglodytes
100031291 Monodelphis domestica
100077299 Ornithorhynchus anatinus
100386012 Callithrix jacchus
100462976 Oncorhynchus mykiss
100583496 Nomascus leucogenys
100506658 Homo sapiens
403844 Canis lupus familiaris
512405 Bos taurus
18260 Mus musculus
83497 Rattus norvegicus
398133 Xenopus laevis
397236 Sus scrofa
100527952 Cavia porcellus
100338492 Oryctolagus cuniculus
396026 Gallus gallus
443201 Ovis aries
100174190 Pongo abelii
405757 Danio rerio
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