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Transcription factor that plays a role in the regulation of embryonic heart and urogenital development (By similarity).. Additionally we are shipping OSR1 Antibodies (78) and OSR1 Proteins (8) and many more products for this protein.
Osr1/Osr2 normally repress bmp4 (show BMP4 ELISA Kits) expression in the lateral plate mesoderm prior to respiratory specification.
nephrogenic transcription factors (osr1, osr2, hnf1b (show HNF1B ELISA Kits), lhx1 (show LHX1 ELISA Kits), pax8 (show PAX8 ELISA Kits))play important role in nephrogenesis but have no pronephros induction potential upon overexpression; they activate transcription cascades reflecting activation by activin A (show INHBA ELISA Kits), retinoic acid
In summary, our study implicated a gene network involving Tbx5 (show TBX5 ELISA Kits), Osr1 (show OXSR1 ELISA Kits) and Pcsk6 (show PCSK6 ELISA Kits) interaction in second heart field for atrial septation, providing a molecular framework for understanding the role of Tbx5 (show TBX5 ELISA Kits) in congenital heart disease ontogeny.
SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are both stimulators of Kir2.1 (show KCNJ2 ELISA Kits) activity.
SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are powerful stimulators of the intestinal Na+-coupled phosphate co-transporter NaPi-IIb (show SLC34A2 ELISA Kits)
OSR1 (show OXSR1 ELISA Kits) protein has both the potential to up-regulate KCNQ1 (show KCNQ1 ELISA Kits)/E1 protein abundance in the cell membrane, an effect possibly participating in the regulation of cell volume, excitability, epithelial transport and metabolism.
SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are powerful negative regulators of the excitatory glutamate (show GRIN1 ELISA Kits) transporters EAAT1 (show SLC1A3 ELISA Kits) and EAAT2 (show SLC1A2 ELISA Kits).
SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are negative regulators of EAAT3 (show SLC1A1 ELISA Kits) activity
OSR1 (show OXSR1 ELISA Kits) has the capacity to downregulate the peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2 (show SLC15A2 ELISA Kits) by decreasing the carrier protein abundance in the cell membrane
Both, SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits), are negative regulators of the creatine transporter SLC6A8 (show SLC6A8 ELISA Kits)
SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2 (show CLCN2 ELISA Kits)
The findings of the present study showed, for the first time, the role of the OSR1 (show OXSR1 ELISA Kits) rs12329305 polymorphism in the development of congenital malformations in cases of stillborn/neonatal death.
Tbx5 (show TBX5 ELISA Kits) and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation.
odd-skipped related 1 is involved in regulation of mammalian kidney development
ROMK1 (show KCNJ1 ELISA Kits) protein abundance and activity are down-regulated by SPAK (show STK39 ELISA Kits) and OSR1
study identifies a separation of functions for the WNK1 (show WNK1 ELISA Kits)-activated protein kinases OSR1 and SPAK (show STK39 ELISA Kits) in mediating proliferation, invasion, and gene expression in endothelial cells
WNK 1 (show WNK1 ELISA Kits), 3, 4, OSR1, and SPAK (show STK39 ELISA Kits) signaling system known to play a role in regulating the phosphorylation status, and hence activity of the CCCs in other tissues, is also present in the rat and human lenses.
Osr1 plays crucial roles in Six2 (show SIX2 ELISA Kits)-dependent maintenance of nephron progenitors during mammalian nephrogenesis.
Data indicate that Activin A (show INHBA ELISA Kits) and retinoic acid (RA) induced theto embryonic stem cells (mESCs) expression of marker genes and proteins for intermediate mesoderm, odd-skipped related 1 (Osr1) and Wilms Tumor 1 (Wt1 (show WT1 ELISA Kits)).
Odd-skipped related-1 controls neural crest chondrogenesis during tongue development.
OSR1 is expressed in proximal renal tubules and participates in the regulation of FGF23 (show FGF23 ELISA Kits) release and renal tubular phosphate transport.
WNK1 (show WNK1 ELISA Kits) activation of the OSR1 signaling cascade is an essential pathway that regulates angiogenesis and cardiac formation during mouse embryo development.
findings identify osr1 as a Nodal-induced, negative feedback regulator of Nodal signaling that acts at the earliest stages of endoderm differentiation to limit the number of endoderm progenitors.
Our results place osr1 in a framework of transcriptional regulators that control the expression of podocin and nephrin (show NPHS1 ELISA Kits) and thereby mediate podocyte differentiation.
The Osr1 and Osr2 genes act in the pronephric anlage downstream of retinoic acid signaling and upstream of Wnt2b (show WNT2B ELISA Kits) to maintain pectoral fin development.
osr1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate.
Transcription factor that plays a role in the regulation of embryonic heart and urogenital development (By similarity).
odd-skipped related 1 (Drosophila)
, protein odd-skipped-related 1
, zinc finger transcription factor
, odd-skipped homolog
, oxidative-stress responsive 1