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Olfactomedin 4 Proteins (OLFM4)

OLFM4 was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. Additionally we are shipping Olfactomedin 4 Antibodies (66) and Olfactomedin 4 Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OLFM4 10562 Q6UX06
OLFM4 380924  
OLFM4 290409  
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Top Olfactomedin 4 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human Olfactomedin-4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 2 to 3 Days
$385.00
Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$777.70
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Mammalian Cells Human His tag   10 μg Log in to see 5 Days
$242.55
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_HEK-293 Human His tag   0.05 mg Log in to see 2 to 3 Days
$687.50
Details

OLFM4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Olfactomedin 4 Proteins

  1. Human OLFM4 Protein expressed in Human Cells - ABIN2004463 : Zhang, Liu, Tang, Chen, Wang, Pack, Zhuang, Rodgers: Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development. in Gene 2002 (PubMed)
    Show all 4 references for ABIN2004463

  2. Human OLFM4 Protein expressed in HEK-293 Cells - ABIN2181562 : Liu, Lee, Liu, Wang, Rodgers: Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis. in Blood 2010 (PubMed)
    Show all 3 references for ABIN2181562

More Proteins for Olfactomedin 4 (OLFM4) Interaction Partners

Human Olfactomedin 4 (OLFM4) interaction partners

  1. OLFM4 is proved to as a functional target for miR (show MLXIP Proteins)-590.

  2. Olfactomedin 4 is a novel tumor marker for triple-negative breast cancer for predicting and prognosis.

  3. OLFM4 is downregulated by miR (show MLXIP Proteins)-486-5p, which contributes to ovarian cancer tumorigenesis. Conversely, estrogen receptor (show ESR1 Proteins) signaling downregulates miR (show MLXIP Proteins)-486-5p and upregulates OLFM4 expression, slowing the development and progression of ovarian cancer.

  4. Data show that olfactomedin 4 (OLFM4) is highly expressed in proliferating benign epithelial cells and in some carcinoma cells.

  5. olfactomedin 4 appears to play a critical role in regulating progression of prostate cancer, and has potential as a new biomarker for prostate cancer.

  6. Study demonstrates that epigenetic silencing of OLFM4 enhances gastric cancer cell invasion via activation of FAK (show PTK2 Proteins) signaling.

  7. suppression of OLFM4 expression may be a promising strategy in the development of novel cancer therapeutic drugs

  8. Patients with an OLFM4 gene expression level above -7.5 were 6 times more likely to develop severe disease, after correction for age at hospitalization and gestational age.

  9. Using a human vaginal epithelial cell line, the expression of mucin (show SLC13A2 Proteins) 5 subtype B and olfactomedin-4 were down-regulated in response to N9, suggesting these markers could apply to humans

  10. findings suggest that OLFM4 is not only involved in early stages of gastric carcinogenesis but also a useful prognostic marker for advanced gastric cancer

Mouse (Murine) Olfactomedin 4 (OLFM4) interaction partners

  1. olfactomedin 4 appears to play a critical role in regulating progression of prostate cancer, and has potential as a new biomarker for prostate cancer.

  2. OLFM4 may function as a tumor suppressor and an anti-metastatic gene during tumor progression

  3. Olfm4 deletion can successfully enhance immune defense against S. aureus, but not A. fumigatus, in chronic granulomatous disease mice.

  4. OLFM4 exerts considerable influence on the host defense against H. pylori infection acting through NOD1 (show NOD1 Proteins) and NOD2 mediated NF-kappaB (show NFKB1 Proteins) activation and subsequent cytokines and chemokines production, which in turn inhibit host immune response.

Olfactomedin 4 (OLFM4) Protein Profile

Protein Summary

This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion.

Gene names and symbols associated with Olfactomedin 4 Proteins (OLFM4)

  • olfactomedin 4 (olfm4)
  • olfactomedin 4 (OLFM4)
  • olfactomedin 4 (LOC100225360)
  • olfactomedin 4 (Olfm4)
  • olfactomedin 4 (LOC100354781)
  • olfactomedin-4-like (LOC100737320)
  • bA209J19.1 protein
  • GC1 protein
  • Gm296 protein
  • Gm913 protein
  • GW112 protein
  • hGC-1 protein
  • hOLfD protein
  • olfactomedin-4 protein
  • OlfD protein
  • OLM4 protein
  • pPD4 protein
  • tiarin protein
  • UNQ362 protein

Protein level used designations for Olfactomedin 4 Proteins (OLFM4)

olfactomedin 4 , G-CSF-stimulated clone 1 protein , antiapoptotic protein GW112 , olfactomedin-4 , OLM4 , PU.1 difference product 4

GENE ID SPECIES
398296 Xenopus laevis
467367 Pan troglodytes
549797 Xenopus (Silurana) tropicalis
694574 Macaca mulatta
100225360 Taeniopygia guttata
100586206 Nomascus leucogenys
10562 Homo sapiens
485470 Canis lupus familiaris
515082 Bos taurus
380924 Mus musculus
290409 Rattus norvegicus
100354781 Oryctolagus cuniculus
100729206 Cavia porcellus
418826 Gallus gallus
101121867 Ovis aries
100737320 Sus scrofa
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