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Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. Additionally we are shipping OMP Antibodies (58) and many more products for this protein.
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This study demonstrated that the OMP plays a key regulatory role in Olfactory Receptor Neurons physiology by controlling multiple facets of the odorant response.
Three olfactory receptors (olfr544, olfr558, and olfr1386) were expressed in the olfactory marker protein (+) cells of the bladder and thyroid.
the actions of OMP in olfactory transduction carry through to the primary sensory representations of olfactory stimuli in adult mice in vivo.
Olfactory sensory neurons undergo an olfactory marker protein-dependent functional maturation process that coincides with early development of the smell function, which is essential for pups to form preference for their mother.
crystal structure of the olfactory marker protein at 2.3 A resolution
We report the identification of an olfactory marker protein binding partner, Bex2 (show BEX2 Proteins), by phage-display screening of an olfactory mucosal cDNA-library
alterations in mucosal activity may serve as the substrate for the behaviorally observed changes in odorant quality perception in olfactory marker protein null mutant
OMP concentration is up- or down-regulated depending on the amount of odor stimulation olfactory receptor neurons receive.
Axons overshoot their target layer and grow into the external plexiform layer in OMP null mice. However, in the absence of OMP, overshooting axons are more persistent and remain prominent until 5 weeks postnatally, after which their numbers decrease.
These observations explain the deficits in odour detection threshold and odour quality discrimination seen in the OMP(-/-) mice
Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade.
olfactory marker protein
, olfactory neuronal-specific protein