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anti-One Cut Homeobox 1 (ONECUT1) Antibodies

transcription factor; acts as a transcriptional activator of liver promoter sequence. Additionally we are shipping One Cut Homeobox 1 Kits (18) and One Cut Homeobox 1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ONECUT1 15379 O08755
ONECUT1 3175 Q9UBC0
ONECUT1 25231 P70512
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Top anti-One Cut Homeobox 1 Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-ONECUT1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-ONECUT1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB ONECUT1 Antibody (C-term) (ABIN656637) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the ONECUT1 antibody detected the ONECUT1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ONECUT1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). This demonstrates the ONECUT1 antibody detected the ONECUT1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB Sample Type: Frozen section of mouse embryo at et12.5Primary Dilution: 1:500Secondary Dilution: 1:2000Antigen Retrevial method: Citrate buffer (pH=6) Image Submitted By: Fré,dé,ric ClotmanUniversité, catholique de Louvain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-HNF6 mouse monoclonal antibody (ABIN2452681) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HNF6 (RC218219). Immunofluorescent staining of HeLa cells using anti-HNF6 mouse monoclonal antibody (ABIN2452681). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with ONECUT1 antibody ABIN462211 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ONECUT1 antibody ABIN462211 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-HNF6 antibody, IHC(P) IHC(P): Rat Liver Tissue Anti-HNF6 antibody, IHC(F) IHC(F): Rat Liver Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

ONECUT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,
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Rat (Rattus)


Top referenced anti-One Cut Homeobox 1 Antibodies

  1. Human Polyclonal ONECUT1 Primary Antibody for EIA, WB - ABIN953903 : Lee, Kim, Kim, Park, Shong, Seong, Ha, Choi: Orphan nuclear receptor SHP interacts with and represses hepatocyte nuclear factor-6 (HNF-6) transactivation. in The Biochemical journal 2008 (PubMed)
    Show all 4 references for ABIN953903

  2. Dog (Canine) Polyclonal ONECUT1 Primary Antibody for IHC, WB - ABIN2780599 : Huang, Mei, Yu, Zhang, Han, Jiang, Zhou: Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig. in Acta histochemica 2009 (PubMed)
    Show all 3 references for ABIN2780599

  3. Dog (Canine) Polyclonal ONECUT1 Primary Antibody for WB - ABIN2780598 : Jiang, Zhang, Kayed, Zheng, Giese, Friess, Kleeff: Loss of ONECUT1 expression in human pancreatic cancer cells. in Oncology reports 2007 (PubMed)
    Show all 2 references for ABIN2780598

  4. Human Polyclonal ONECUT1 Primary Antibody for WB - ABIN656637 : Rausa, Hughes, Costa: Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against One Cut Homeobox 1 Interaction Partners

Mouse (Murine) One Cut Homeobox 1 (ONECUT1) interaction partners

  1. HNF6 binding was sex independent at a majority of binding sites, and HNF6 peaks were frequently associated with cobinding by multiple other liver transcription factors, consistent with HNF6 playing a global regulatory role in both male and female liver.

  2. with Lmx1a (show LMX1A Antibodies) to promote ventral midbrain neural stem cells differentiation into dopamine neuron through Wnt1 (show WNT1 Antibodies)-Lmx1a (show LMX1A Antibodies) pathway.

  3. Onecut1 and Onecut2 (show ONECUT2 Antibodies) have roles in operating downstream of Pax6 (show PAX6 Antibodies) to regulate horizontal cell development

  4. similar to Onecut1, Onecut2 (show ONECUT2 Antibodies) is also necessary for the formation of normal numbers of horizontal cells in the developing retina.

  5. identified downstream genes of Oc1 and Oc2 that shows that the onecut factors suppress the production of the late cell type, rods, indicating that the two factors contribute to the competence of retinal progenitor cells for early retinal cell fates

  6. Sex-dependent growth hormone (show GH1 Antibodies) secretion patterns affect the expression of HNF6 in liver.

  7. Liver cell plasticity is competent for regeneration of intrahepatic bile duct independent of Notch (show NOTCH1 Antibodies) signaling via Rbpj (show RBPJ Antibodies) and Hnf6.

  8. in Hnf6-/- mice, the organization of Purkinje cells became abnormal during a second phase of their development.

  9. Insight on the role of HNF6 in pancreatic cancer development could lead to its use as a biomarker for early detection and prognosis.

  10. Findings suggest that Onecut1 suppresses MafA (show MAFA Antibodies) gene expression through the Foxa2 (show FOXA2 Antibodies)-binding site.

Zebrafish One Cut Homeobox 1 (ONECUT1) interaction partners

  1. findings identify vps33b (show VPS33B Antibodies) is a novel downstream target gene of the hnf6/vhnf1 (show HNF1B Antibodies) pathway that regulates bile duct development in zebrafish

Human One Cut Homeobox 1 (ONECUT1) interaction partners

  1. Reduced HNF6 expression is associated with metastasis of cholangiocarcinoma.

  2. HNF6 is a novel host factor that can restrict hepatitis B virus replication via both transcriptional and posttranscriptional mechanisms.

  3. The negative correlation between HNF6 expression and pancreatic cancer progression suggests that HNF6 maintains pancreatic epithelial homeostasis, and that its loss contributes to the progression from intraepithelial neoplasms to ductal adenocarcinoma.

  4. HNF6 plays an important role in the gene regulation of CYP3A4 (show CYP3A4 Antibodies) during development from the fetal period to the postnatal period.

  5. HNF6 inhibits EMT (show ITK Antibodies), cell migration, and invasive growth through a mechanism involving the transcriptional activation of p53 (show TP53 Antibodies).

  6. Mutations at the -5/-6 site of the F9 promotor account for the majority of hemophilia B Leyden cases and disrupt the binding of ONECUT1 and ONECUT2 (show ONECUT2 Antibodies).

  7. HNF6 and Sox9 (show SOX9 Antibodies) are new biomarkers of pancreatic acinar-to-ductal metaplasia and constitute candidate targets for preventive treatment in cases when acinar-to-ductal metaplasia may lead to cancer.

  8. Hepatocyte nuclear factor 6 is one of the liver-enriched transcription factors, it utilizes the bipartite onecut-homeodomain sequence to localize to the nuclear compartment and bind specific DNA sequences of numerous target gene promoters

  9. functional knockdown of FOXA2 (show FOXA2 Antibodies) recovered HNF6 activity and inhibited growth of tumor-cells and may possibly represent a novel therapeutic target in primary and secondary liver malignancies

  10. HNF6 has a role as a coactivator protein to potentiate the transcriptional activity of another liver factor, FoxA2 (show FOXA2 Antibodies)

One Cut Homeobox 1 (ONECUT1) Antigen Profile

Protein Summary

This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ONECUT1

  • one cut domain, family member 1 (Onecut1) antibody
  • one cut domain, family member 1 (onecut1) antibody
  • one cut homeobox 1 (ONECUT1) antibody
  • one cut homeobox 1 (Onecut1) antibody
  • D9Ertd423e antibody
  • Hfh12 antibody
  • HNF-6 antibody
  • HNF-6a antibody
  • HNF6 antibody
  • HNF6A antibody
  • Hnf6b antibody
  • OC-1 antibody
  • oc1 antibody
  • onecut1l antibody
  • zgc:65904 antibody
  • zgc:77450 antibody

Protein level used designations for ONECUT1

HNF-3/forkhead homolog 12 , hepatic nuclear factor 6 , hepatocyte nuclear factor 6 , one cut homeobox 1 , hnf-6 , hnf6 , one cut domain, family member 1, like , hepatocyte nuclear factor 6, alpha , one cut domain family member 1 , one cut domain, family member 1 , HNF-6 , hepatocyte nuclear factor 6 alpha

GENE ID SPECIES
15379 Mus musculus
393545 Danio rerio
3175 Homo sapiens
487558 Canis lupus familiaris
25231 Rattus norvegicus
503584 Bos taurus
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