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a class of opioid receptors; show selective affinity for the endogenous opioid dynorphin. Additionally we are shipping Opioid Receptor, kappa 1 Proteins (3) and Opioid Receptor, kappa 1 Kits (2) and many more products for this protein.
Showing 10 out of 118 products:
Human Polyclonal OPRK1 Primary Antibody for WB - ABIN1881595
Bruijnzeel: kappa-Opioid receptor signaling and brain reward function. in Brain research reviews 2009
Show all 2 references for ABIN1881595
Human Polyclonal OPRK1 Primary Antibody for ELISA, ICC - ABIN4329272
Li, Chen, Liu-Chen: N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway. in Biochemistry 2007
Show all 2 references for ABIN4329272
Human Polyclonal OPRK1 Primary Antibody for WB - ABIN317765
Niwa, Rowbotham, Lambert: Evaluation of primary opioid receptor antibodies for use in western blotting. in British journal of anaesthesia 2012
Cow (Bovine) Polyclonal OPRK1 Primary Antibody for WB - ABIN2792280
Edenberg, Wang, Tian, Pochareddy, Xuei, Wetherill, Goate, Hinrichs, Kuperman, Nurnberger, Schuckit, Tischfield, Foroud: A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence. in Human molecular genetics 2008
ZFOR3 is a unique model to study kappa opioid receptor functionality
These findings provide evidence that previously demonstrated KOR-mediated reduction in intraocular pressure could be caused, in part, by NO production in both the ciliary body and the trabecular meshwork.
genetic association studies in a population in Denmark: Data suggest that carriers/heterozygotes of the C allele (CC/CT) of OPRK SNP rs6473799 report a 30.4% higher mechanical visceral pain tolerance threshold than non-carriers.
Molecular switches of the kappa opioid receptor triggered by 6'-GNTI (show MGAT1 Antibodies) and 5'-GNTI (show MGAT1 Antibodies) have been described.
The study successfully developed a population PKPD model for oxycodone across three experimental pain types and investigated the association between 18 SNPs across all three opioid receptor genes (OPRM1 (show OPRM1 Antibodies), OPRK1, OPRD1 (show OPRD1 Antibodies)) and analgesic response from oxycodone. None of the selected polymorphisms were significantly associated with analgesic response of oxycodone.
findings suggest that SNPs in opioid receptors and the PNOC (show PNOC Antibodies) genes are associated with NAS (show SCN9A Antibodies) severity.
OPRK1 promoter hypermethylation might increase the risk of AD through its regulation on the gene expression of OPRK1.
OX1R (show HCRTR1 Antibodies) and KOR heterodimerize, and this heterodimer associates with Galphas (show GNAS Antibodies), leading to increased protein kinase A (PKA) signaling pathway activity, including upregulation of intracellular cAMP levels.
The structure of the dynorphin (1-13) peptide (dynorphin) bound to the human kappa opioid receptor (KOR) has been determined by liquid-state NMR spectroscopy.
RGS2 and RGS4 are new interacting partners that play key roles in G protein coupling to negatively regulate kappa-OmicronR signaling.
Data show that the crystallographic structures of the mouse mu-opioid receptor (show OPRM1 Antibodies) (MOPr (show OPRM1 Antibodies)) and human kappa-opioid receptor (KOPr) indicate putative interfacial interactions.
Here we describe three experimental procedures we used to evaluate the interaction between hKOPR and 14-3-3zeta (show YWHAZ Antibodies): co-immunoprecipitation, pull-down assay and immunofluorescence microscopy.
Study showed that Dyn (show PDYN Antibodies)-A, the endogenous kappa opioid receptor agonist, significantly hyperpolarized and inhibited neurons in the paraventricular nucleus of mouse thalamus
Suggest that mixed cardiac ion channel blockade my mediated the antiarrhythmia actions of kappa-opioid receptor antagonist PD117,302.
Anti-nociception mediated by a KOR agonist is blocked by a DOR agonist
Findings suggest that activation of kappa opioid receptor (kappa-opioid receptor) reduces hyperglycemia in streptozotocin-induced diabetic mice.
findings show that, during prolonged heroin abstinence, delta opioid receptors regulate hedonic homeostasis, while mu opioid receptor (show OPRM1 Antibodies) signaling in serotonergic pathways and kappa opioid receptors together control social behaviors
kappa-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice.
The data of this study provide evidence that KORs on VTA DA neurons are necessary to mediate KOR-mediated aversive behavior.
Natural food reward and systemic ghrelin (show GHRL Antibodies) activate Kappa opioid receptors in the ventral tegmental area.
Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R (show TACR3 Antibodies) and KOR) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).
Data (including data from KOR knockout mice) suggest that KOR modulates GABAergic synaptic responses in the central amygdala and modulates the effects of ethanol as one of multiple opioid system-dependent actions of ethanol in the central amygdala.
a class of opioid receptors\; show selective affinity for the endogenous opioid dynorphin
, kappa-type opioid receptor
, opioid receptor, kappa 1
, kappa opioid receptor
, Opiate receptor, kappa-1
, opioid receptor, kappa 2