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Opioid Receptor, kappa 1 Proteins (OPRK1)

a class of opioid receptors\; show selective affinity for the endogenous opioid dynorphin [RGD, Feb 2006].. Additionally we are shipping Opioid Receptor, kappa 1 Antibodies (103) and Opioid Receptor, kappa 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OPRK1 4986 P41145
OPRK1 18387 P33534
Rat OPRK1 OPRK1 29335 P34975
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Top Opioid Receptor, kappa 1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

OPRK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Opioid Receptor, kappa 1 (OPRK1) Interaction Partners

Zebrafish Opioid Receptor, kappa 1 (OPRK1) interaction partners

  1. ZFOR3 is a unique model to study kappa opioid receptor functionality

Rabbit Opioid Receptor, kappa 1 (OPRK1) interaction partners

  1. These findings provide evidence that previously demonstrated KOR-mediated reduction in intraocular pressure could be caused, in part, by NO production in both the ciliary body and the trabecular meshwork.

Human Opioid Receptor, kappa 1 (OPRK1) interaction partners

  1. findings suggest that SNPs in opioid receptors and the PNOC genes are associated with NAS (show SCN9A Proteins) severity.

  2. OPRK1 promoter hypermethylation might increase the risk of AD through its regulation on the gene expression of OPRK1.

  3. OX1R (show HCRTR1 Proteins) and KOR heterodimerize, and this heterodimer associates with Galphas (show GNAS Proteins), leading to increased protein kinase A (PKA) signaling pathway activity, including upregulation of intracellular cAMP levels.

  4. The structure of the dynorphin (1-13) peptide (dynorphin) bound to the human kappa opioid receptor (KOR) has been determined by liquid-state NMR spectroscopy.

  5. RGS2 and RGS4 are new interacting partners that play key roles in G protein coupling to negatively regulate kappa-OmicronR signaling.

  6. Data show that the crystallographic structures of the mouse mu-opioid receptor (show OPRM1 Proteins) (MOPr (show OPRM1 Proteins)) and human kappa-opioid receptor (KOPr) indicate putative interfacial interactions.

  7. Here we describe three experimental procedures we used to evaluate the interaction between hKOPR and 14-3-3zeta (show YWHAZ Proteins): co-immunoprecipitation, pull-down assay and immunofluorescence microscopy.

  8. Studied differential DNA-protein interactions of PDYN (show PDYN Proteins) and OPRK1 SNPs significantly associated with alcohol dependence.

  9. Low OPRK1 expression is associated with liver metastases of small bowel neuroendocrine tumors.

  10. Data indicate that replacement of the 3-hydroxyl substituent of the 4-(3-hydroxyphenyl) group of JDTic with a H, F, or Cl substituent leads to potent and selective kappa opioid receptor (KOR) antagonists.

Mouse (Murine) Opioid Receptor, kappa 1 (OPRK1) interaction partners

  1. Study showed that Dyn (show PDYN Proteins)-A, the endogenous kappa opioid receptor agonist, significantly hyperpolarized and inhibited neurons in the paraventricular nucleus of mouse thalamus

  2. Suggest that mixed cardiac ion channel blockade my mediated the antiarrhythmia actions of kappa-opioid receptor antagonist PD117,302.

  3. Anti-nociception mediated by a KOR agonist is blocked by a DOR agonist

  4. Findings suggest that activation of kappa opioid receptor (kappa-opioid receptor) reduces hyperglycemia in streptozotocin-induced diabetic mice.

  5. findings show that, during prolonged heroin abstinence, delta opioid receptors regulate hedonic homeostasis, while mu opioid receptor (show OPRM1 Proteins) signaling in serotonergic pathways and kappa opioid receptors together control social behaviors

  6. kappa-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice.

  7. The data of this study provide evidence that KORs on VTA DA neurons are necessary to mediate KOR-mediated aversive behavior.

  8. Natural food reward and systemic ghrelin (show GHRL Proteins) activate Kappa opioid receptors in the ventral tegmental area.

  9. Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R (show TACR3 Proteins) and KOR) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).

  10. Data (including data from KOR knockout mice) suggest that KOR modulates GABAergic synaptic responses in the central amygdala and modulates the effects of ethanol as one of multiple opioid system-dependent actions of ethanol in the central amygdala.

Opioid Receptor, kappa 1 (OPRK1) Protein Profile

Protein Summary

a class of opioid receptors\; show selective affinity for the endogenous opioid dynorphin

Gene names and symbols associated with OPRK1

  • opioid receptor, kappa 1 (oprk1)
  • opioid receptor, kappa 1 (OPRK1)
  • kappa opioid receptor (LOC780448)
  • opioid receptor, kappa 1 (LOC100354170)
  • opioid receptor, kappa 1 (Oprk1)
  • K-OR-1 protein
  • KOR protein
  • KOR-1 protein
  • LOC780448 protein
  • MSL-1 protein
  • OPRK protein
  • OPRK1 protein
  • Oprk2 protein
  • R21 protein

Protein level used designations for OPRK1

ZFOR3 , ZfKOR , kappa-type opioid receptor , opioid receptor, kappa 1 , kappa opioid receptor , K-OR-1 , KOR-1 , Opiate receptor, kappa-1 , opioid receptor, kappa 2

GENE ID SPECIES
360139 Danio rerio
428533 Gallus gallus
486951 Canis lupus familiaris
780448 Ovis aries
100152118 Sus scrofa
100354170 Oryctolagus cuniculus
100587333 Nomascus leucogenys
4986 Homo sapiens
540519 Bos taurus
18387 Mus musculus
29335 Rattus norvegicus
100135587 Cavia porcellus
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