Opsin 1 (Cone Pigments), Long-Wave-Sensitive (OPN1LW) ELISA Kits

OPN1LW encodes for a light absorbing visual pigment of the opsin gene family. Additionally we are shipping and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human OPN1LW OPN1LW 5956 P04000
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More ELISA Kits for OPN1LW Interaction Partners

Human Opsin 1 (Cone Pigments), Long-Wave-Sensitive (OPN1LW) interaction partners

  1. LVAVA haplotype of the OPN1LW gene and MVAVA haplotype of the OPN1MW (show OPN1MW ELISA Kits) gene cause apparently nonsyndromic high myopia in young patients but lead to progressive cone-rod dystrophy with deuteranopia and protanopia in middle-aged patients corresponding to a previously unknown disease course.

  2. Findings show that OPN1LW mutations underlie the cone dysfunction in all of the subjects tested, the color vision defect can be caused either by the same mutation or a gene rearrangement at the same locus

  3. Data suggest that insights into dimerization interface of red cone opsin should aid investigations of the structure and function of GPCR cell signaling.

  4. Our study confirms the findings that unique variants in OPN1LW are responsible for both syndromic and nonsyndromic X-linked high myopia mapped to MYP1.

  5. Using several human ROP (show STXBP1 ELISA Kits) enhancer/promoter-luciferase reporter constructs, the study found that thyroid hormone receptor beta 2 (show THRB ELISA Kits) increased luciferase activities through the 5'-UTR (show UTS2R ELISA Kits) and intron 3-4 region.

  6. Identification of one single red-green OPN1LW/MW hybrid gene harboring a point mutation that associates with blue cone monochromatism.

  7. The photoreceptor phenotype associated with OPN1LW and OPN1MW (show OPN1MW ELISA Kits) mutations is highly variable. These findings have implications for the potential restoration of visual function in subjects with opsin (show RHO ELISA Kits) mutations.

  8. Missense mutation in both OPN1LW and OPN1MW (show OPN1MW ELISA Kits) cause X-linked cone dystrophy.

  9. Opsin (show RHO ELISA Kits) expression in terminally differentiated mammalian cones remains subject to control by thyroid hormone (show PTH ELISA Kits) through its receptor TRbeta2.

  10. Mutations in the LW/MW cone opsin (show RHO ELISA Kits) gene array can, therefore, lead to a spectrum of disease, ranging from color blindness to progressive cone dystrophy (XLCOD5).

Cow (Bovine) Opsin 1 (Cone Pigments), Long-Wave-Sensitive (OPN1LW) interaction partners

  1. an extended network of hydrogen bonds connects the agonist retinal binding site to the G protein binding site via conserved amino acid residues. dynamics of the hydrogen-bonding network inside opsin couples to interactions at the G protein binding site

  2. instability of the retinitis pigmentosa P23H mutant opsin (show RHO ELISA Kits)

  3. Ligand binding in opsin (show RHO ELISA Kits) apparently follows an induced-fit three-point interaction model, with the ring, 9-methyl group, and aldehyde group as the determining selection elements.

  4. the crystal structure of ligand-free native opsin (show RHO ELISA Kits) from bovine retinal rod cells at 2.9 angstrom (A) resolution

  5. 3.2 A crystal structure of the bovine Ops (show LRP5 ELISA Kits)*-GalphaCT peptide complex

  6. Mammalian rod opsin (show RHO ELISA Kits) biogenesis does not appear to have an absolute requirement for Cnx (show CANX ELISA Kits).

OPN1LW Antigen Profile

Antigen Summary

This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness.

Gene names and symbols associated with OPN1LW

  • opsin 1 (cone pigments), long-wave-sensitive (OPN1LW) antibody
  • opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan) (OPN1LW) antibody
  • CBBM antibody
  • CBP antibody
  • COD5 antibody
  • OPN1MW antibody
  • OPN1MW2 antibody
  • OPSN antibody
  • RCP antibody
  • ROP antibody

Protein level used designations for OPN1LW

cone dystrophy 5 (X-linked) , long-wave-sensitive opsin 1 , red cone photoreceptor pigment , red-sensitive opsin , opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan) , red opsin , opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) , opsin 1 (cone pigments), medium-wave-sensitive 2 , green opsin , iodopsin , red-sensitive pigment

5956 Homo sapiens
282293 Bos taurus
493959 Felis catus
403778 Canis lupus familiaris
100033892 Equus caballus
396421 Gallus gallus
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