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May play some role in mitochondrial processes (By similarity). Additionally we are shipping OPA3 Antibodies (3) and many more products for this protein.
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Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome.
Mutant Opa3 protein retains its mitochondrial localization and induces disrupted mitochondrial morphology. Opa3 accumulates in the lens. The results may reflect a slow turnover of Opa3 protein in vivo and may be important in normal lens physiology.
to investigate the OPA3 function we have generated a novel ENU-induced mutant mouse carrying a missense mutation in the OPA3 gene. In the heterozygous state, the mice appear uncompromised. In the homozygous state mice display some of the features of MGA.
mitochondrial OPA3 is required to limit HMG-CoA-derived MGC and protect the electron transport chain against inhibitory compounds in a zebrafish model of Costeff Syndrome
The present study is the first report of the OPA3 mutation in dilated cardiomyopathy affected cows outside Switzerland.
the nonsense mutation c.343C>T in the bovine OPA3 gene causes the late-onset dilated cardiomyopathy in Red Holstein cattle.
May play some role in mitochondrial processes (By similarity).
optic atrophy 3 protein homolog
, optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
, mitochondrial optic atrophy 3 protein