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anti-Origin Recognition Complex, Subunit 6 (ORC6) Antibodies

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Additionally we are shipping ORC6 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ORC6 291927  
ORC6 23594 Q9Y5N6
ORC6 56452  
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Top anti-ORC6 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ORC6L Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rat Un-conjugated ChIP, IP, WB 50 μL Log in to see 5 to 6 Days
$429.10
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded TOV-21G ... WB Image Sample(30 ug whole cell lysate) A:MOLT4 , 12% SDS PAGE antibo... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated DB, ICC Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% p... 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IF, IP, WB Immunoprecipitation of ORC6L transfected lysate using anti-ORC6L MaxPa... Western Blot analysis of ORC6L expression in transfected 293T cell lin... 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated DB, ICC   50 μg Log in to see 8 to 10 Days
$493.17
Details

ORC6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus) , ,

Human , , , ,
, , ,
Mouse (Murine) , ,

Top referenced anti-ORC6 Antibodies

  1. Cow (Bovine) Polyclonal ORC6 Primary Antibody for WB - ABIN2786008 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  2. Human Monoclonal ORC6 Primary Antibody for ChIP, IP - ABIN108574 : Ritzi, Tillack, Gerhardt, Ott, Humme, Kremmer, Hammerschmidt, Schepers: Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. in Journal of cell science 2003 (PubMed)

  3. Human Polyclonal ORC6 Primary Antibody for WB - ABIN452310 : Dhar, Dutta: Identification and characterization of the human ORC6 homolog. in The Journal of biological chemistry 2000 (PubMed)

More Antibodies against ORC6 Interaction Partners

Fruit Fly (Drosophila melanogaster) Origin Recognition Complex, Subunit 6 (ORC6) interaction partners

  1. Drosophila Orc6 protein, the smallest subunit of the origin recognition complex (ORC), directly binds to septin complex and facilitates septin filament formation.

  2. Drosophila ORC6 protein cytokinetic function resides in a domain distinct from its replication activity

  3. These studies provide a molecular analysis for the functional requirement of Orc6 in replicative functions of ORC in Drosophila and suggest that Orc6 may contribute to the sequence preferences of ORC in targeting to the origins.

  4. These results show that the interaction of Orc6 with the septin (show SEPT1 Antibodies) complex is dependent on the coiled-coil domain of Pnut, and suggest an active role for Orc6 in septin (show SEPT1 Antibodies) complex function.

  5. In a cross-species complementation experiment, the expression of human Orc6 in Drosophila Orc6 mutant cells rescued DNA replication, suggesting that this function of the protein is conserved among metazoans.

Human Origin Recognition Complex, Subunit 6 (ORC6) interaction partners

  1. The present report expands the clinical phenotype associated with ORC6 mutations to include severely abnormal embryological development suggesting a possible genotype-phenotype correlation.

  2. our results suggest that Meier-Gorlin syndrome mutations in Orc6 impair the formation of ORC hexamers, interfering with appropriate ORC functions

  3. findings show that Orc6 not only interacts with Orc1 (show ORC1L Antibodies)-Orc5 (show ORC5 Antibodies) but also with the initiation factor Cdc6 (show CDC6 Antibodies), and that Orc6 functions at different stages of the replication initiation process.

  4. Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB (show GTF2B Antibodies).

  5. results implicate Orc6 as an essential gene that coordinates chromosome replication and segregation with cytokinesis

  6. Study using HCT116 haplo-insufficient (show TGFb Antibodies) cells and Orc2 hypomorphic cells demonstrates that the binding of human Ku to replication origins precedes that of Orc-3 (show ORC3 Antibodies), -4, and -6 subunit binding.

  7. Orc6 has a role in sensitizing human colon cancer cells to 5-fluorouracil and cisplatin

  8. In a cross-species complementation experiment, the expression of human Orc6 in Drosophila Orc6 mutant cells rescued DNA replication, suggesting that this function of the protein is conserved among metazoans.

Mouse (Murine) Origin Recognition Complex, Subunit 6 (ORC6) interaction partners

  1. Study reports that ORC6L is another component required for acquisition of DNA replication competence that is absent in mouse oocytes.

ORC6 Antigen Profile

Protein Summary

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Gene names and symbols associated with ORC6

  • origin recognition complex, subunit 6 (Orc6) antibody
  • Origin recognition complex subunit 6 (Orc6) antibody
  • origin recognition complex, subunit 6 (ORC6) antibody
  • origin recognition complex subunit 6 (ORC6) antibody
  • origin recognition complex subunit 6 (CpipJ_CPIJ005016) antibody
  • origin recognition complex subunit 6 (SJAG_01267) antibody
  • origin recognition complex subunit 6 (orcF) antibody
  • origin recognition complex subunit 6 (LOC100284755) antibody
  • origin recognition complex, subunit 6 (orc6) antibody
  • 6720420I10Rik antibody
  • ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 antibody
  • ATORC6 antibody
  • CG1584 antibody
  • DDBDRAFT_0186183 antibody
  • DDBDRAFT_0233113 antibody
  • DDB_0186183 antibody
  • DDB_0233113 antibody
  • Dmel\\CG1584 antibody
  • DmORC6 antibody
  • DmORC 6 antibody
  • LOC100284755 antibody
  • ORC antibody
  • orc6 antibody
  • orc6l antibody
  • origin recognition complex protein 6 antibody
  • ORIGIN RECOGNITION COMPLEX SUBUNIT 6 antibody
  • rDmORC antibody
  • T2P11.3 antibody
  • T2P11_3 antibody

Protein level used designations for ORC6

origin recognition complex subunit 6 , origin recognition complex, subunit 6-like , CG1584-PA , Orc6-PA , origin recognition complex, subunit 6 like

GENE ID SPECIES
291927 Rattus norvegicus
36017 Drosophila melanogaster
415749 Gallus gallus
465140 Pan troglodytes
839227 Arabidopsis thaliana
6036630 Culex quinquefasciatus
7048414 Schizosaccharomyces japonicus yFS275
8624765 Dictyostelium discoideum AX4
100284755 Zea mays
549939 Xenopus (Silurana) tropicalis
23594 Homo sapiens
482492 Canis lupus familiaris
515476 Bos taurus
56452 Mus musculus
Selected quality suppliers for anti-ORC6 (ORC6) Antibodies
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