You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Ornithine Carbamoyltransferase (OTC) Antibodies

This nuclear gene encodes a mitochondrial matrix enzyme. Additionally we are shipping Ornithine Carbamoyltransferase Kits (33) and Ornithine Carbamoyltransferase Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OTC 5009 P00480
OTC 25611 P00481
OTC 18416 P11725
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Ornithine Carbamoyltransferase Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of OTC Antibody (Center) (ABIN390915) in HepG2 cell line lysates (35 µg/lane). OTC (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatoarcinoma with OTC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of OTC Antibody (Center) in HepG2 cell line lysates (35ug/lane). OTC (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-OTC Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 12% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using OTC, antibody at 1:250 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat intestine tissue labeled with Anti OTC Polyclonal Antibody, Unconjugated (ABIN720505) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB OTC antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of intestinal villus (arrows) in Human Intestine. Magnification is at 400X OTC antibody used at 2.5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details

OTC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,
,
, , , , ,
Rat (Rattus)


Mouse (Murine) ,


,

Top referenced anti-Ornithine Carbamoyltransferase Antibodies

  1. Cow (Bovine) Polyclonal OTC Primary Antibody for IHC, WB - ABIN2773791 : Tanaka, Wada, Maruyama, Tanaka, Takikawa, Komatsu: Hyperammonemia-induced encephalopathy due to ornithine transcarbamylase deficiency in an adult woman: identification of novel missense mutations. in Journal of gastroenterology 2005 (PubMed)
    Show all 3 references for ABIN2773791

  2. Human Polyclonal OTC Primary Antibody for FACS, IHC (p) - ABIN390915 : Hansmannel, Lendon, Pasquier, Dumont, Hannequin, Chapuis, Laumet, Ayral, Galimberti, Scarpini, Campion, Amouyel, Lambert: Is the ornithine transcarbamylase gene a genetic determinant of Alzheimer's disease? in Neuroscience letters 2008 (PubMed)

More Antibodies against Ornithine Carbamoyltransferase Interaction Partners

Human Ornithine Carbamoyltransferase (OTC) interaction partners

  1. In Korean patients with OTC deficiency, mutations in OTC are genetically heterogeneous.

  2. Sanger sequencing of the ornithine transcarbamylase (OTC) gene revealed a novel hemizygous deletion at the fourth nucleotide of intron 4 (c.386+4delT) in a child with hyperammonemia and his asymptomatic mother.

  3. Ornithine transcarbamylase deficiency was genetically heterogeneous in seven Korean patients with confirmed ornithine transcarbamylase deficiency diagnosis by biochemical findings and/or genetic analysis, together with two novel mutations in the OTC gene

  4. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences

  5. OTC mutation and phenotype in ornithine transcarbamylase deficiency

  6. aim of this study was to provide clues for recognition of OTCD in adults and analyze the environmental factors that, interacting with OTC gene mutations, might have triggered acute clinical manifestations

  7. HNF-4alpha (show HNF4A Antibodies) most likely plays an essential role in the initiation of OTC transcription in human.

  8. Data indicate that all of the three patients have carried ornithine transcarbamylase gene mutations, patients 1 and 2 were both hemizygous for mutation c.586G> A(p.D196N).

  9. V339G and W332S mutations of OTC have been discovered for the first time

  10. carriers of the ornithine transcarbamylase (OTC) mutation are at risk for developing hyperammonemia coma during the postpartum period and at times of metabolic stress.

Mouse (Murine) Ornithine Carbamoyltransferase (OTC) interaction partners

  1. Gene correction in adult OTC-deficient mice was lower and accompanied by larger deletions that ablated residual expression from the endogenous OTC gene, leading to diminished protein tolerance and lethal hyperammonemia on a chow diet

  2. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences

  3. Serum OCT (show Plxna2 Antibodies) seemed to reflect tumor necrosis factor-alpha (show TNF Antibodies)-mediated hepatic damage in diabetic obese mice and could be useful in the application for non-alcoholic fatty liver disease with features of metabolic syndrome, such as obesity and diabetes.

  4. in vivo regulation by HNF4alpha (show HNF4A Antibodies)

  5. Results highlight the importance of the interaction between the OTC spf-ash mutation (ornithine transcarbamylase deficiency) and genetic backgrounds on metabolic phenotypes (ureagenesis, arginine metabolism, and nitric oxide production).

  6. Phenotypic correction of OTC deficiency using low-dose helper-dependent adenoviral vectors is reported.

  7. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Ornithine Carbamoyltransferase (OTC) Antigen Profile

Protein Summary

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Gene names and symbols associated with OTC

  • ornithine carbamoyltransferase (OTC) antibody
  • ornithine carbamoyltransferase (argF) antibody
  • ornithine carbamoyltransferase (argF-2) antibody
  • ornithine carbamoyltransferase (atpD-2) antibody
  • ornithine carbamoyltransferase (CNC04300) antibody
  • ornithine carbamoyltransferase (Otc) antibody
  • ornithine transcarbamylase (Otc) antibody
  • AI265390 antibody
  • BA4351 antibody
  • F1B16.13 antibody
  • F1B16_13 antibody
  • OCTD antibody
  • ornithine carbamoyltransferase antibody
  • PSPTO4164 antibody
  • Sf antibody
  • spf antibody

Protein level used designations for OTC

ornithine carbamoyltransferase , OTCase , ornithine carbamoyltransferase, mitochondrial , ornithine transcarbamylase , sparse fur

GENE ID SPECIES
100050268 Equus caballus
1087574 Bacillus anthracis str. Ames
1168159 Shewanella oneidensis MR-1
1185844 Pseudomonas syringae pv. tomato str. DC3000
1790857 Rhodopirellula baltica SH 1
2687999 Geobacter sulfurreducens PCA
2797905 Listeria monocytogenes serotype 4b str. F2365
3105054 Methylococcus capsulatus str. Bath
3195160 Ruegeria pomeroyi DSS-3
3229331 Dehalococcoides ethenogenes 195
3231583 Campylobacter jejuni RM1221
3256472 Cryptococcus neoformans var. neoformans JEC21
3728051 Carboxydothermus hydrogenoformans Z-2901
3927820 Ehrlichia chaffeensis str. Arkansas
5009 Homo sapiens
480878 Canis lupus familiaris
397438 Sus scrofa
280887 Bos taurus
25611 Rattus norvegicus
395735 Gallus gallus
101102207 Ovis aries
843869 Arabidopsis thaliana
18416 Mus musculus
Selected quality suppliers for anti-Ornithine Carbamoyltransferase (OTC) Antibodies
Did you look for something else?