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Ornithine Carbamoyltransferase (OTC) ELISA Kits

This nuclear gene encodes a mitochondrial matrix enzyme. Additionally we are shipping Ornithine Carbamoyltransferase Antibodies (94) and Ornithine Carbamoyltransferase Proteins (18) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
OTC 5009 P00480
OTC 25611 P00481
OTC 18416 P11725
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Top Ornithine Carbamoyltransferase ELISA Kits at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.312 1.25 96 Tests Log in to see 11 to 13 Days
$910.56
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Mouse 0.78 3.12 96 Tests Log in to see 11 to 13 Days
$910.56
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Rat 10-250 ng/mL 96 Tests Log in to see 11 to 13 Days
$785.71
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Rabbit
96 Tests Log in to see 8 to 9 Days
$770.00
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Guinea Pig
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$770.00
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Monkey
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$770.00
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Pig
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$770.00
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Chicken
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$770.00
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Dog
96 Tests Log in to see 11 to 13 Days
$801.43
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Goat
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$801.43
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More ELISA Kits for Ornithine Carbamoyltransferase Interaction Partners

Human Ornithine Carbamoyltransferase (OTC) interaction partners

  1. In Korean patients with OTC deficiency, mutations in OTC are genetically heterogeneous.

  2. Sanger sequencing of the ornithine transcarbamylase (OTC) gene revealed a novel hemizygous deletion at the fourth nucleotide of intron 4 (c.386+4delT) in a child with hyperammonemia and his asymptomatic mother.

  3. Ornithine transcarbamylase deficiency was genetically heterogeneous in seven Korean patients with confirmed ornithine transcarbamylase deficiency diagnosis by biochemical findings and/or genetic analysis, together with two novel mutations in the OTC gene

  4. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences

  5. OTC mutation and phenotype in ornithine transcarbamylase deficiency

  6. aim of this study was to provide clues for recognition of OTCD in adults and analyze the environmental factors that, interacting with OTC gene mutations, might have triggered acute clinical manifestations

  7. HNF-4alpha (show HNF4A ELISA Kits) most likely plays an essential role in the initiation of OTC transcription in human.

  8. Data indicate that all of the three patients have carried ornithine transcarbamylase gene mutations, patients 1 and 2 were both hemizygous for mutation c.586G> A(p.D196N).

  9. V339G and W332S mutations of OTC have been discovered for the first time

  10. carriers of the ornithine transcarbamylase (OTC) mutation are at risk for developing hyperammonemia coma during the postpartum period and at times of metabolic stress.

Mouse (Murine) Ornithine Carbamoyltransferase (OTC) interaction partners

  1. Gene correction in adult OTC-deficient mice was lower and accompanied by larger deletions that ablated residual expression from the endogenous OTC gene, leading to diminished protein tolerance and lethal hyperammonemia on a chow diet

  2. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences

  3. Serum OCT (show Plxna2 ELISA Kits) seemed to reflect tumor necrosis factor-alpha (show TNF ELISA Kits)-mediated hepatic damage in diabetic obese mice and could be useful in the application for non-alcoholic fatty liver disease with features of metabolic syndrome, such as obesity and diabetes.

  4. in vivo regulation by HNF4alpha (show HNF4A ELISA Kits)

  5. Results highlight the importance of the interaction between the OTC spf-ash mutation (ornithine transcarbamylase deficiency) and genetic backgrounds on metabolic phenotypes (ureagenesis, arginine metabolism, and nitric oxide production).

  6. Phenotypic correction of OTC deficiency using low-dose helper-dependent adenoviral vectors is reported.

  7. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Ornithine Carbamoyltransferase (OTC) Antigen Profile

Antigen Summary

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Gene names and symbols associated with OTC

  • ornithine carbamoyltransferase (OTC) antibody
  • ornithine carbamoyltransferase (argF) antibody
  • ornithine carbamoyltransferase (argF-2) antibody
  • ornithine carbamoyltransferase (atpD-2) antibody
  • ornithine carbamoyltransferase (CNC04300) antibody
  • ornithine carbamoyltransferase (Otc) antibody
  • ornithine transcarbamylase (Otc) antibody
  • AI265390 antibody
  • BA4351 antibody
  • F1B16.13 antibody
  • F1B16_13 antibody
  • OCTD antibody
  • ornithine carbamoyltransferase antibody
  • PSPTO4164 antibody
  • Sf antibody
  • spf antibody

Protein level used designations for OTC

ornithine carbamoyltransferase , OTCase , ornithine carbamoyltransferase, mitochondrial , ornithine transcarbamylase , sparse fur

GENE ID SPECIES
100050268 Equus caballus
1087574 Bacillus anthracis str. Ames
1168159 Shewanella oneidensis MR-1
1185844 Pseudomonas syringae pv. tomato str. DC3000
1790857 Rhodopirellula baltica SH 1
2687999 Geobacter sulfurreducens PCA
2797905 Listeria monocytogenes serotype 4b str. F2365
3105054 Methylococcus capsulatus str. Bath
3195160 Ruegeria pomeroyi DSS-3
3229331 Dehalococcoides ethenogenes 195
3231583 Campylobacter jejuni RM1221
3256472 Cryptococcus neoformans var. neoformans JEC21
3728051 Carboxydothermus hydrogenoformans Z-2901
3927820 Ehrlichia chaffeensis str. Arkansas
5009 Homo sapiens
480878 Canis lupus familiaris
397438 Sus scrofa
280887 Bos taurus
25611 Rattus norvegicus
395735 Gallus gallus
101102207 Ovis aries
843869 Arabidopsis thaliana
18416 Mus musculus
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