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anti-Osteoclast Associated Receptor (OSCAR) Antibodies

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. Additionally we are shipping Osteoclast Associated Receptor Kits (33) and Osteoclast Associated Receptor Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OSCAR 232790 Q8VBT3
OSCAR 126014 Q8IYS5
Anti-Rat OSCAR OSCAR 292537  
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Top anti-Osteoclast Associated Receptor Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB OSCAR Antibody (C-term) western blot analysis in 293 cell line lysates... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 200 μg Log in to see 9 to 11 Days
$407.00
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (34.54 KDa) . 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

OSCAR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)

Human , , , ,
, ,

Top referenced anti-Osteoclast Associated Receptor Antibodies

  1. Human Polyclonal OSCAR Primary Antibody for ELISA, WB - ABIN185592 : Kim, Kim, Lee, Jin, Lee, Fisher, Kook, Kim, Choi, Kim: Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against Osteoclast Associated Receptor Interaction Partners

Mouse (Murine) Osteoclast Associated Receptor (OSCAR) interaction partners

  1. Data suggest that OSCAR is a collagen receptor (show ITGA2 Antibodies) that binds to specific collagen motifs and costimulates osteoclastogenesis in DAP12 (show TYROBP Antibodies)-deficient humans and mice.

  2. PU.1 and MITF (show MITF Antibodies) transcription factors synergistically activate OSCAR gene expression, which is further enhanced by the TRANCE-induced MKK6 (show MAP2K6 Antibodies)/p38 (show CRK Antibodies) signaling cascade.

  3. the FcRgamma (show FCER1G Antibodies)-mediated signal transduction by OSCAR is involved in osteoclast differentiation

  4. OSCAR but not TREM-2 (show TREM2 Antibodies) is involved in the positive feedback loop of the immunoreceptor-NFATc1 (show NFATC1 Antibodies) pathway during osteoclastogenesis

  5. analysis of a positive feedback circuit of TRANCE-induced activation of NFATc1 (show NFATC1 Antibodies), involving NFATc1 (show NFATC1 Antibodies)-mediated OSCAR expression and its subsequent activation of NFATc1 (show NFATC1 Antibodies), necessary for efficient differentiation of osteoclasts

  6. The overexpression of PIAS3 (show PIAS3 Antibodies) attenuates osteoclast formation and down-regulates the expression of NFATc1 (show NFATC1 Antibodies) and osteoclast-associated receptor (OSCAR), which are important modulators in osteoclastogenesis.

  7. Results indicate that USFs 1 and 2 serve as modulators in the induction of OSCAR and RANKL (show TNFSF11 Antibodies)-mediated osteoclastogenesis.

Human Osteoclast Associated Receptor (OSCAR) interaction partners

  1. Each domain of OSCAR binds a collagen triple-helical peptide; the primary site is on the C-terminal domain in contrast to GPVI (show GP6 Antibodies) and LAIR-1 (show LAIR1 Antibodies).

  2. OSCAR is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes.

  3. Data indicate that osteoclast associated receptor (OSCAR) was strongly expressed by the vasculature of active rheumatoid arthritis (RA) patients.

  4. endothelial cell-derived OSCAR was found to be involved in the STAT (show STAT1 Antibodies) signaling pathway and to affect monocyte adhesion.

  5. OSCAR is expressed in vascular endothelial cells and is regulated by oxLDL involving NFATc1 (show NFATC1 Antibodies)

  6. Data suggest that OSCAR is a collagen receptor (show ITGA2 Antibodies) that binds to specific collagen motifs and costimulates osteoclastogenesis in DAP12 (show TYROBP Antibodies)-deficient humans and mice.

  7. hOSCAR thus represents a novel class of molecule expressed by dendritic cells involved in the initiation of the immune response.

  8. ligation of OSCAR promotes dendritic cell survival by an ERK (show EPHB2 Antibodies)- and PI3K (show PIK3CA Antibodies)-dependent pathway, linked to expression of the Bcl-2 (show BCL2 Antibodies) and Bcl-x(L (show BCL2L1 Antibodies)) antiapoptotic molecules

  9. Human OSCAR mediates the rescue from apoptosis and the cooperation between dendritic cells and antigen-specific T cells that is prevented by CD85j (show LILRB1 Antibodies) receptor.

  10. analysis of a positive feedback circuit of TRANCE-induced activation of NFATc1 (show NFATC1 Antibodies), involving NFATc1 (show NFATC1 Antibodies)-mediated OSCAR expression and its subsequent activation of NFATc1 (show NFATC1 Antibodies), necessary for efficient differentiation of osteoclasts

Osteoclast Associated Receptor (OSCAR) Antigen Profile

Protein Summary

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with OSCAR

  • osteoclast associated, immunoglobulin-like receptor (OSCAR) antibody
  • osteoclast associated receptor (Oscar) antibody
  • osteoclast associated, immunoglobulin-like receptor (Oscar) antibody
  • osteoclast-associated receptor-like (LOC100351627) antibody
  • mOSCAR antibody
  • mOSCAR-M1 antibody
  • mOSCAR-M2 antibody
  • mOSCAR-M3 antibody
  • OSCAR antibody
  • PIgR-3 antibody
  • PIGR3 antibody
  • RGD1559897 antibody

Protein level used designations for OSCAR

osteoclast associated, immunoglobulin-like receptor , osteoclast associated, immunoglobulin-like receptor, isoform 4 , ocl178 , osteoclast-associated immunoglobulin-like receptor , osteoclast-associated receptor OSCAR , osteoclast associated receptor OSCAR-S1 , osteoclast associated receptor OSCAR-S2 , poly-Ig receptor 3 , polymeric immunoglobulin receptor 3 , osteoclast associated receptor

GENE ID SPECIES
484313 Canis lupus familiaris
748876 Pan troglodytes
100137562 Papio anubis
232790 Mus musculus
126014 Homo sapiens
292537 Rattus norvegicus
100351627 Oryctolagus cuniculus
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